Results 141 to 150 of about 134,980 (300)

Development and Validation of an RP-HPLC Method for the Simultaneous Quantification of Metformin and Curcumin

open access: yesCyprus Journal of Medical Sciences
BACKGROUND/AIMS: Metformin, a common drug for managing type 2 diabetes, and curcumin, a bioactive compound from turmeric, exhibit complementary therapeutic properties, particularly for metabolic disorders.
Bahareh Noshadi   +2 more
doaj   +1 more source

A Novel Multimodal LC-MS/MS Panel for the Comprehensive Diagnosis of Neurometabolic Disorders in CSF. [PDF]

open access: yesJ Inherit Metab Dis
ABSTRACT Metabolic testing of cerebrospinal fluid (CSF) is essential for early diagnosis of neurometabolic disorders. However, the large number of differential diagnoses, the phenotypic variance within a clinical picture, and the disease rarity complicate targeted metabolic diagnostics.
Christ S   +8 more
europepmc   +2 more sources

Nutritional characterization of Cusco green tea and its synergistic effect with omega‐3 on metabolic and cognitive dysfunctions in obese rats

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Obesity and its metabolic complications, such as insulin resistance and cognitive decline, remain a global health challenge. Green tea (Camelia sinensis) and ω‐3 polyunsaturated fatty acids (PUFAs) are recognized for their antioxidant, anti‐inflammatory, and neuroprotective properties.
Paola Finetti‐Casanova   +5 more
wiley   +1 more source

Performance of 2-Amino Tetraphenyl Porphyrin as Stationary Phase in RP-HPLC of Amino Acids [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2002
The search for new stationary phases has been one of the predominant concerns in high performance liquid chromatography (HPLC) in order to achieve better resolutions, longer column lives, and reduce the time of analysis.
Majid Soleimani   +1 more
doaj  

Insect‐resistant soybean genotypes accumulate rutin and its O‐methylated derivative narcissin, a more potent flavonol targeting Anticarsia gemmatalis digestive and detoxification enzymes and reducing larval survival

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Soybean underpins Brazil's agricultural, yet its sustainability is threatened by lepidopteran pests such as Anticarsia gemmatalis. Although insect‐resistant cultivars have long been associated with the constitutive accumulation of quercetin‐derived flavonols, the biochemical mechanisms underlying this resistance remain poorly ...
Jessica Nunes de Assis   +9 more
wiley   +1 more source

Photooxidation of 18‐Carbon Polyunsaturated Fatty Acids to Prepare Mono‐Hydroxylated Octadecanoids

open access: yesLipids, EarlyView.
We developed a fast and simple one‐step synthetic strategy to produce mono‐hydroxylated metabolites based on the photosensitized oxidation of 18‐carbon polyunsaturated fatty acids (PUFAs). This approach could likely be extended to other PUFAs, suggesting that photosensitized oxidation could be employed to rapidly prepare hydroperoxides from multiple ...
Johanna Revol‐Cavalier   +2 more
wiley   +1 more source

Diacetylene‐Functionalized Glycan Mimetics for Receptor‐Mediated Cluster Imprinting in Model Membranes

open access: yesMacromolecular Rapid Communications, EarlyView.
Diacetylene‐containing glycan mimetics cluster upon selective lectin binding in GUVs. Subsequent irradiation leads to the formation of fluorescent polymer clusters, while non‐clustered glycan mimetics remain unaffected in the membrane. ABSTRACT The glycocalyx, a dense layer of glycoproteins and glycolipids on eukaryotic cells, is essential for cellular
Luca‐Cesare Blawitzki   +5 more
wiley   +1 more source

Advancements in Mass Spectrometry‐Based Glycomics in Food and Nutritional Science

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT This review highlights advancements in mass spectrometry (MS)‐based glycomics in food and nutritional science. Carbohydrates, which are vital for human health, exhibit complex structures, making their analysis challenging. MS has become an indispensable tool for elucidating the structures of carbohydrates, including glycans, through soft ...
JaeHui Song   +3 more
wiley   +1 more source

Development and validation of stability indicating RP-HPLC method for nebivolol by using the DOE approach

open access: yesJournal of Applied Pharmaceutical Research
Background: Nebivolol (NBV), classified as a third-generation β1-adrenergic receptor antagonist, is commonly prescribed for managing hypertension. Accurate and prompt quantification of NBV in bulk materials and pharmaceutical formulations is crucial for ...
Anant Ghongade, Shruti Barot
doaj   +1 more source

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