A rapid isothermal RPA-CRISPR/Cas12a assay for detection of <i>Rickettsia rickettsii</i>. [PDF]
Ozubek S, Liu H, Ganta RR.
europepmc +1 more source
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro +11 more
wiley +1 more source
Development of a Reverse Transcription Recombinase Polymerase Amplification CRISPR/Cas12a Assay for Visual and Highly Specific Identification of Zika Virus. [PDF]
Cong X +14 more
europepmc +1 more source
A Phase I/II Study of Ibrutinib Plus Trastuzumab in HER2‐Positive Metastatic Breast Cancer
ABSTRACT Ibrutinib has demonstrated inhibition of ErbB/HER tyrosine kinases in preclinical models. This Phase I/II study investigated the safety, efficacy, and immunomodulatory effects of ibrutinib in combination with trastuzumab in patients with HER2‐positive metastatic breast cancer (MBC) whose disease had progressed on ado‐trastuzumab emtansine ...
Joyce O'Shaughnessy +10 more
wiley +1 more source
UNG-RPA interaction governs the choice between high-fidelity and mutagenic uracil repair. [PDF]
Mu Y +6 more
europepmc +1 more source
HCV‐Specific T‐Cell Recovery After a Year of SVR Following DAA Therapy
ABSTRACT Direct‐acting antiviral (DAA) drugs lead to sustained virologic response (SVR) in almost all treated patients with chronic hepatitis C virus (HCV) infection. Despite this success, the long‐term effects of HCV clearance by DAA therapy on T‐cell‐mediated antiviral immunity remain unclear, particularly concerning the restoration of immune ...
Tetiana Pozniak +9 more
wiley +1 more source
Recent advances in isothermal amplification techniques for detection of animal diseases. [PDF]
Tooryan F +3 more
europepmc +1 more source
Radiobiology studies of gold nanoparticle‐enhanced radiosensitization in proton therapy
Abstract Background Approximately 50%$\%$ of newly diagnosed cancer patients worldwide receive radiotherapy, most commonly with X‐rays. Proton therapy has emerged as a promising alternative, offering complementary advantages over conventional X‐rays due to its highly localized energy deposition at the Bragg peak, thereby reducing radiation exposure to ...
N. Fuster‐Martínez +13 more
wiley +1 more source
Loss of CHTF18-RFC2/5 leads to replicative gaps and sensitivity to PARP inhibitors. [PDF]
Buckley-Benbow L +4 more
europepmc +1 more source
Bridging Borders, Bridging Barriers: Artificial Intelligence for Dental Education
ABSTRACT The rapid convergence of Artificial Intelligence (AI), Information and Communication Technologies (ICT), and Assistive Technologies (AT) is transforming education, especially its accessibility and inclusivity. This commentary resulted from a think‐tank during a colloquium of academics and practitioners from Europe, Africa, and North America ...
Dieter J. Schönwetter +3 more
wiley +1 more source

