Results 81 to 90 of about 3,392,111 (365)

Ethical issues of routine universal screening [PDF]

open access: yes, 1992
Few diseases have raised as many ethical questions as AIDS and HIV infection. One of these questions concerns the use of blood tests to identify individuals infected with HIV.
Agius, Emmanuel   +1 more
core  

When routine screening is not routine

open access: yesThe International Journal of Whole Person Care, 2022
In our current environment of value based care and payment models, greater emphasis is placed on completing evidence based, routine screening tests for patients. While there is clear preventive health benefit, population based initiatives may overlook opportunities to prepare individual patients for possible abnormal results.
openaire   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

Routine job dynamics in the Swiss labor market [PDF]

open access: yes, 2022
I investigate the role of labor market flows in the decline of routine employment in Switzerland between 1992 and 2018 using rich individual-level panel data from the Swiss Labour Force Survey.
Gschwendt, Christian   +1 more
core   +1 more source

Dietary Protein Intake and Peritoneal Protein Losses in Peritoneal Dialysis Patients

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) patients lose protein in their waste dialysate, potentially increasing their risk for malnutrition. We wished to determine whether there was any association between losses and dietary protein intake (DPI). Methods DPI was assessed from 24‐h dietary recall using Nutrics software.
Haalah Shaaker, Andrew Davenport
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Pre- performance routines followed by free throw shooting accuracy in secondary basketball players

open access: yesBiomedical Human Kinetics, 2015
Study aim: The purpose of the current study was to determine whether existing pre-performance routines had an effect on free throw shooting accuracy in high school pupils as compared to shooting without a pre-performance routine.
Phelps Ashley, Kulinna Pamela
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Routine Microsecond Molecular Dynamics Simulations with AMBER on GPUs. 1. Generalized Born

open access: yesJournal of Chemical Theory and Computation, 2012
We present an implementation of generalized Born implicit solvent all-atom classical molecular dynamics (MD) within the AMBER program package that runs entirely on CUDA enabled NVIDIA graphics processing units (GPUs).
A. Götz   +5 more
semanticscholar   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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