Results 151 to 160 of about 566,058 (355)

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

open access: yesAdvanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson   +12 more
wiley   +1 more source

Perfusable Brain Microvascular Network‐On‐Chip Model to Study Flavivirus NS1‐Induced Endothelial Dysfunction

open access: yesAdvanced Functional Materials, EarlyView.
This study presents a microfluidic brain microvascular network‐on‐chip (BMVasChip) to investigate endothelial barrier dysfunction caused by flavivirus non‐structural protein 1 (NS1), including virus‐ and time‐dependent vascular damage, leakiness, and dysfunction.
Monika Rajput   +5 more
wiley   +1 more source

Fluoride‐Free Molten Salt Hydrate‐Assisted Synthesis of MXene in Air Down to 150 °C

open access: yesAdvanced Functional Materials, EarlyView.
A novel low‐temperature shielded salt (LSS) approach enables the synthesis of MXenes in air at temperatures as low as 150 °C using MgCl2·6H2O/LiCl. This method demonstrates successful etching of challenging MXenes like Cr2CTx and Nb2CTx through the synergistic effects of Li+ ions and salt hydrate phase changes, while eliminating the need for inert ...
Sin‐Yi Pang   +7 more
wiley   +1 more source

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang   +9 more
wiley   +1 more source

The AODV Routing Protocol based on Location Information for Inter-Vehicle Communication [PDF]

open access: bronze, 2008
Eun‐Ju Lee   +3 more
openalex   +1 more source

Cholesterol in mRNA‐Lipid Nanoparticles can be Replaced with the Synthetic Mycobacterial Monomycoloyl Glycerol Analogue MMG‐1

open access: yesAdvanced Functional Materials, EarlyView.
This study demonstrates that cholesterol in messenger RNA‐lipid nanoparticles (mRNA‐LNPs) can be completely replaced with an immunopotentiating lipid, i.e., a synthetic analogue of the C‐type lectin receptor agonist monomycoloyl glycerol (MMG‐1), without compromising physicochemical properties, in vivo transfection efficiency, and immunogenicity of the
Abhijeet G. Lokras   +19 more
wiley   +1 more source

CAIR: Using Formal Languages to Study Routing, Leaking, and Interception in BGP

open access: yes, 2016
The Internet routing protocol BGP expresses topological reachability and policy-based decisions simultaneously in path vectors. A complete view on the Internet backbone routing is given by the collection of all valid routes, which is infeasible to obtain
Biersack, Ernst W.   +4 more
core  

Reconfigurable Three‐Dimensional Superconducting Nanoarchitectures

open access: yesAdvanced Functional Materials, EarlyView.
3D superconducting nanostructures offer new possibilities for emergent physical phenomena. However, fabricating complex geometries remains challenging. Here 3D nanoprinting of complex 3D superconducting nanoarchitectures is established. As well as propagating superconducting vortices in 3D, anisotropic superconducting properties with geometric ...
Elina Zhakina   +11 more
wiley   +1 more source

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