Results 121 to 130 of about 59,779 (309)

Revolutionizing Healthcare With Paper‐Based Nucleic Acid Testing

open access: yesExploration, EarlyView.
This work summarizes strategies to enhance paper‐based devices for nucleic acid testing. Key approaches include optimizing paper platforms, improving nucleic acid amplification, and refining labeling/signaling methods. These advancements aim to boost sensitivity, speed, and usability, making paper‐based diagnostics more effective for point‐of‐care ...
Hong Zhang   +8 more
wiley   +1 more source

Establishment of RPA-Cas12a-Based Fluorescence Assay for Rapid Detection of Feline Parvovirus

open access: yesPolish Journal of Microbiology
Feline parvovirus (FPV) is highly infectious for cats and other Felidae and often causes severe damage to young kittens. In this study, we incorporated recombinase polymerase amplification (RPA) and Cas12a-mediated detection and developed an RPA-Cas12a ...
Wang Ting   +6 more
doaj   +1 more source

Impact of Smoking on Treatment Outcomes in Patients With Human Papillomavirus‐Related Oropharyngeal Cancer

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Patients with HPV+ oropharyngeal cancer (OPC) have worse outcomes with longer smoking history (≥ 10 pack‐years). This has been confirmed in trials of primary radiotherapy but not surgery, suggesting differential smoking impact by treatment received. We assessed smoking‐related outcomes at a single institution.
Michelle M. Kwan   +17 more
wiley   +1 more source

Online Blue Prism Training [PDF]

open access: yes
Robotics is the new innovation in business and has profound impact on the several processes. Due to a multitude of advantages, Online Blue Prism training has attained a peak in the market.
Learner, R
core   +1 more source

Strategies and mechanisms of precision genome engineering: From gene editing to genome writing

open access: yesiMetaOmics, EarlyView.
In this review, we examined the progression of genome manipulation from stochastic nuclease‐mediated cutting toward precise editing and programmable genome writing. We discussed tools like multi‐kilobase RNA‐guided integrators and Artificial Intelligence (AI)‐designed effectors and showed how these advances enable researchers to treat genomes as ...
Kerui Huang   +19 more
wiley   +1 more source

Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects

open access: yesInterdisciplinary Medicine, EarlyView.
Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou   +6 more
wiley   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

open access: yesInterdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li   +7 more
wiley   +1 more source

How To Choose A Blue Prism Training Institute? [PDF]

open access: yes
In today's world when businesses are moving at a very fast pace, it has become inevitable for the organisations to think about something new to automate their business processes.
Learner, R
core   +1 more source

Body, Emotions, and Hormones: A Systematic Review of Body Dissatisfaction, Emotion Regulation, and Puberty in Adolescence

open access: yesJournal of Adolescence, EarlyView.
ABSTRACT Objective Body dissatisfaction often arises from a discrepancy between perceived and ideal body images, posing a risk for psychological issues like depression and eating pathologies, particularly during adolescence. Puberty's rapid physical changes may exacerbate the feeling of dissatisfaction, additionally pubertal changes also influence ...
Isabella Muscolino   +3 more
wiley   +1 more source

27‐color flow cytometry for measurable residual disease detection in B‐cell lymphoblastic leukemia

open access: yes
Cytometry Part B: Clinical Cytometry, EarlyView.
Ryan C. Shean   +3 more
wiley   +1 more source

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