OmpK36 GD insertion induces RpoS-dependent blaKPC overexpression in carbapenem-resistant Klebsiella pneumoniae [PDF]
Antimicrobial Agents and ChemotherapyGly115-Asp116 (GD) insertion in the outer membrane porin OmpK36 is prevalent in carbapenem-resistant, KPC-producing Klebsiella pneumoniae, but the molecular mechanisms linking this mutation to enhanced resistance cannot be explained simply by reduced ...
Jinnuo Zhu +7 more
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Frontiers in Microbiology, 2019 Maintenance of Borrelia burgdorferi within its enzootic cycle requires a complex regulatory pathway involving the alternative σ factors RpoN and RpoS and two ancillary trans-acting factors, BosR and Rrp2.
Kelly L Hawley +2 more
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Hydrophobicity of Residue 128 of the Stress-Inducible Sigma Factor RpoS Is Critical for Its Activity
Frontiers in Microbiology, 2017 RpoS is a key stress-inducible sigma factor that regulates stress resistance genes in Escherichia coli, such as the katE gene encoding catalase HPII and the glg genes encoding glycogen synthesis proteins.
Takashi Matsuo +2 more
exaly +3 more sources
RpoS impacts global gene expression and carbon source utilization in Escherichia coli O104:H4 [PDF]
Frontiers in MicrobiologyBackgroundEscherichia coli (E. coli) O104:H4 caused the 2011 enterohemorrhagic E. coli (EHEC) outbreak in Germany, which remains the outbreak with the highest incidence of hemolytic uremic syndrome worldwide. We recently identified an E.
Petya Berger +9 more
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بیان ژنrpoS در سویۀ جهش‌یافتۀ اشریشیا کلی با مقاومت زیاد به سیپروفلوکسازین [PDF]
Biological Journal of Microorganism, 2020 چکیده مقدمه: سیپروفلوکسازین، آنتی‌بیوتیکی با طیف اثر وسیع از خانوادۀ فلوروکینولون‌هاست که هدف اصلی آن در اشریشیا کلی، DNAژیراز است. سیپروفلوکسازین سبب القای پاسخ SOS از طریق RecA می‌شود. حضور پروتئین RecF برای فعالیت RecA ضروری است. recF در فاز نمایی به
ملیکا آهنگر +2 more
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Frontiers in Microbiology, 2022 Shewanella baltica is the dominant bacterium that causes spoilage of seafood. RpoS is an alternative sigma factor regulating stress adaptation in many bacteria. However, the detailed regulatory mechanism of RpoS in S. baltica remains unclear.
Caili Zhang +4 more
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Spatial organization of different sigma factor activities and c-di-GMP signalling within the three-dimensional landscape of a bacterial biofilm [PDF]
Open Biology, 2018 Bacterial biofilms are large aggregates of cells embedded in an extracellular matrix of self-produced polymers. In macrocolony biofilms of Escherichia coli, this matrix is generated in the upper biofilm layer only and shows a surprisingly complex ...
Gisela Klauck +3 more
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Residue L193P Mutant of RpoS Affects Its Activity During Biofilm Formation in Salmonella Pullorum
Frontiers in Veterinary Science, 2020 The role of alternative sigma factor RpoS in regulating biofilm formation may differ in various Salmonella Pullorum strains. In this study, the biofilm-forming ability of two Salmonella Pullorum strains S6702 and S11923-3 were compared.
Zheng Feng +23 more
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Global repression of host-associated genes of the Lyme disease spirochete through post-transcriptional modulation of the alternative sigma factor RpoS. [PDF]
PLoS ONE, 2014 Borrelia burgdorferi, the agent of Lyme disease, is a vector-borne pathogen that transits between Ixodes ticks and vertebrate hosts. During the natural infectious cycle, spirochetes must globally adjust their transcriptome to survive in these dissimilar ...
Daniel P Dulebohn +2 more
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Compensatory evolution of gene regulation in response to stress by Escherichia coli lacking RpoS. [PDF]
PLoS Genetics, 2009 The RpoS sigma factor protein of Escherichia coli RNA polymerase is the master transcriptional regulator of physiological responses to a variety of stresses.
Daniel M Stoebel +3 more
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