Results 121 to 130 of about 3,043,735 (316)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Validation of a long-read 16S rRNA-gene sequencing approach for analysis of clinical samples and bacterial identification in a routine clinical laboratory

Frontiers in Microbiology
BackgroundCurrently, microbiological diagnosis relies heavily on classical culture-based techniques, which have notable limitations. These methods often struggle with detecting non-culturable or slow-growing microorganisms and can yield negative results ...
Otto Van de gaer, Reinoud Cartuyvels, Timo Froyen, Petra Hilkens, Koen Magerman, Koen Magerman, Steven Martens, Britt Van Meensel, Jozef Dingemans   +8 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Overall Survival Results of a Trial Assessing Patient-Reported Outcomes for Symptom Monitoring During Routine Cancer Treatment

Journal of the American Medical Association (JAMA), 2017
E. Basch, A. Deal, A. Dueck, H. Scher, M. Kris, C. Hudis, D. Schrag   +6 more
semanticscholar   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Barriers to routine childhood vaccination during COVID-19: Lessons from a primary healthcare study in Greece

Vaccine: X
Background: The COVID-19 pandemic has disrupted childhood vaccination programs globally. This study aimed to evaluate the impact of the pandemic on routine childhood vaccinations in primary care settings in Greece, specifically in an area with ...
Marinetta Bakea, Despoina Gkentzi, Chrysoula Perdikogianni, Eleni Vergadi   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Energy-dense versus routine enteral nutrition in critically ill patients: a systematic review and meta-analysis

Frontiers in Nutrition
Background and aimCritically ill patients often experience low target attainment rates with enteral nutrition (EN), leading to malnutrition and poor clinical outcomes.
Zonghong Zhang, Zonghong Zhang, Chuanlai Zhang, Chuanlai Zhang, Huiling Pan, Huiling Pan, Ruiqi Yang, Ruiqi Yang, Yin Fang, Yin Fang   +9 more
doaj   +1 more source

Symptom Monitoring With Patient-Reported Outcomes During Routine Cancer Treatment: A Randomized Controlled Trial.

Journal of Clinical Oncology, 2016
E. Basch, A. Deal, M. Kris, H. Scher, C. Hudis, P. Sabbatini, L. Rogak, A. Bennett, A. Dueck, T. Atkinson, J. Chou, Dorothy Dulko, L. Sit, A. Barz, P. Novotny, M. Fruscione, J. Sloan, D. Schrag   +17 more
semanticscholar   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source