Results 181 to 190 of about 134,980 (300)

Resolving Isomeric Structures in Natural Complex Carbohydrates: A Comparative Study of SLIM and Cyclic Ion Mobility Platforms

Rapid Communications in Mass Spectrometry, Volume 40, Issue 15, 15 August 2026.
ABSTRACT Rationale Recent advances in ion mobility mass spectrometry (IMS) have led to the development of high‐resolution platforms such as cyclic IMS and SLIM IMS (structures for lossless ion manipulations), both offering enhanced capabilities for resolving complex biomolecular conformations.
Rania Benazza, Christopher P. Harrilal, Yehia M. Ibrahim, Mathieu Fanuel, David Ropartz, Hélène Rogniaux   +5 more
wiley   +1 more source

Characterization of Grape Cane Stilbenoids and Their Photo‐Degradation Products by HPLC‐DAD Coupled With Trapped Ion Mobility Spectrometry and High‐Resolution Tandem Mass Spectrometry

Rapid Communications in Mass Spectrometry, Volume 40, Issue 15, 15 August 2026.
ABSTRACT Rationale Bioactive (E)‐stilbenoids in vine extracts are prone to light‐induced transformation into the respective (Z)‐isomers and further degradation products, often resulting in a loss of bioactivity. We sought to study stilbenoid degradation beyond that of the well‐researched resveratrol due to the high diversity of stilbenoids in nature ...
Paul Besrukow, Friederike A. Schnitker, Ralf Schweiggert, Christof B. Steingass   +3 more
wiley   +1 more source

A sstR2-targeted radiohybrid theranostic agent for PET imaging and β^- therapy with excellent preclinical performance. [PDF]

Npj Imaging
Deiser S, Fenzl S, König V, Inoue S, Casini A.   +4 more
europepmc   +1 more source

Method Development and Validation for the Simultaneous Analysis of Miconazole Nitrate, Hydrocortisone and Chlorocresol in a Pharmaceutical Topical Cream by Reverse Phase Liquid Chromatography

Analytical Science Advances, Volume 7, Issue 1, June 2026.
Development and optimization of a reverse‐brphase chromatography method is done for the simultaneous analysis of hydrocortisone, miconazole nitrate, chlorocresol in a pharmaceutical topical cream. Key parameters are evaluated in this study. The optimum conditions are; volume (10 µL), temperature (30°C), flow rate (1 ml/min), gradient elution program ...
Netai Mukaratirwa‐Muchanyereyi, Pretty Chihiya, Stephen Nyoni   +2 more
wiley   +1 more source

Edulitin 2, a Ribotoxin‐Like Protein From Boletus edulis That Triggers Apoptosis in Colon Cancer Cells While Preserving the Integrity of the Intestinal Microbiota

eFood, Volume 7, Issue 3, June 2026.
Edulitin 2 is a ribotoxin‐like protein exhibiting a potent antiproliferative activity towards Caco‐2 and HT29 cells by programmed cell death. However, edulitin 2 does not affect gut microbiota growth, despite damaging fungal ribosomes. ABSTRACT Porcini (Boletus edulis Bull.) are a reservoir of pharmacological biomolecules with health‐promoting ...
Massimo Bortolotti, Sara Ragucci, Federica Falà, Anella Saggese, Francesco Biscotti, Ylenia De Luca, Nicola Landi, Paolo V. Pedone, Andrea Bolognesi, Ezio Ricca, Letizia Polito, Antimo Di Maro   +11 more
wiley   +1 more source

Determination of Gentamicin C-subtypes in Inner Ear Perilymph Using Liquid Chromatography with Fluorescence Detection. [PDF]

J Pharm Biomed Anal
Dash S, McDevitt MT, Smith DD, Steyger PS.   +3 more
europepmc   +1 more source

Identification and Quantification of Volatile Organic Compounds and Bioaerosols in the Conservation Processes of Guanche Mummies

Archaeometry, Volume 68, Issue 3, Page 561-572, June 2026.
ABSTRACT The Guanche mummies, ancient inhabitants of the Canary Islands, represent a significant part of the historical heritage preserved at the Museum of Nature and Archaeology (MUNA) in Tenerife, Spain. These mummies, subjected to artificial conservation practices, are of great interest to conservators seeking to understand their mummification ...
Benigno Sánchez, Maria Cristina Canela, Maria Garcia Morales, Juan Gilaranz, Murilo de Oliveira Souza, Ruth Mª. Rufino García   +5 more
wiley   +1 more source

Eco-optimized RP-HPLC method for chiral tazobactam and piperacillin drugs: integration with Box-Behnken design and multi-sustainability tools. [PDF]

Sci Rep
Al-Wasidi AS, Sanari JA, Alminderej FM, Saleh SM, Ahmed HA, Mohamed MA.   +5 more
europepmc   +1 more source

Unimolecular GLP‐1/Apelin Hybrid Peptides Cause Prominent Appetite Suppression, as Well as Enhancing Insulin Secretion, Beta‐Cell Survival and Glycaemic Regulation

Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 4706-4717, June 2026.
ABSTRACT Aim To characterise the metabolic benefits of a GLP‐1/apelin hybrid peptide, namely exendin‐4‐linker‐apelin (ELA), and associated acylated forms, including ELA‐Lys12(γGluPal), ELA‐Lys27(γGluPal) and ELA‐Lys38(γGluPal). Methods Concentration‐ and receptor‐dependent effects of the peptides on insulin secretion and beta‐cell turnover were ...
Ananyaa Sridhar, Ethan S. Palmer, Sarah L. Craig, Elzbieta Krason‐Kidzinska, Nigel Irwin, Finbarr P. M. O'Harte   +5 more
wiley   +1 more source

Improvement of Analysis and Transferability in Peptide Purification: From HPLC to FPLC and Back Again. [PDF]

J Pept Sci
Streuli A, Erckes V, Nardone B, Bedard V, Beland F, Steuer C.   +5 more
europepmc   +1 more source