Results 1 to 10 of about 1,154,114 (156)
DNA-binding mechanism and evolution of replication protein A [PDF]
Nature Communications, 2023 Replication Protein A (RPA) is a heterotrimeric single stranded DNA-binding protein with essential roles in DNA replication, recombination and repair. Little is known about the structure of RPA in Archaea, the third domain of life.
Clément Madru +13 more
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In Vivo Targeting Replication Protein A for Cancer Therapy [PDF]
Frontiers in Oncology, 2022 Replication protein A (RPA) plays essential roles in DNA replication, repair, recombination, and the DNA damage response (DDR). Retrospective analysis of lung cancer patient data demonstrates high RPA expression as a negative prognostic biomarker for ...
Pamela S. VanderVere-Carozza +11 more
doaj +2 more sources
Dynamic elements of replication protein A at the crossroads of DNA replication, recombination, and repair [PDF]
Critical Reviews in Biochemistry and Molecular Biology, 2020 Colleen C Caldwell, Maria Spies
exaly +2 more sources
Drosophila RecQ4 Is Directly Involved in Both DNA Replication and the Response to UV Damage in S2 Cells. [PDF]
, 2012 The RecQ4 protein shows homology to both the S.cerevisiae DNA replication protein Sld2 and the DNA repair related RecQ helicases. Experimental data also suggest replication and repair functions for RecQ4, but the precise details of its involvement remain
Cotterill, S +6 more
core +8 more sources
Microbiology Spectrum, 2021 Picornaviruses are a diverse and major cause of human disease, and their genomes replicate with intracellular membranes. The functionality of these replication organelles depends on the activities of both viral nonstructural proteins and co-opted host ...
Jia-Ying Lu +6 more
doaj +1 more source
Microbiology Spectrum, 2023 Kaposi’s sarcoma-associated herpesvirus (KSHV) encodes six highly conserved core replication proteins essential for the viral lytic DNA synthesis, including ORF6 (single-stranded DNA-binding protein), ORF9 (DNA polymerase), ORF40/41 (primase-associated ...
Lee-Wen Chen +7 more
doaj +1 more source
Cellular PSMB4 Protein Suppresses Influenza A Virus Replication through Targeting NS1 Protein
Viruses, 2022 The nonstructural protein 1 (NS1) of influenza A virus (IAV) possesses multiple functions, such as the inhibition of the host antiviral immune responses, to facilitate viral infection. To search for cellular proteins interacting with the IAV NS1 protein,
Chee-Hing Yang +5 more
doaj +1 more source
Virus Research, 2022 Coronavirus subverts the host cell cycle to create a favorable cellular environment that enhances viral replication in host cells. Previous studies have revealed that nucleocapsid (N) protein of the coronavirus porcine epidemic diarrhea virus (PEDV ...
Qinghe Zhu +10 more
doaj +1 more source
The Fis protein has a stimulating role in initiation of replication in Escherichia coli in vivo. [PDF]
PLoS ONE, 2013 The Fis protein is a nucleoid associated protein that has previously been reported to act negatively in initiation of replication in Escherichia coli.
Ingvild Flåtten, Kirsten Skarstad
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SUMOylation Is Essential for Dengue Virus Replication and Transmission in the Mosquito Aedes aegypti
Frontiers in Microbiology, 2022 Small ubiquitin-like modifier (SUMO) is a reversible post-translational protein modifier. Protein SUMOylation regulates a wide variety of cellular processes and is important for controlling virus replication.
Shih-Che Weng, Shin-Hong Shiao
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