Results 111 to 120 of about 3,392,111 (365)
ICBT in routine care: A descriptive analysis of successful clinics in five countries
Clinical trials have demonstrated the efficacy of internet delivered cognitive behaviour therapy (ICBT) for anxiety and depression. However, relatively little is known about the context, operations, and outcomes of ICBT when administered as part of ...
N. Titov +16 more
semanticscholar +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Selective versus routine use of episiotomy for vaginal birth
Background Some clinicians believe that routine episiotomy, a surgical cut of the vagina and perineum, will prevent serious tears during childbirth. On the other hand, an episiotomy guarantees perineal trauma and sutures. Objectives To assess the effects
Hong Jiang +3 more
semanticscholar +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
21st Century Televisuality? Golden Ages and Collateral Damage in Industry Stress Research
This article examines how the innovations of, and fallout from, the post-1980s US multichannel cable era both prefigured and were transformed by the 21st-century online platform streaming era.
John T. Caldwell
doaj +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
reservedL'elaborato prende spunto dall'attività di tirocinio, svolta durante l'ultimo anno accademico, in cui ho avuto l'occasione di verificare le mie conoscenze e mettere alla prova le mie capacità formative-relazionali.
NUNZIATO, FRANCESCA
core
Comparison of Routine Histopathological Examination Results in Children and Adults After Tonsillectomy and/or Adenoidectomy [PDF]
Objective:Tonsillectomy and/or adenoidectomy is one of the most common otolaryngologic surgical procedures. There is still an ongoing debate as to whether or not histopathological examination should be performed in which cases after these surgeries.
Ceyhun Aksakal, Ahmet Müslehiddinoğlu
core +1 more source
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Non-routine problem solving and strategy flexibility: A quasi-experimental study
This study aims to determine the effect of an instruction dealing with non-routine problem solving on fifth graders' strategy flexibility and success in problem-solving.
Yeliz Yazgan +5 more
core +1 more source

