Results 11 to 20 of about 20,117 (295)
Scientific Reports, 2017 526-residue FUS functions to self-assemble into reversible droplets/hydrogels, which could be further solidified into pathological fibrils. FUS is intrinsically prone to aggregation, composed of N-terminal low-sequence complexity (LC); RNA-recognition ...
Yimei Lu, Liangzhong Lim, Jianxing Song
doaj +2 more sources
Rapid response manufacturing (RRM) [PDF]
, 1997 US industry is fighting to maintain its competitive edge in the global market place. Today markets fluctuate rapidly. Companies, to survive, have to be able to respond with quick-to-market, improved, high quality, cost efficient products. The way products are developed and brought to market can be improved and made more efficient through the proper ...
Cain, W. D., Waddell, W. L.
openaire +4 more sources
Transfer RNA-Derived Small RNA-5'tiRNAGln Drives HNRNPC Phase Separation to Promote Breast Cancer Bone Metastasis by Regulating IGF1R. [PDF]
Adv Sci (Weinh)This study reveals that 5'tiRNA‐Gln interacts with hnRNPC to promote IGF1R liquid‐liquid phase separation, which drives ERK1/2 signaling activation, EMT, and breast cancer bone metastasis. These findings highlight a novel mechanism of breast cancer bone metastasis and potential therapeutic target in metastatic breast cancer.
Wang B +9 more
europepmc +2 more sources
Qualitative analysis of how patients decide that they want risk-reducing mastectomy, and the implications for surgeons in responding to emotionally-motivated patient requests. [PDF]
PLoS ONE, 2017 Contemporary approaches to medical decision-making advise that clinicians should respect patients' decisions. However, patients' decisions are often shaped by heuristics, such as being guided by emotion, rather than by objective risk and benefit.
Stephen L Brown +9 more
doaj +1 more source
Random regret minimization for analyzing driver actions, accounting for preference heterogeneity
Frontiers in Built Environment, 2022 Increasingly more studies have implemented random regret minimization (RRM) as an alternative to random utility maximization (RUM) for modeling travelers’ choice-making behaviors.
Mahdi Rezapour +2 more
doaj +1 more source
The RRM domain of poly(A)-specific ribonuclease has a noncanonical binding site for mRNA cap analog recognition [PDF]
, 2008 The degradation of the poly(A) tail is crucial for posttranscriptional gene regulation and for quality control of mRNA. Poly(A)-specific ribonuclease (PARN) is one of the major mammalian 3’ specific exo-ribonucleases involved in the degradation of the ...
Naohiro Kobayashi +25 more
core +2 more sources
, 2023 RRM cross-spectrum of β-lactamase protein sequences with common RRM characteristic frequency at f1 = 0.0352±0.0041.
Irena Cosic (80010) +4 more
core +1 more source
Frontiers in Plant Science, 2015 Telomerase-reverse transcriptase (TERT) plays an essential catalytic role in maintaining telomeres. However, in animal systems telomerase plays additional non-telomeric functional roles.
Ladislav eDokládal +7 more
doaj +1 more source
Genetic evaluation of growth using random regression models
Indian Journal of Animal Sciences, 2021 The variability in growth traits provides enormous scope for improvement through selection and breeding. However, growth is a longitudinal trait measured repeatedly on the animal and random regression models (RRM) have been found to be suitable for ...
R VENKATARAMANAN
doaj +1 more source
Frontiers in Physiology, 2020 The aim of this study was to investigate the convergent validity of session rating of perceived exertion (s-RPE) with objective measures of internal training load (TL) in professional classical ballet dancers.
Joseph W. Shaw +9 more
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