US eligibility and preventable cardiovascular disease events from semaglutide in type 2 diabetes. [PDF]
Diab Vasc Dis ResKarthikeyan H, Fan W, Wong ND.
europepmc +1 more source
Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract
Advanced Robotics Research, EarlyView.We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis +7 more
wiley +1 more source
The Biological Effect of Platelet-Rich Plasma on Subacromial Bursa and Torn Supraspinatus Tendon: A Randomized Controlled Trial. [PDF]
Int J Mol SciPitsilos C +5 more
europepmc +1 more source
Advanced Robotics Research, EarlyView.Pak Biawak, a necrobot, embodies an unusual fusion of biology and robotics. Designed to repurpose natural structures after death, it challenges conventional boundaries between nature and engineering. Its movements are precise yet unsettling, raising questions about sustainability, ethics, and the untapped potential of biointegrated machines.
Leo Foulds +2 more
wiley +1 more source
The probiotic yeast <i>Saccharomyces boulardii</i> CNCM I-745 prevents autophagy in macrophages and epithelial cells infected with <i>Vibrio parahaemolyticus</i>. [PDF]
Front MicrobiolPontier-Bres R, Czerucka D.
europepmc +1 more source
A Soft Robotic Fish With a Dielectric Elastomer Actuator Body and Negative Stiffness Spine
Advanced Robotics Research, EarlyView.This work introduces a bio‐mimetic soft robotic fish driven by fiber‐reinforced dielectric elastomer actuators integrated as its body. By prestretching this active skin against a flexible spine, a negative stiffness system is created, enabling large‐amplitude bending.
Markus Koenigsdorff +4 more
wiley +1 more source
Identification and characterization of five anti-mitotic sesquiterpene lactones from <i>Arnica cordifolia</i>. [PDF]
Pharm BiolLockwood TC +4 more
europepmc +1 more source
Advanced Science, EarlyView.Nuclear metabolism oscillates during cell cycle progression. Quantitative chromatome proteomics and imaging reveal phase‐specific dynamics of PIP5K1A and nuclear PIP2, linking phosphatidylinositol metabolism to histone methylation. This work identifies nuclear lipid metabolism as a previously unrecognized regulatory axis coordinating chromatin ...
Antoni Gañez‐Zapater +13 more
wiley +1 more source
Does the Directive to Avoid Low Back Flexion Hinder Physical Performance? Examining Isometric Strength in Postures Adopted During Light Mass Lifting. [PDF]
Hum FactorsPinto BL, Beach TAC, Callaghan JP.
europepmc +1 more source
Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization
Advanced Science, EarlyView.This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin +11 more
wiley +1 more source