Results 171 to 180 of about 144,208 (283)

A Single‐Enzyme Activated CRISPR‐Cas12a Nano System via Subtly Balanced dsDNA for Kinetic‐Gated UDG Detection and Spatiotemporal Cellular Imaging

Advanced Science, Volume 13, Issue 28, 18 May 2026.
Kinetic‐gated CRISPR–Cas12a activation enables single‐enzyme detection and spatiotemporal imaging of UDG ABSTRACT Uracil‐DNA glycosylase (UDG) is a key enzyme in base excision repair and an important biomarker for genomic stability and disease. In many reported sensing systems, uracil excision is coupled to signal generation through additional ...
Kejun Dong, Hao Hu, Haiyun Wang, Zijia Zheng, Shuangshuang Cheng, Wan Shu, Ruisi Liu, Xiaoyan Xin, Shiyi Huang, Dingchao Qian, Xianjin Xiao, Qiang Fu, Hongbo Wang   +12 more
wiley   +1 more source

Trends of nucleic acid - based point-of-care diagnostics for infectious diseases. [PDF]

J Biol Eng
Hatem H, Mysara M, Ramadan R.
europepmc   +1 more source

Digital Technologies Disclosure and the Cost of Capital: The Mediating Role of Sustainability Performance

Business Strategy and the Environment, Volume 35, Issue 4, Page 5895-5925, May 2026.
ABSTRACT This study examines the economic consequences of Digital Technologies Disclosure (DTD), focusing on its impact on the cost of capital. The increasing significance of digital transformation in shaping corporate strategies and market perceptions motivates the study.
Hussein Mohsen Saber Ahmed, Awad Elsayed Awad Ibrahim, Khaldoon Albitar   +2 more
wiley   +1 more source

Prognostic Value and Therapeutic Implications of MRI‐Based Negative Lymph Nodes in Nasopharyngeal Carcinoma

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background This study aimed to evaluate the prognostic significance of negative lymph nodes (LNnegs) identified by magnetic resonance imaging (MRI) and treatment implications in patients with N0 locoregionally advanced NPC. Methods This retrospective cohort study included 753 patients with T3–4N0M0 NPC receiving concurrent chemoradiotherapy ...
Ze‐Qi Lin, Chu‐Yu He, Shui‐Qing He, Dong‐Yu Dai, Kai‐Bin Yang, Ji‐Bin Li, Li‐Zhi Liu, Ying Huang, Yuan Zhang, Xu Liu, Jun Ma, Jia‐Ni Liu, Cheng Xu   +12 more
wiley   +1 more source

Surgical repair of isolated right pulmonary artery using pulmonary artery flap and preserved PDA stent. [PDF]

J Cardiothorac Surg
Yoneyama F, Aregullin EO, Brenes J.
europepmc   +1 more source

A Novel PTPN2 Isoform Differentially Regulates Immune Response

European Journal of Immunology, Volume 56, Issue 5, May 2026.
The A allele of the intronic SNP rs80262450 in the PTPN2 gene favors the expression of the splicing isoform PTPN2.4. This cytoplasmic isoform enhances TNF‐α production in myeloid cells, thereby contributing to intestinal inflammation. These findings identify PTPN2.4 as a key pathogenic regulator and potential therapeutic target for inflammatory bowel ...
Xiaoguang Li, Fedik Rahimov, Rui Wang, Lei Gao, Renze Ma, Tiankai Han, Yingtao Bi, Freidrich Cruz, Jing Wang, Shaun Grosskurth, Elizabeth Asque, Jesus Paez‐Cortez, Marc C. Levesque, Nancy E. Crosbie, Timothy Radstake, Amlan Biswas, Kanstantsin Katlinski   +16 more
wiley   +1 more source

Adaptable, quantitative CRISPR/Cas12a-based assay for cytomegalovirus DNA in infant saliva. [PDF]

Sci Rep
Chao K, Dietrich ML, Covey SC, Momoh M, Gutt EG, Sandi JD, Kamara MS, Fofanah IU, Rogers MM, Kallon TMPS, Samuels RJ, Grant DS, Sabeti PC, Garry RF.   +13 more
europepmc   +1 more source

East Goes West: A Record of Eastern Denitrification in the Western Equatorial Pacific

AGU Advances, Volume 7, Issue 3, June 2026.
Patrick A. Rafter
wiley   +1 more source

Evaluation of recombinase polymerase amplification assays for targeted detection of bovine respiratory disease bacterial pathogens and antimicrobial-resistance genes in feedlot calves. [PDF]

J Vet Diagn Invest
Funk T, McLeod L, Zaheer R, Claassen C, Yevtushenko C, Conrad C, Abi Younes J, Lehmann M, Gow S, Wobeser B, Otto SJG, Waldner C, McAllister T.   +12 more
europepmc   +1 more source

Exploring Health Locus of Control and Risk Perception: Connecting Efficacy to Protective Action Through Winter Weather Forecast Messages

Meteorological Applications, Volume 33, Issue 3, May/June 2026.
Through a 2 × 2 between‐subjects experimental design varying winter weather forecasts and health impact information, we investigated the influence of efficacy and health locus of control (HLOC) on risk perception and protective behavioral intention.
Zoey Rosen, Will Livingston
wiley   +1 more source