Results 51 to 60 of about 67,227 (309)

Coupling Exponential Rolling Circle Amplification to Lateral Flow Devices for Point‐of‐Care Detection of Viral RNA

open access: yesAngewandte Chemie, EarlyView.
A new exponential RCA (E‐RCA) system was developed and coupled to a toehold system for release of a bridging DNA, allowing for lateral flow detection. The E‐RCA method uses a secondary primer (P2) that binds RCA products (RCAP) to generate extended P2 products that can re‐prime a partially self‐complementary circular template, generating a complete ...
Amal Mathai   +3 more
wiley   +2 more sources

RPA

open access: yes, 2023
This work proposes a fast solution algorithm to a fundamental data science problem, namely to identify Boolean rules in disjunctive normal form (DNF) that classify samples based on binary features. The algorithm is an explainable machine learning method: it provides an explicit input-output relationship.
de Vos, Wout, Balvert, Marleen
openaire   +1 more source

Replication Protein A (RPA) Phosphorylation Prevents RPA Association with Replication Centers [PDF]

open access: yesMolecular and Cellular Biology, 2004
Mammalian replication protein A (RPA) undergoes DNA damage-dependent phosphorylation at numerous sites on the N terminus of the RPA2 subunit. To understand the functional significance of RPA phosphorylation, we expressed RPA2 variants in which the phosphorylation sites were converted to aspartate (RPA2(D)) or alanine (RPA2(A)).
Vitaly M, Vassin   +2 more
openaire   +2 more sources

Plutonium in locations of local sources and its involvement in global circulation

open access: yesNuclear Energy and Technology, 2017
This paper seeks to compare the volumetric activities of the 239+240Pu and 238Pu isotopes in the surface layer of the atmosphere in the locations of different local sources of radioactive contamination, to characterize these sources as applied to the ...
V.G. Bulgakov   +5 more
doaj   +1 more source

INTRODUCTION AND EVALUATION PROBLEM OF BPM AND RPA APPROACHES IN MODERN LOGISTIC SYSTEMS

open access: yesScientific Journal of Astana IT University, 2022
Every modern business system tends to reduce production and management costs. There is a reason different management tools are actively introduced into different types of entrepreneurships, from the tiniest shops and online stores to global companies ...
Raissa Uskenbayeva   +2 more
doaj   +1 more source

RPA-2 heterozygous knockout cells present growth and DNA replication impairment and S-phase progression delay.

open access: yes, 2016
A. Growth curve of RPA-2+/- and wild type (wt) cells. * indicates the day during the growth curve that samples were taken to perform assays presented in B and C. B.
Osvaldo Augusto Sant’Anna (3589712)   +10 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Using software based on the Monte-Carlo method for receiving the few-group homogenized macroscopic interaction cross-section

open access: yesTrudy Odesskogo Politehničeskogo Universiteta, 2017
The constant preparation issues are important for performing the few-group analysis for different states of the reactor core. Besides, the constant preparation method influences the further calculations accuracy and quality.
Galchenko V. V. Abdulaev А. М. Shlapak І. І.   +2 more
doaj   +1 more source

Schematic illustration of HLB-RPA-LFA principle for the detectionof ‘Ca. L. asiaticus’.

open access: yes, 2018
(A) Amplification of FAM-biotin-linking ‘Ca. L. asiaticus’ 16S rRNA amplicons. The RPA driven primers (DKG-F/ Biotin labelled-DKG-R) first generate templates for the annealing of the nfo probe.
Ashish J. Warghane (6078674)   +7 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Home - About - Disclaimer - Privacy