Results 51 to 60 of about 173,590 (277)

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Performance Analysis of DTN Using Level Signal Priority Epidemic Routing Protocol

open access: yesEmitter: International Journal of Engineering Technology, 2016
A DTN architecture consists of several nodes that are connected with high dynamic topology. The routing protocol is an important part which determine the DTN performance system.
Ahmad Zainudin   +2 more
doaj   +3 more sources

ANALISIS PERBANDINGAN ROUTING PROTOKOL OPEN SHORTES PATH FIRST (OSPF) DENGAN ENHANCED INTERIOR GATEWAY ROUTING PROTOCOL (EIGRP)

open access: yesIlkom Jurnal Ilmiah, 2018
Routing adalah proses pemilihan rute terbaik untuk suatu paket data agar dapat sampai ke tujuannya. Proses routing sangat dibutuhkan dalam proses pengiriman  data.
Nur Indah, Yulita Salim, Ramdan Satra
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Using the redistribution between routing protocols to find best route

open access: yesمجلة علوم ذي قار, 2019
Routers can forward packets through an internetwork by maintaining routing information in a database called a routing table. The routing table typically contains the address of all known networks and routing information about that network such as ...
Aqeel Hamad
doaj  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Adaptive link-weight routing protocol using cross-layer communication for MANET [PDF]

open access: yes, 2007
Routing efficiency is one of the challenges offered by Mobile Ad-hoc Networks (MANETs). This paper proposes a novel routing technique called Adaptive Link-Weight (ALW) routing protocol.
Al-Khwildi, AN   +3 more
core   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Fuzzy Logic-Based Geographic Routing Protocol for Dynamic Wireless Sensor Networks

open access: yesSensors, 2019
The geographic routing protocol only requires the location information of local nodes for routing decisions, and is considered very efficient in multi-hop wireless sensor networks.
Xing Hu   +5 more
doaj   +1 more source

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