Results 71 to 80 of about 2,355,447 (305)

Overnight Dexamethasone Suppression Test in the Diagnosis of Cushing's Disease

open access: yesActa Medica Iranica, 2010
Realizing the cause of Cushing's Syndrome (CS) is one of the most challenging processes in clinical endocrinology. The long high dose dexamethasone suppression test (standard test) is costly and need an extended inpatient stay.
Fatemeh Esfahanian, Rozana Kazemi
doaj  

An evaluation of a referral management and triage system for oral surgery referrals from primary care dentists: a mixed-methods study

open access: yesHealth Services and Delivery Research, 2018
Background: Oral surgery referrals from dentists are rising and putting increased pressure on finite hospital resources. It has been suggested that primary care specialist services can provide care for selected patients at reduced costs and similar ...
Joanna Goldthorpe   +7 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Routine examination of the newborn: the EMREN study. Evaluation of an extension of the midwife role including a randomised controlled trial of appropriately trained midwives and paediatric senior house officers. [PDF]

open access: yes, 2004
OBJECTIVES: To assess the implications and cost-effectiveness of extending the role of midwives to include the routine (24-hour) examination of the healthy newborn usually carried out by junior doctors. DESIGN: The study included a prospective randomised
Tomlin, M.   +27 more
core   +1 more source

Leisure Traveling for 21st Century Americans: Mass Tourism as a Cultural Trap

open access: yesAmerican, British and Canadian Studies Journal, 2014
The majority of mass men in the American environment exhibit predictable and similar patterns of behavior as tourists. Pre-Industrial Revolution modes of traveling as liberation and exploration are now thwarted by the leveling effect of globalization and
Aniculăese Ovidiu
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

A systematic review on repetition rate of routine digital radiography [PDF]

open access: yes, 2017
Background: Repetition of radiograph is a critical event in routine digital radiography. High repetition rate also consumes equipment life time, increases operational cost, decreases patient satisfaction, increase world load and dose of radiation to the ...
Kadir @ Shahar, Hayati   +5 more
core   +1 more source

ESTIMATION OF COMPETITIVE ACTIVITY IN SYNCHRONIZED SWIMMING

open access: yesPhysical Education of Students, 2013
Aim – is to develop the approach to technical complexity estimation of free routine composition in synchronized swimming. Were analyzed and considered free routine compositions of the strongest swimmers in European and World Championships during the ...
L.M. Shul'ga, T.I. Rudkovskaya
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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