Results 51 to 60 of about 73,287 (260)

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source

Assessing the Performance of a Citizen Science Based Water Quality Monitoring Program for Nitrates Using Test Strips Implemented in the Medjerda Hydrosystem in Northern Tunisia

Hydrology
Recent technological progress in water management of hydrosystems has been made to deploy efficient and effective water quality monitoring systems (WQMS).
Safa Chaabane, Khalifa Riahi, Slaheddine Khlifi, Emna Slama, Marnik Vanclooster   +4 more
doaj   +1 more source

Analysis of the application of path finding system based on efficiency improvement in smart tourism

Intelligent Systems with Applications, 2023
With the proposal and development of intelligent tourism destination, the problem of tourism route planning has become a hot topic in tourism research.
Shuping Liu, Hao Wu
doaj   +1 more source

Generalized Maneuvers in Route Planning [PDF]

, 2012
We study an important practical aspect of the route planning problem in real-world road networks -- maneuvers. Informally, maneuvers represent various irregularities of the road network graph such as turn-prohibitions, traffic light delays, round-abouts, forbidden passages and so on.
Petr Hlinený, Ondrej Moris
openaire   +2 more sources

High Health Care Utilization Preceding Diagnosis With Juvenile Idiopathic Arthritis

Arthritis Care &Research, EarlyView.
Objective Although early diagnosis improves long‐term outcomes, patients with juvenile idiopathic arthritis (JIA) often experience prolonged, circuitous paths to diagnosis. To inform diagnostic improvement, we sought to characterize health care utilization in the year preceding diagnosis. Methods We identified 10,021 patients with an incident diagnosis
Anna Costello, Rui Xiao, Xuemei Zhang, Jahan Jazayeri, Irit R. Rasooly, Pamela F. Weiss   +5 more
wiley   +1 more source

Hierarchical Route Planning Framework and MMDQN Agent-Based Intelligent Obstacle Avoidance for UAVs

Drones
Efficient route planning technology is the core support for ensuring the successful execution of unmanned aerial vehicle (UAV) flight missions. In this paper, the coordination issue of global route planning and local real-time obstacle avoidance in ...
Boyu Dong, Yuzhen Zhang, Peiyuan Yuan, Shuntong Lu, Tao Huang, Gong Zhang   +5 more
doaj   +1 more source

Route planning of unmanned aerial vehicle in post-disaster underground based on improved algorithm

Gong-kuang zidonghua, 2018
In view of problems of redundant search point and poor real-time performance when encountering sudden threat existed in application of traditional algorithm in route planning of unmanned aerial vehicle in environment detection for post-disaster ...
LYU Wenhong, XIA Shuangshuang, WEI Bowen, YIN Lijie, GUO Yinjing   +4 more
doaj   +1 more source

A Numerical–Experimental Approach for Multi‐Matrix Fiber‐Reinforced Plastics Characterization Using Finite Element Model Updating

Advanced Engineering Materials, EarlyView.
A numerical–experimental framework is developed for characterizing multi‐matrix fiber‐reinforced polymers (MM‐FRPs) combining epoxy and polyurethane matrices. Harmonic bending tests are integrated with finite element model updating (FEMU) to simultaneously identify elastic and viscoelastic material parameters.
Rodrigo M. Dartora, Tales V. Lisbôa, Axel Spickenheuer, Rogério J. Marczak, Jakson M. Vassoler   +4 more
wiley   +1 more source

Towards Defect Phase Diagrams: From Research Data Management to Automated Workflows

Advanced Engineering Materials, EarlyView.
A research data management infrastructure is presented for the systematic integration of heterogeneous experimental and simulation data required for defect phase diagrams. The approach combines openBIS with a companion application for large‐object storage, automated metadata extraction, provenance tracking and federated data access, thereby supporting ...
Khalil Rejiba, Sang‐Hyeok Lee, Christina Gasper, Martina Freund, Sandra Korte‐Kerzel, Ulrich Kerzel   +5 more
wiley   +1 more source