Results 181 to 190 of about 3,625,328 (233)

Nasal High-Flow Therapy: Role of F i O2 in the ROX Index

open access: yesAmerican Journal of Respiratory and Critical Care Medicine, 2019
openaire   +2 more sources

Sleep Deprivation Induces Glial Dysfunction, Synaptic Loss, Metabolic Imbalance, and Cognitive Impairment in 12‐Month‐Old Mice: Protective Effects of D30

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Sleep deprivation induces neuroglial atrophy and dendritic spine loss, accompanied by metabolic disturbances involving 1‐methyladenosine, citric acid, L‐kynurenine, and berberine, indicating disrupted neuroenergetic and immunometabolic homeostasis. These alterations result in deficits in spatial recognition, fear conditioning, nesting, and Morris Water
Xueyan Liu   +9 more
wiley   +1 more source

Genetic (Genomic) and Morphological Evidence Suggest That the Korean Endemic Fat Minnow (Rhynchocypris kumgangensis) and the Deogyu Population Represent Distinct Species

open access: yesEcology and Evolution, Volume 16, Issue 9, September 2026.
Clear genetic and morphological divergence were revealed between the two Korean endemic 'putative' species Rhynchocypris kumgangensis and the Deogyu population (R. deogyuensis) using an integrated analysis of molecular markers, mitogenomes, and geometric and morphometrics on body shape.
Soon Young Hwang   +3 more
wiley   +1 more source

Temporal Replication and Sampling Efficiency in High‐Frequency Autonomous and Manual eDNA Sampling

open access: yesEnvironmental DNA, Volume 8, Issue 5, September‐October 2026.
Accounting for temporal correlation in eDNA time series can improve the accuracy of ecological inference about the influence of hydrological covariates on eDNA concentration. Further, we found that MCE filters were more efficient than PES filters. ABSTRACT Environmental DNA (eDNA) sampling is a valuable tool for ecological research, but its reliability
Ben C. Augustine   +6 more
wiley   +1 more source

AKT, ATR, and Notch Inhibitors Radiosensitize a Preclinical Model of Adenoid Cystic Carcinoma

open access: yesHead &Neck, Volume 48, Issue 9, Page 2364-2376, September 2026.
ABSTRACT Background Adenoid Cystic Carcinoma (ACC) is a rare and lethal type of head and neck cancer. Standard therapy involves surgery followed by radiation therapy. The majority of ACC has MYB overexpression and MYB‐NFIB gene fusions, while Notch mutations are associated with aggressive behavior.
Shivani Thoidingjam   +10 more
wiley   +1 more source

Nanoplastic Particle Exposure Induces Toxicity and Amplifies Cellular Stress in THP‐1 Macrophages: Insights on Molecular Pathways and Circulating Proteome Interaction

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Polystyrene nanoplastic particles (NPPs) interact with serum proteins, establishing nano‐bio interactions and triggering ROS‐mediated macrophage toxicity in THP‐1 cells, characterized by oxidative stress, mitochondrial dysfunction, apoptosis and stress‐signaling.
Balamurali Mahalakshmi   +3 more
wiley   +1 more source

Fibroblast Activation Protein Expression Differs Between Inflamed and Fibrostenotic Inflammatory Bowel Disease

open access: yesJCC Plus, Volume 1, Issue 5, September 2026.
This study demonstrates that fibroblast activation protein expression is elevated in inflamed and fibrostenotic inflammatory bowel disease, with highest levels in fibrostenotic Crohn's disease. Cellular fibroblast activation protein predominates in inflamed tissues and localises to α‐SMA−PDPN−CD90+ stromal cells. ABSTRACT Background Intestinal fibrosis
Dalia A. Lartey   +14 more
wiley   +1 more source

Development of the Novel FLOX Score to Assess Risk of Intubation in Children With Immunocompromising Conditions Receiving High Flow Nasal Cannula

open access: yesPediatric Pulmonology, Volume 61, Issue 9, September 2026.
ABSTRACT Background Heated, humidified, high‐flow nasal cannula (HFNC) before intubation has been associated with increased mortality in children with immunocompromising conditions (ICC). Objectives We sought to describe HFNC failure (intubation) rate and aimed to develop a novel score associated with HFNC failure.
Michelle A. Mai   +2 more
wiley   +1 more source

Optimization of antibody binding by adjusting thermodynamic stability during the maturation of antibody affinities

open access: yesProtein Science, Volume 35, Issue 9, September 2026.
Abstract Somatic mutations and antibody clone selection occur in B‐cell hyper‐evolution over extremely brief periods of time. Herein, we developed a technique for antibody screening by immunizing alpacas with antigens and observing antibody sequence transitions over time, a method we named Tracking the Evolution of Antibodies over time.
Yoko Akazawa‐Ogawa   +7 more
wiley   +1 more source

Genomic resources to advance seed coat color and patterning genetics and breeding in common bean (Phaseolus vulgaris L.)

open access: yesThe Plant Genome, Volume 19, Issue 3, September 2026.
Abstract Seed coat color and patterning are key quality traits in common bean (Phaseolus vulgaris L.) that define market classes and strongly influence consumer preference and market value. These traits are controlled by a complex network of major genes (sometimes with epistatic interactions), which complicates the recovery of desired market class ...
Jayanta Roy   +5 more
wiley   +1 more source

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