Results 41 to 50 of about 160,344 (254)

Board Structure and ESG Outcomes: A Comprehensive Review and Pathways for Future Research

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT This study provides a comprehensive systematic review of 265 scholarly articles that examine the relationship between board diversity and environmental, social and governance (ESG) practices. The analysis critically maps existing research and identifies key thematic trends, revealing that most studies focus on gender and independence while ...
Karim Mahran   +3 more
wiley   +1 more source

Tetrazine Ligation in Living Systems: Beyond Fast Kinetics to Effective Bioorthogonality

open access: yesChemistry – A European Journal, EarlyView.
Rapid reaction kinetics (k2) alone do not ensure successful tetrazine ligation in living systems. This review introduces ‘effective orthogonality’—focusing on chemical survival, availability, and encounter—as a practical framework. We highlight how bottlenecks shift from cellular sinks to in vivo delivery limits, offering design strategies for reliable
Junhyeong Yim   +3 more
wiley   +1 more source

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 Genotype and Use of 5‐HT3 Receptor Antagonists: 2026 Update

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
5‐hydroxytryptamine type 3 (5‐HT3) receptor antagonists are used to treat nausea and vomiting and in the prevention of chemotherapy‐induced, radiation‐induced, and postoperative nausea and vomiting. Most of the 5‐HT3 receptor antagonists (i.e., ondansetron, tropisetron, dolasetron, palonosetron, and ramosetron) are metabolized by CYP2D6, but the extent
Claire Moore   +16 more
wiley   +1 more source

Resolving CYP2D6 Structural Complexity with Long‐Read Sequencing: Implications for Tamoxifen Precision Dosing in Thai Breast Cancer Patients

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Cytochrome P450 2D6 (CYP2D6)‐mediated bioactivation of tamoxifen to endoxifen is a key determinant of therapeutic efficacy in estrogen receptor‐positive breast cancer. In Asian populations, the high prevalence of structurally complex CYP2D6 alleles complicates conventional genotyping, limiting accurate genotype–phenotype correlation.
Usa Boonyuen   +9 more
wiley   +1 more source

Perceived importance and didactic difficulty of chemistry education: Insights from Czech teachers

open access: yesThe Curriculum Journal, EarlyView.
Abstract This empirical study examines how chemistry teachers in lower and upper secondary schools in the Czech Republic evaluate the content of the chemistry curriculum, focussing on its perceived importance and didactic difficulty. Based on a quantitative survey (N = 146), the study provides insight into the pedagogical content knowledge of ...
Jitka Lorenzová   +6 more
wiley   +1 more source

Structural Validity of a Short Form of the Eating Disorder Examination Questionnaire in Adolescents Diagnosed With an Eating Disorder

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This study aimed to assess the structural validity and readability of a brief 7‐item version of the Eating Disorder Examination Questionnaire (the EDE‐Q7) among adolescents. Method Latent variable analysis was used in a sample of 263 adolescents (age range = 13–17.99y) diagnosed with an eating disorder and recruited from treatment ...
Paul E. Jenkins   +7 more
wiley   +1 more source

Radical Listening as a Governance Innovation: Integrating Planetary Health and Community‐Led Forest Conservation in Indonesia

open access: yesEnvironmental Policy and Governance, EarlyView.
ABSTRACT While REDD+ prioritizes carbon sequestration, its narrow focus often overlooks forest‐health linkages critical to community well‐being. This paper examines the holistic model of Health in Harmony (HIH) and Alam Sehat Lestari (ASRI), which integrates forest conservation with healthcare through radical listening—a decolonial community engagement
Angie Hsu   +3 more
wiley   +1 more source

Addressing Barriers to Fair Community Participation in Mangrove Carbon Credit Projects: Insights From Thailand

open access: yesEnvironmental Policy and Governance, EarlyView.
ABSTRACT Thailand has announced ambitious plans to reduce greenhouse gas emissions, including a programme that allows private companies to earn carbon credits from protecting and restoring mangroves. In 2023, the Department of Marine and Coastal Resources (DMCR) began enrolling local communities and private firms in this scheme.
Danny Marks, Kittima Leeruttanawisut
wiley   +1 more source

Brief to the Canadian Radio Television and Television Commission (CRTC)

open access: yes, 1972
The Ontario Committee on the Status of Women, a grassroots feminist group, was established in 1970. Its purpose was to seek implementation in Ontario of the Recommendations of the Royal Commission on the Status of ...
Ontario Committee on the Status of Women   +1 more
core  

Prevalence of transthyretin cardiac amyloidosis in undifferentiated heart failure with preserved ejection fraction

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1176-1182, April 2025.
Abstract Aims Transthyretin amyloid cardiomyopathy (ATTR‐CM) is an increasinglyrecognized cause of heart failure with preserved ejection fraction (HFpEF), which may be diagnosed non‐invasively using 99mTc 3,3‐diphosphono‐1,2‐propanodicarboxylic acid (DPD) scintigraphy‐based diagnostic criteria.
L. Healy   +15 more
wiley   +1 more source

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