Results 51 to 60 of about 16,697,239 (278)

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Entanglement Routing in Quantum Networks: A Comprehensive Survey

IEEE Transactions on Quantum Engineering
Entanglement routing in near-term quantum networks consists of choosing the optimal sequence of short-range entanglements to combine through swapping operations to establish end-to-end entanglement between two distant nodes.
Amar Abane, Michael Cubeddu, Van Sy Mai, Abdella Battou   +3 more
doaj   +1 more source

Smart Routing Management Framework Exploiting Dynamic Data Resources of Cross-Layer Design and Machine Learning Approaches for Mobile Cognitive Radio Networks: A Survey

IEEE Access, 2020
The concept of Cognitive Radio (CR) has emerged as a practical solution to solve the issue of the fixed spectrum and bandwidth scarcity in wireless communication.
Qusay Medhat Salih, Md. Arafatur Rahman, Fadi Al-Turjman, Zafril Rizal M. Azmi   +3 more
doaj   +1 more source

Design of a Self-Organizing Routing Protocol for Underwater Wireless Sensor Networks Based on Location and Energy Information

Journal of Marine Science and Engineering, 2023
Underwater wireless sensor networks (UWSNs) are significantly different from terrestrial sensor networks in the following aspects: low bandwidth, high latency, variable topology, limited battery, low processing power and so on.
Weizhen Guo, Min Zhu, Bo Yang, Yanbo Wu, Xinguo Li   +4 more
doaj   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Reinforcement Learning-Based Routing Protocol to Minimize Channel Switching and Interference for Cognitive Radio Networks

Complexity, 2020
In the existing network-layered architectural stack of Cognitive Radio Ad Hoc Network (CRAHN), channel selection is performed at the Medium Access Control (MAC) layer. However, routing is done on the network layer.
Tauqeer Safdar Malik, Mohd Hilmi Hasan
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

HPIM‐DM: A fast and reliable dense‐mode multicast routing protocol

IET Networks, 2023
The Hard‐state Protocol Independent Multicast—Dense Mode (HPIM‐DM) multicast routing protocol is proposed. HPIM‐DM is a hard‐state version of PIM‐DM that overcomes its poor convergence times and lack of resilience to replay attacks.
Pedro Oliveira, Alexandre Silva, Rui Valadas   +2 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Performance Evaluation of Routing Metrics in the LOADng Routing Protocol

Journal of Communications Software and Systems, 2017
LOADng (Lightweight On-demand Ad hoc Distance-vector Routing Protocol - Next Generation) is an emerging routing protocol that emerged as an alternative to RPL (IPv6 Routing Protocol for Low power and Lossy Networks). Although some work has been dedicated
Jose V. V. Sobral, Joel J. P. C. Rodrigues, Neeraj Kumar, Chunsheng Zhu, Raja W. Ahmad   +4 more
doaj