Results 71 to 80 of about 3,803,647 (352)

The causes and circumstances of drinking water incidents impact consumer behaviour:Comparison of a routine versus a natural disaster incident [PDF]

open access: yes, 2014
When public health is endangered, the general public can only protect themselves if timely messages are received and understood. Previous research has shown that the cause of threats to public health can affect risk perception and behaviours.
Blendon   +16 more
core   +2 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

The routine pre-employment screening chest radiograph: Should it be routine?

open access: yesIndian Journal of Radiology and Imaging, 2016
Background and Objective: A routine chest radiograph is mandatory in many institutions as a part of pre-employment screening. The usefulness of this has been studied over the years keeping in mind the added time, cost, and radiation concerns.
John Samuel V   +2 more
doaj   +1 more source

Routine characterization and interpretation of complex alkali feldspar intergrowths [PDF]

open access: yes, 2015
Almost all alkali feldspar crystals contain a rich inventory of exsolution, twin, and domain microtextures that form subsequent to crystal growth and provide a record of the thermal history of the crystal and often of its involvement in replacement ...
Fitz Gerald, John D.   +2 more
core   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Routinegedrag in de ouderdom. Onderzoek met de Schaal van Voorkeur voor Routine

open access: yesTijdschrift voor Gerontologie en Geriatrie, 2012
Hoewel iedereen weet wat een door routine gekenmerkte levenswijze is en hoewel deze levenswijze zelfs als een veelvoorkomend gedrag van oudere mensen wordt beschouwd, is dit fenomeen toch weinig wetenschappelijk onderzocht.
J. Bouisson, L. Avinen-Vanhaeren
doaj   +1 more source

Eigenvalue routine by Sturm sequence method [PDF]

open access: yes, 1973
Computer program has been generated for efficient solution of certain broad classes of eigenvalue problems. Procedure fully exploits banded nature of associated matrices and further enables user to compute either all roots or any specific ones desired ...
Gupta, K. K.
core   +1 more source

Randomised controlled trial and economic evaluation of a chest pain observation unit compared with routine care [PDF]

open access: yes, 2004
Objectives To measure the effectiveness and cost effectiveness of providing care in a chest pain observation unit compared with routine care for patients with acute, undifferentiated chest pain.
Angelini, K.   +11 more
core   +2 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

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