Results 61 to 70 of about 34,561 (298)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Simulación de Redes de Sensores Inalámbricos: un Modelo Energético a Nivel de Nodo-Sensor Bajo las Especificaciones Ieee 802.15.4tm y Zigbee

open access: yesPublicaciones e Investigación, 2015
Este artículo presenta el desarrollo de un modelo de simulación para una red de sensores inalámbricos que se rige por las especificaciones IEEE 802.15.4 y ZigBee y que utiliza la configuración de la beacon habilitada.
Milton Osvaldo Amarillo Rojas   +1 more
doaj   +1 more source

Fault-Tolerant Network-On-Chip Router Architecture Design for Heterogeneous Computing Systems in the Context of Internet of Things

open access: yesSensors, 2020
Network-on-chip (NoC) architectures have become a popular communication platform for heterogeneous computing systems owing to their scalability and high performance.
Muhammad Rashid   +6 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Coverage and Routing Optimization of Wireless Sensor Networks Using Improved Cuckoo Algorithm

open access: yesIEEE Access
Wireless sensor networks have gradually attracted widespread attention from academia and industry due to their wide application potential and versatility. In response to the coverage and routing issues of wireless sensor networks, this study combines the
Jian Yang, Yimin Xia
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Router-based network traffic observation by terminal sliding mode control theory

open access: yes, 2018
Since the early days of the Internet, network traffic monitoring (NTM) has always played a strategic role in understanding and characterizing users’ activities.
Long Xu (218743)
core   +1 more source

Security in Internet [PDF]

open access: yesInformatică economică, 2006
A very good method that can be used to protect a private network is the implementation of a firewall between Internet and Intranet. This firewall will filter the packets that transit the network according with the security policy defined at the system ...
Felician ALECU
doaj  

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