Results 201 to 210 of about 67,266 (260)

Trophoblast Extracellular Vesicles Rewire Immunity: A Symptom‐Relief Avenue for Recessive Dystrophic Epidermolysis Bullosa

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
First‐trimester trophoblast EVs are enriched in anti‐inflammatory proteins, lipids, and immunoregulatory miRNAs. EVT‐EVs reprogram monocytes toward a pro‐resolving phenotype and restore immune homeostasis in RDEB, supporting their potential as offering a scalable off‐the‐shelf therapy for chronic inflammatory diseases.
Nell Hirt, Enzo Manchon, Ming Wu, Helene Le Buanec, Pauline Bataille, Emmanuelle Bourrat, Jean‐David Bouaziz, Nabila Jabrane‐Ferrat, Reem Al‐Daccak   +8 more
wiley   +1 more source

A Novel Molecular Assay for Point-of-Care Diagnosis of Paracoccidioidomycosis from Clinical Samples Using Recombinase Polymerase Amplification Coupled with a Lateral Flow Assay. [PDF]

J Fungi (Basel)
Mussin J, Corredor Sanguña L, Rojas FD, Comerci D, Giusiano G.   +4 more
europepmc   +1 more source

Brown Adipose Tissue: Molecular Mechanisms of Regulation, Physiological Functions, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
This review systematically covers three core dimensions of brown adipose tissue (BAT): multilayered regulatory mechanisms governing brown adipocyte differentiation and phenotypic identity, physiological functions and signaling pathways in mediating thermogenesis and systemic metabolic crosstalk between BAT and multiple organs, and emerging clinical in ...
Xiaoli Deng, Yuanyuan Shen, Ying Sun, Lu Lu, Chongkui Sun   +4 more
wiley   +1 more source

Targeting the DNA Damage Response in Cancer

MedComm, Volume 7, Issue 10, October 2026.
Targeting the DNA damage response (DDR) reshapes both tumor vulnerability and antitumor immunity. DNA lesions and DDR inhibitors can promote cytosolic nucleic‐acid sensing, antigen presentation, and immune activation, but can also induce adaptive immune escape.
Yihuan Qiao, Boyu Kang, Jian Zhang, Rui Zhang, Jipeng Li   +4 more
wiley   +1 more source

RPA-ssDNA co-phase separation facilitates RAD51 enrichment during homologous recombination. [PDF]

Nucleic Acids Res
Li Y, Zhao Y, Chen Y, Wang T, Bi L, Bao Y, Chen L, Zhang X, Cheng B, Hu M, Jing S, Liu C, Li W, Sun B.   +13 more
europepmc   +1 more source

Outcrop and subsurface characterisation of a mixed tidal and wave‐influenced coastline (Triassic Red Beds, SE Spain)

Sedimentology, Volume 73, Issue 6, Page 2381-2416, October 2026.
ABSTRACT Paralic depositional systems are complex and heterogeneous sedimentary environments, presenting challenges for predicting reservoir architecture and connectivity. Their stratigraphic and facies variability arises from the dynamic interplay between fluvial, tidal and wave processes, and their sensitivity to sea‐level fluctuations, sediment ...
Luis Miguel Yeste, Marc Gil‐Ortiz, Neil David McDougall, Patricia Cabello, César Viseras   +4 more
wiley   +1 more source

Generation of Allogeneic CAR‐T Circumvents Functional Deficits in Patient‐Derived Autologous Product for Glioblastoma

International Journal of Cancer, Volume 159, Issue 6, Page 1521-1534, 15 September 2026.
Clinical trials of chimeric antigen receptor T‐cell (CAR‐T) therapies in glioblastoma have shown limited clinical benefits. Whether this may be explained by the basal quality of CAR‐T products, which are currently generated using patient, autologous T‐cells, has been little explored.
Sabra K. Salim, Muhammad Vaseem Shaikh, Jeffrey Wei, William T. Maich, Alisha Anand, Oliver Y. Tang, Minomi K. Subapanditha, Zahra Alizada, Yujin Suk, Manoj Singh, Kui Zhai, Aapti Khanna, Benjamin Brakel, Vassil Dimitrov, Zoya Tabunshchyk, Katie Chan, Kevin R. Brown, Parvez Vora, Donald M. O'Rourke, Zev A. Binder, Chitra Venugopal, Jason Moffat, Sheila K. Singh   +22 more
wiley   +1 more source

A Rapid Recombinase Polymerase Amplification-CRISPR/Cas12a Assay for Detecting Grapevine Black-Foot Pathogens. [PDF]

J Fungi (Basel)
Liang W, Wang B, Peng J, Huang C, Zhou Y, Li X, Zhang W, Yan J.   +7 more
europepmc   +1 more source

Halogen Surface Terminations in Ti3C2 MXenes for Interface Engineering in Perovskite Solar Cells

Advanced Materials Interfaces, Volume 13, Issue 18, 22 September 2026.
Controlled halogen surface terminations in Ti3C2${\rm Ti}_3{\rm C}_2$ MXenes enable the isolation of structure‐property relationships, revealing how –Cl and –Br terminations influence interlayer spacing, electronic behavior, and work function. When incorporated into IT‐4F‐based interfacial layers, these MXenes modulate interfacial processes and device ...
Morgana Müller de França, Sara Pescetelli, Antonio Agresti, Jhionathan de Lima, Martin Ignacio Broens, Aditya Sharma, Maiara de Jesus Bassi, Cristiano Francisco Woellner, Hanna Pazniak, Aldo di Carlo, Lucimara Stolz Roman   +10 more
wiley   +1 more source