Results 31 to 40 of about 3,015,205 (202)

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Journey planning based on user needs [PDF]

open access: yes, 2007
In this paper we discuss potential developments to the design of pre-trip in-home journey planning services, to include support for additional user needs.
André, Paul   +7 more
core   +2 more sources

Assessing the Performance of a Citizen Science Based Water Quality Monitoring Program for Nitrates Using Test Strips Implemented in the Medjerda Hydrosystem in Northern Tunisia

open access: yesHydrology
Recent technological progress in water management of hydrosystems has been made to deploy efficient and effective water quality monitoring systems (WQMS).
Safa Chaabane   +4 more
doaj   +1 more source

Route planning module as a part of Supply Chain Management system

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2012
Today, the demand for creating a systematic approach for managing sales, ordering, and logistics has increased. Supply Chain Management (SCM) is one of the responses to problems that have arose with the need for managing complex supply chains.
Michal Košíček   +4 more
doaj   +1 more source

A Systematic Space-Time Route Planning Approach Coordinated With Task Assignment for Autonomous Delivery Vehicles Fleet

open access: yesIEEE Access, 2023
With the development and maturity of autonomous driving technology, parcel terminal distribution has taken the lead as an application scenario for unmanned delivery vehicles that autonomously perform the task of delivering packages between distribution ...
Jianqiang Wang   +3 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Landing route planning method for micro drones based on hybrid optimization algorithm

open access: yesBiomimetic Intelligence and Robotics, 2021
Aiming at the obstacle avoidance trajectory planning problem in the landing process of the micro drone, this paper proposes a swarm optimization algorithm that combines the dragonfly optimization method and the differential evolution method.
Shaoran Liang, Bifeng Song, Dong Xue
doaj   +1 more source

Communication-Oriented and Process Sensitive Planning Support [PDF]

open access: yes, 2020
The complexity of the planning context has raised criticism against public participation for being a rigid top-down endeavour which does not recognize the different communicative needs and necessary working modes in the engagement of broad publics and ...
Staffans, Aija   +5 more
core   +2 more sources

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

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