Results 111 to 120 of about 20,117 (295)

Association Between Genetic Ancestry and Multiple Sclerosis Severity

open access: yesAnnals of Neurology, EarlyView.
Objective The objective of this study was to determine whether genetic ancestry is associated with differences in the clinical course of multiple sclerosis (MS). Methods Participants with MS living in the United Kingdom >18 years old were recruited from 2021 to 2025 and genotyped from saliva using a commercial array. Genetic ancestry was inferred using
Benjamin M. Jacobs   +32 more
wiley   +1 more source

Serum Chitotriosidase Links to Activated Glia at Chronic Active Lesion Rims in Multiple Sclerosis Brain

open access: yesAnnals of Neurology, EarlyView.
Objective The objective of this study was to explore the association between 18 kDa translocator protein (TSPO)‐positron emission tomography (PET)–measurable glial activation and serum chitotriosidase (CHIT1) in people with multiple sclerosis (pwMS), and its expression in postmortem MS brain tissue.
Venla Ahola   +14 more
wiley   +1 more source

REUSE OF SOLID WASTE IN A STEEL COMPANY FROM MINAS GERAIS:

open access: yesITEGAM-JETIA, 2020
The objective of this research was to conduct a study on the process of formation of recyclable raw material (RRM) in a company from the steel sector, pointing out the benefits and limitations of its reuse in the manufacturing process of liquid pig iron.
Igor de Oliveira Santos   +3 more
doaj  

Rrm mobility reporting based on beam management measurements [Elektronisk resurs]

open access: yes
A method, system and apparatus are disclosed. At least one embodiment includes a wireless device, WD, configured to communicate with a network node, the WD is configured to, and/or includes a radio interface and/or processing circuitry configured to ...
Sopasakis, Alexandros,   +4 more
core  

From Linkages to Disconnects: The Rapid Response Mechanism (RRM) under the United States-Mexico-Canada Agreement (USMCA)

open access: yesRevue Interventions Économiques
Labor provisions in the USMCA, and more specifically its RRM, offer a good case study for this special issue. As a tool for labor rights enforcement, it also is a strategic instrument to realign production away from low-cost production areas.
Michèle Rioux   +1 more
doaj   +1 more source

Rrm mobility reporting based on beam management measurements

open access: yes
A method, system and apparatus are disclosed. At least one embodiment includes a wireless device, WD, configured to communicate with a network node, the WD is configured to, and/or includes a radio interface and/or processing circuitry configured to ...
Sopasakis, Alexandros   +3 more
core  

Early‐stage health technology assessment of a curative gene therapy for multiple sclerosis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Multiple sclerosis (MS) is associated with significant early morbidity, reduced life expectancy and substantial healthcare and societal costs. The primary objective of this study is to assess the early cost‐effectiveness potential of a novel gene therapy, IMMUTOL, for MS compared with current high‐efficacy treatment sequences.
Attila Imre, Balázs Nagy, Rok Hren
wiley   +1 more source

CLSM micrographs for the apoptosis/necrosis assay in three normal cell lines after 3 h incubation with 800 ng/ml of RRM-MV; or 800 ng/ml of RRM-C.

open access: yes, 2013
Mouse skin fibroblasts in A; mouse macrophages J774 in B; and CHO in C. No significant cytotoxic effects (apoptosis, necrosis and cellular detachment) were detected in all cell cultures treated with RRM-MV or RRM-C as compared with the non-treated cell ...
Elena Pirogova (80011)   +5 more
core   +1 more source

Anticipatory Stress in Medical Students Before Their First Cadaver Experience: A Physiological Component of Cadaver‐Based Anatomy Education

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Cadaver‐based anatomy education represents a unique biological and sensory experience that may elicit significant physiological responses. However, little is known about the anticipatory phase prior to initial exposure, particularly when evaluated using objective biomarkers.
María Resino‐Rocha   +5 more
wiley   +1 more source

Multiscale Modeling of an 8‐Week Combination Regimen of Bemnifosbuvir and Ruzasvir in Patients with Chronic Hepatitis C Virus Infection

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Bemnifosbuvir (BEM) and ruzasvir (RZR) are pan‐genotypic HCV polymerase (NS5B) and NS5A inhibitors, respectively. In a single‐arm study (NCT05904470), 215 treatment‐naïve, adherent participants with chronic HCV (with or without cirrhosis) received BEM 550 mg QD plus RZR 180 mg QD for 8 weeks.
Carolin Zitzmann   +4 more
wiley   +1 more source

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