Advanced Science, EarlyView.We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang +11 more
wiley +1 more source
Automated Flushing System for Post-Processing in Microfluidic Device Fabrication. [PDF]
Micromachines (Basel)Zapata S +4 more
europepmc +1 more source
Enzymatic DNA Reaction Networks for Orchestrating Stimuli‐Dependent Temporal Molecular Pulse
Advanced Science, EarlyView.We present an enzymatic DNA reaction network (EDRN) that encodes nucleic‐acid targets in time, converting inputs into a universal strand and then into programmable transient fluorescence pulses. With time‐color multiplexing, EDRN enables single‐tube high‐plex nucleic acid detection and shows strong agreement with clinical sequencing across 32 specimens.
Jiayu Yang +7 more
wiley +1 more source
Obstacle-avoiding routing algorithm for redistribution layer
, 2016 碩士重分佈層(RDL,Redistribution Layer)目前多使用在覆晶技術(Flip-Chip)上，而覆晶技術是一種將IC與基板(substrate)相互連接，基於小尺寸晶片、高I/O密度的封裝(Packging)方法。在封裝的過程中，先將晶片的墊片(pad)長出凸塊(bump)，然後將其翻覆過來，以面朝下的方式讓晶片上的墊片透過金屬導體與基板的接合點相互連接的封裝技術。 然而，覆晶技術最初的I/O接點並不具有面陣列(area array)的設計，使得此技術在早期受到不小的阻礙 ...
王偉丞;Wang, Wei-Cheng
core
LightIN: a versatile silicon-integrated photonic field programmable gate array with an intelligent configuration framework for next-generation AI clusters. [PDF]
Light Sci ApplZhu Y +16 more
europepmc +1 more source
Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro
Advanced Science, EarlyView.The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel +15 more
wiley +1 more source
, 2010 碩士隨著超大型積體電路製程的日益進步，晶片設計早就已經無法單純的靠人力完成，電路的複雜度是一個很重要的主因，為了處理高複雜度的設計，所以有了電子設計自動化的產生，大幅降低從擬定規格到設計定案的時間，也節省了許多人力上的付出。 在現在的奈米世代中，一個超大型積體電路晶片可能包含了幾百萬個電晶體，導致在佈局階段將有幾千萬條線必須完成繞線，繞線的問題變的越來越複雜，必須在有限的繞線區域內完成所有的繞線，否則必須退回到之前的步驟重新擺置所有元件，調整出更適合的繞線區域 ...
林奕辰; Lin, Yi-chen
core
Development and simulation of an innovative autonomous knowledge-based smart waste collection system. [PDF]
Sci RepAbdallah M, Hosny M.
europepmc +1 more source
Machine‐Learning Microfluidic Minute‐Scale Microorganism Metrics Monitoring(M6)
Advanced Science, EarlyView.ABSTRACT On‐site monitoring of microorganisms remains challenging because of low concentrations, strong background interference, and dynamic aerosol diffusion, particularly for aerosol‐transmitted pathogens. Here, we report a rapid detection platform that integrates a Puri‐focusing microfluidic chip, electrochemical impedance spectroscopy (EIS), and ...
Ning Yang +14 more
wiley +1 more source
mSIGMA: A Multilevel Full-Chip Routing System Considering SIGnal-integrity and MAnufacturability
, 2007 由於超大型積體電路技術的快速發展，晶片設計已經到達奈米製程的時代。但在奈米晶片實體設計中，繞線(routing)所造成的問題佔整體晶片設計效能的比例卻逐漸增加且面臨到許多問題，尤其是(1)設計複雜度、(2)訊號完整度(signal-integrity)及(3)製造度(manufacturability)等三大問題急需去處理。因此，本篇論文提出了一創新的多階層繞線器(mSIGMA)來解決訊號完整度及可製造度等問題。 早期的繞線問題是使用直接兩階段繞線方式(flat routing)，也就是全域繞線 ...
何宗易, Ho, Tsung-Yi
core