Results 121 to 130 of about 2,355,447 (305)

Using clinical records to evaluate family intervention for psychosis in routine practice [PDF]

, 2019
Objectives: This study sought to evaluate family intervention (FI) for psychosis that had been offered in routine practice by a dedicated FI service. Method: A retrospective analysis of electronic clinical records was undertaken to examine those who ...
Chuttoo, L., Allen, J., Griffiths, M.
core  

Barriers to routine childhood vaccination during COVID-19: Lessons from a primary healthcare study in Greece

Vaccine: X
Background: The COVID-19 pandemic has disrupted childhood vaccination programs globally. This study aimed to evaluate the impact of the pandemic on routine childhood vaccinations in primary care settings in Greece, specifically in an area with ...
Marinetta Bakea, Despoina Gkentzi, Chrysoula Perdikogianni, Eleni Vergadi   +3 more
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Energy-dense versus routine enteral nutrition in critically ill patients: a systematic review and meta-analysis

Frontiers in Nutrition
Background and aimCritically ill patients often experience low target attainment rates with enteral nutrition (EN), leading to malnutrition and poor clinical outcomes.
Zonghong Zhang, Zonghong Zhang, Chuanlai Zhang, Chuanlai Zhang, Huiling Pan, Huiling Pan, Ruiqi Yang, Ruiqi Yang, Yin Fang, Yin Fang   +9 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

„Oszillieren“ zwischen Kreativität und Routine? Zur körperlichen Performativität des Kreativen im alltäglichen Fremdsprachenunterricht

TIPA. Travaux interdisciplinaires sur la parole et le langage
Das Verhältnis von Kreativität und Routine bleibt in fremdsprachendidaktischen Publikationen eher unscharf und wird mit Oszillieren beschrieben. Fremdsprachendidaktischen Erwartungen an kreativen, körperlich aktivierenden (Literatur-)Unterricht stellt ...
Matthias Grein
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Proving Bone Marrow Plasma Cell Clonality by Flow Cytometry: An Important Tool in the Diagnosis of Immunoglobulin Light-Chain Amyloidosis

Biomedicines
Background/Objectives: Light-chain amyloidosis (AL Amyloidosis) is a rare systemic plasma cell disorder in which misfolded light chains form amyloid fibrils that damage vital organs. Diagnosis is often delayed because of variable presentation and overlap
Sorina Nicoleta Badelita, Horia Mihail Sandu, Daniel Coriu, Andreea Jercan, Sinziana Barbu, Larisa Zidaru, Mihai Emanuel Himcinschi, Camelia Dobrea, Monica Popescu, Delia Codruta Popa   +9 more
doaj   +1 more source

Anything But Routine [PDF]

Academic Pediatrics, 2020
openaire   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source