Results 91 to 100 of about 98,793 (209)

Reply: To Exercise at High Intensity Heart Rate or Not to Exercise at High Intensity Heart Rate?

open access: yes
Movement Disorders Clinical Practice, EarlyView.
Lennard I. Boon   +2 more
wiley   +1 more source

Cobalt‐Salen Catalysed Hydration of Alkenes With Water: A Complementary Ionic Approach to the Mukaiyama Hydration

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 5, 3 March 2026.
A cobalt‐salen catalysed hydration of olefins with water is reported, resulting in Markovnikov alcohol products. The reaction proceeds rapidly under mild conditions and exhibits excellent functional group tolerance, supporting a wide range of styrenyl and non‐activated alkenes.
David G. Groves   +3 more
wiley   +1 more source

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

open access: yesAdvanced Science, Volume 13, Issue 13, 3 March 2026.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren   +9 more
wiley   +1 more source

Zolpidem restores sleep and decreases amyloid in a mouse model

open access: yesAlzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION Deficits in non–rapid eye movement (NREM) sleep facilitate Alzheimer's disease (AD) progression. Enhancing gamma‐aminobutyric acid‐ergic (GABAergic) signaling can restore sleep. Unbiased computational analysis identified zolpidem as high‐affinity GABA receptor modulator facilitating chloride transport that could slow AD.
Lu Yu   +6 more
wiley   +1 more source

Exploring the Influence of Salinity Intrusion on the Physical and Menstrual Health Problem of Women in Coastal Bangladesh

open access: yesHealth Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background Menstrual health challenges among women in the coastal area of Bangladesh are increasingly impacted by water salinity, posing significant risks to both their physical and mental well‐being. Aims This study examines the effects of water salinity on the menstrual, hormonal, physical, and mental health of women living in coastal ...
Farhana Yasmin   +3 more
wiley   +1 more source

RPC γ sensitivity simulation

open access: yesNuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2000
A method to simulate the Resistive Plate Chambers (RPCs) γ sensitivity has been developed using a Monte Carlo code. The sensitivity has been evaluated as a function of the γ energy in the range 0.1–100 MeV and for different spectra. To evaluate the response of the detector in a Large Hadron Collider (LHC) background environment the γ energy spectrum ...
Altieri, S   +21 more
openaire   +2 more sources

Top–Down Proteomics of Skinned Human Muscle Fibers Reveals Proteoform‐Resolved Fiber‐to‐Fiber Variability

open access: yesJournal of Mass Spectrometry, Volume 61, Issue 3, March 2026.
ABSTRACT Human skeletal muscle is composed of highly heterogeneous single muscle fibers (multinucleated single cells) that are commonly classified as fast or slow fiber types, yet proteoform‐resolved characterization of individual human muscle fibers remains lacking. Herein, we establish a high sensitivity top–down proteomics method for the analysis of
Mallory C. Wilson   +7 more
wiley   +1 more source

Dynamic Reaction and Damage Evaluation of Reactive Powder Concrete Strengthened Reinforced Concrete Columns Subjected to Explosive Load

open access: yesBuildings
China has an existing building area of 80 billion square meters, where reinforced concrete structures have a large quantity and a wide surface area. The risk of structures being subjected to blast loading is relatively high.
Siyuan Qiu   +4 more
doaj   +1 more source

Retinal Capillary Density Reduction Contributes to Dysthyroid Optic Neuropathy via an L‐Arginine‐NO Pathway: A Metabonomics and Clinical Trial Study

open access: yesMedComm, Volume 7, Issue 3, March 2026.
Oxidative stress induces endothelial nitric oxide synthase (eNOS) uncoupling and L‐arginine depletion, reducing nitric oxide (NO) bioavailability in vascular endothelium and contributing to decreased retinal capillary density (RCD) in dysthyroid optic neuropathy (DON).
Yunhai Tu   +12 more
wiley   +1 more source

Single‐Particle Characterization Reveals Heterogeneous Extracellular Vesicle Fusion with Liposomes

open access: yesSmall Methods, Volume 10, Issue 5, 9 March 2026.
This study used five orthogonal single‐particle techniques to compare how common mechanical methods fuse extracellular vesicles with liposomes. By quantifying fused‐particle yield, purity, and vesicle integrity, we found that freeze‐thaw and sonication generated the highest fusion but that all methods introduced membrane perturbation or damage.
Rachel R. Mizenko   +6 more
wiley   +1 more source

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