Temporal Interference Stimulation Enhances Neural Regeneration
Temporal interference (TI) stimulation is proposed as a non‐invasive approach to enhance neural regeneration in the deep brain. Theta‐band TI modulation selectively promotes neural progenitor cell differentiation in vitro and augments hippocampal neurogenesis in amouse model of Alzheimer's disease‐like amyloidosis.
Sofia Peressotti +15 more
wiley +1 more source
Irrational dynamics, superpitchfork bifurcation, and equilibrium hierarchy in a mass-spring system exhibiting chaos and bursting. [PDF]
Abobda LT.
europepmc +1 more source
We investigate whether Montessori and traditional schooling systems shape the developmental trajectory of large‐scale brain dynamics in different ways. We quantify the arrow of time (“non‐reversibility”) in neural activity during resting state and movie‐watching, revealing distinct maturational patterns.
Elvira del Agua +6 more
wiley +1 more source
US eligibility and preventable cardiovascular disease events from semaglutide in type 2 diabetes. [PDF]
Karthikeyan H, Fan W, Wong ND.
europepmc +1 more source
Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li +13 more
wiley +1 more source
The probiotic yeast <i>Saccharomyces boulardii</i> CNCM I-745 prevents autophagy in macrophages and epithelial cells infected with <i>Vibrio parahaemolyticus</i>. [PDF]
Pontier-Bres R, Czerucka D.
europepmc +1 more source
Advanced Dental Composite Technology via Bisilanized Dual‐Action Nanofillers for Biofilm Control
A multimodal research strategy has led to the development of an innovative resin‐based composite (RBC) with dual antibacterial action. The S_CM‐RBC formula showed strong antibiofilm activity, excellent mechanical strength, and biosafety. It effectively controlled oral bacteria in prevention of caries recurrence, and maintained pulp health in a rat ...
Chenmin Yao +11 more
wiley +1 more source
The Biological Effect of Platelet-Rich Plasma on Subacromial Bursa and Torn Supraspinatus Tendon: A Randomized Controlled Trial. [PDF]
Pitsilos C +5 more
europepmc +1 more source
Covalent Reprogramming of Kinase Binders to Modulate Protein Abundance
Electrophilic remodeling of a broad‐spectrum kinase binder reveals how subtle chemical changes reprogram protein fate. An acrylamide analog of a multi‐kinase binder selectively stabilizes Aurora kinase A (AURKA) by suppressing its ubiquitination, while a short‐linker variant converts this stabilizer into a degrader.
Chen Mozes +4 more
wiley +1 more source

