Results 101 to 110 of about 20,117 (295)
Energy efficiency and spectrum efficiency are the most important issues for future mobile systems. Heterogeneous networks (HetNets) with coordinated multiple points (CoMP) are wildly approved as a promising solution to meet increasing demands of mobile ...
Jia Yu +3 more
doaj +1 more source
Enhancing RRM optimization using a priori knowledge for automated troubleshooting
International audienceThe paper presents a methodology that combines statistical learning with constraint optimization by locally optimizing Radio Resource Management (RRM) or system parameters of poorly performing cells in an iterative manner.
Tiwana, Moazzam Islam +2 more
core
The mechanisms of microRNA cargo sorting to extracellular vesicles, important mediators of cell communication, are not fully understood. This study reveals that the microRNA‐production machinery acts as a ‘hub’ for the sorting of microRNAs to extracellular vesicles, a process regulated by dynamic organelle interactions.
Yuzhou Zeng +6 more
wiley +1 more source
Postoperative arteriovenous fistulas exhibit increased RBMS1 in vascular smooth muscle cells (VSMCs). In experimental AVFs, RBMS1 overexpression aggravates, whereas deletion attenuates, neointimal hyperplasia. RBMS1 binds MPZL1 mRNA and promotes exon 5 skipping to generate MPZL1‐Δ5, which interacts with G3BP1 to activate AKT, driving VSMC proliferation,
Zongda Li +14 more
wiley +1 more source
In this study, we present a method that enables voxel-by-voxel comparison of in vivo imaging to immunohistochemistry (IHC) biomarkers. As a proof of concept, we investigated the spatial correlation between dynamic contrast enhanced (DCE-)CT parameters ...
Hilde J.G. Smits +6 more
doaj +1 more source
Isothermal calorimetric titration of eIF3j with eIF3b-RRM.
The upper panel shows raw data of heat effect (in µcal·s−1) of 20-µl injections of 229 µM eIF3b-RRM into 1.5 ml of 10 µm eIF3j performed at 300 s intervals. The lower panel shows the fitted binding isotherms.
Piotr Neumann (361820) +2 more
core +1 more source
The molecular design strategy that integrates both side chain and backbone engineering in diketopyrrolopyrrole‐based conjugated polymers to identify the optimal balance between doping efficiency and microstructural order is demonstrated. Comprehensive spectroscopic, electrochemical, morphological, and structural characterizations reveal that the ...
Taewoong Han +13 more
wiley +1 more source
Abstract This study examines the impact of soil erosion on agricultural land values in the United States (US) Midwest. Based on a novel county‐level panel data set with information on soil erosion levels and agricultural land values covering five census years (1997, 2002, 2007, 2012, and 2017), we separately investigate the direct effect of two types ...
Le Chen +3 more
wiley +1 more source
Ptbp1 Condensates With Phase Separation-Like Features in Cardiomyocyte Nuclei Regulate Splicing of Proliferative Genes in Neonatal Cardiomyocytes. [PDF]
Phase‐separated Ptbp1 droplets form molecular complexes containing multiple proliferation‐associated molecules. Ptbp1 granules containing four RNA recognition motifs (RRMs) domains are present in the nuclei of mouse cardiomyocytes specifically during the proliferative stage.
Sada T +7 more
europepmc +2 more sources
The RRM domain in GW182 proteins contributes to miRNA-mediated gene silencing
Proteins of the GW182 family interact with Argonaute proteins and are required for miRNA-mediated gene silencing. These proteins contain two structural domains, an ubiquitin-associated (UBA) domain and an RNA recognition motif (RRM), embedded in regions ...
Izaurralde, E. +11 more
core +1 more source

