Results 211 to 220 of about 134,980 (300)

Pharmacognostic Specifications and RP-HPLC Analysis of Manilkara hexandra Stembark

open access: yesPharmacognosy Research
Sapna Sharma   +4 more
openaire   +1 more source

Total chemical synthesis of pentameric cholera toxin subunit B.

open access: yesChem Commun (Camb)
Spaltenstein P   +4 more
europepmc   +1 more source

Sample Preparation and Separation of Lignans by Liquid Chromatography

open access: yesJournal of Separation Science, Volume 49, Issue 5, May 2026.
ABSTRACT Lignans are important phytochemicals found mostly in the resins of coniferous trees, but are also introduced into human diets through foods such as sesame seeds and extra‐virgin olive oil. They are pharmacologically interesting mainly because of their antioxidant activities, and they have also been shown to have cytotoxic and antimicrobial ...
Miikka Paloluoto, Susanne K. Wiedmer
wiley   +1 more source

Fusion Molecules Between the STAT5b Inhibitor Stafib‐2‐CR and a Cereblon Ligand

open access: yesChemistryOpen, Volume 15, Issue 5, May 2026.
The design and synthesis of fusion molecules between the selective STAT5b inhibitor Stafib‐2‐CR and a ligand of the E3 ubiquitin ligase cereblon is reported. Activity analysis in fluorescence polarization assays and isothermal titration calorimetry indicated that the chosen attachment point for the linker is well‐suited to retain activity of the fusion
Theresa Münzel   +4 more
wiley   +1 more source

Biophysical characterization of Cyclophilin B reveals membrane localization as its primary functional determinant as a prolyl isomerase

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract The endoplasmic reticulum (ER) provides a specialized environment for the folding of secreted and membrane proteins, a process supported by many different chaperones. Among these chaperones, peptidyl‐prolyl cis/trans isomerases (PPIases) catalyze a rate‐limiting conformational step in protein folding, yet the principles governing isoform ...
Sarah C. DeVoe   +7 more
wiley   +1 more source

Influence of Peptide‐Based Chelator Sequences on HER2‐Targeting Radiopeptide

open access: yesJournal of Peptide Science, Volume 32, Issue 5, May 2026.
Peptide‐based chelator consisting of Cys‐Gly‐Gly‐Gly incorporated into HER2‐targeting rL‐A9 peptide for 99mTc‐labeling. [99mTc]Tc‐CGGG‐rL‐A9 exhibited high binding affinity and tumor uptake and retention. ABSTRACT In our pursuit of developing HER2‐targeting radiolabeled peptides for detection and therapy of HER2‐positive breast cancer, the previously ...
Sonal Gupta   +5 more
wiley   +1 more source

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