Results 111 to 120 of about 10,268 (230)

Green Hydrogen as a Sustainability Transition in Spain: Motivations and Implications for Energy Governance

open access: yesSustainable Development, EarlyView.
ABSTRACT Green hydrogen has emerged as a strategic component of Spain's decarbonization agenda, with the country leveraging its renewable energy potential and industrial capabilities to align with the European Union's climate goals. Drawing on a multidimensional theoretical framework, this article examines the key drivers shaping Spain's green hydrogen
Zeynep Arıöz, Xira Ruiz‐Campillo
wiley   +1 more source

Proteinuria as a Risk Factor for Decline in Residual Renal Function in Non-Diabetic Peritoneal Dialysis Patients

open access: yesKidney & Blood Pressure Research, 2013
Background: Preservation of residual renal function (RRF) is a major issue for patients on peritoneal dialysis (PD). Whether proteinuria is associated with a decline in RRF in patients on PD remains unclear.
Seok Hui Kang   +4 more
doaj   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Immune checkpoint inhibitor‐induced arrhythmias: Mechanistic insights from clinical and preclinical studies

open access: yesBritish Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, but their efficacy continues to be limited by immune‐related adverse events. Among these, ICI‐induced cardiac arrhythmias are increasingly recognised as a major adverse reaction, encompassing a broad spectrum of clinical phenotypes, including conduction blocks, atrial fibrillation and
Anand R. Ramalingam   +3 more
wiley   +1 more source

Acute anaphylactic and multiorgan inflammatory effects of Comirnaty in pigs: evidence of spike protein mRNA transfection and paralleling inflammatory cytokine upregulation

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Rare but severe adverse events (AEs) associated with mRNA‐lipid nanoparticle (LNP) COVID‐19 vaccines, such as Comirnaty, include anaphylaxis and inflammatory organ disorders, but their underlying mechanisms are poorly understood. We aimed to develop an animal model to study these phenomena.
László Dézsi   +13 more
wiley   +1 more source

腹膜透析患者残余肾功能的影响因素及保护策略

open access: yesZhongguo shiyan zhenduanxue, 2014
腹膜透析(peritoneal dialysis,PD)是治疗终末期肾病(end stage renal diseases,ESRD)的替代疗法之一。残余肾功能(residual renal function,RRF)是指肾组织受损后尚健存的清除及内分泌功能。有RRF的PD患者其残肾清除率明显高于无RRF患者,多项研究已做了相关报道。保护RRF能够有效的提高透析患者的生活质量。然而 ...
沈立婷, 崔燕, 崔明姬
doaj  

Recurrent reproductive failure and celiac genetic susceptibility, a leading role of gluten

open access: yesFrontiers in Immunology
IntroductionThe prevalence of gluten-related disorders, mainly celiac disease (CD) and non-celiac gluten sensitivity (NCGS), varies between 0.6% and 13% in the general population.
Eduardo de la Fuente-Munoz   +26 more
doaj   +1 more source

Surviving Males With PORCN Variants: Expanding the Clinical, Molecular, and Mechanistic Spectrum

open access: yesClinical Genetics, EarlyView.
Pathogenic PORCN variants are compatible with male survival in both mosaic and non‐mosaic states, expanding the FDH/PONGOS spectrum and improving diagnosis and genetic counseling. ABSTRACT Pathogenic variants in PORCN cause focal dermal hypoplasia (FDH/Goltz syndrome), an X‐linked dominant disorder historically considered lethal in males, with milder ...
Lucía Miranda‐Alcaraz   +23 more
wiley   +1 more source

The Political Legitimacy of Multilevel Crisis Governance: The EU's Recovery and Resilience Facility

open access: yesJCMS: Journal of Common Market Studies, EarlyView.
Abstract European‐wide crises have required extraordinary responses from the EU and its member states that affected its governance and legal framework as well as its legitimacy. The recent COVID‐19 pandemic spread across borders and involved multiple levels of government to mitigate its socio‐economic impact and facilitate a swift recovery.
Marius Guderjan, Mario Kölling
wiley   +1 more source

The Adaptive Stability of the European Union's Long‐Term Budget

open access: yesJCMS: Journal of Common Market Studies, EarlyView.
Abstract This article examines the adaptive stability of the European Union's long‐term budget from the Delors I package of 1988–1992 to the Multiannual Financial Framework of 2014–2020, focusing on the Common Agricultural Policy (CAP) and Cohesion Policy.
David Moloney, Mads Dagnis Jensen
wiley   +1 more source

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