Results 21 to 30 of about 56,656 (285)

RRM domain of ALS/FTD-causing FUS characteristic of irreversible unfolding spontaneously self-assembles into amyloid fibrils

open access: yesScientific Reports, 2017
526-residue FUS functions to self-assemble into reversible droplets/hydrogels, which could be further solidified into pathological fibrils. FUS is intrinsically prone to aggregation, composed of N-terminal low-sequence complexity (LC); RNA-recognition ...
Yimei Lu, Liangzhong Lim, Jianxing Song
doaj   +1 more source

Design of 1-Bit Digital Reconfigurable Reflective Metasurface for Beam-Scanning

open access: yesApplied Sciences, 2017
A 1-bit digital reconfigurable reflective metasurface (RRM) with 20 × 20 cells is presented, fabricated and measured for beam-scanning performance in this paper.
Shuncheng Tian, Haixia Liu, Long Li
doaj   +1 more source

Structural insights into a regulatory mechanism of FIR RRM1–FUSE interaction

open access: yesOpen Biology, 2023
FUBP-interacting repressor (FIR) is a suppressor of transcription of the proto-oncogene MYC. FIR binds to the far upstream element (FUSE) of the MYC promoter.
Xiaomin Ni   +3 more
doaj   +1 more source

The repeated replacement method: a pure Lagrangian meshfree method for computational fluid dynamics. [PDF]

open access: yesPLoS ONE, 2012
In this paper we describe the repeated replacement method (RRM), a new meshfree method for computational fluid dynamics (CFD). RRM simulates fluid flow by modeling compressible fluids' tendency to evolve towards a state of constant density, velocity, and
Wade A Walker
doaj   +1 more source

Effect of salt loading on baroreflex sensitivity in reduced renal mass hypertension

open access: yesClinical and Experimental Hypertension, 2017
Background: High dietary salt, as well as renal mass reduction, is known to decrease baroreflex sensitivity in rats. However, the effect of high salt intake on baroreflex sensitivity is unknown in reduced renal mass (RRM) hypertension; therefore, the aim
Besim Özaykan   +2 more
doaj   +1 more source

Biological effects of a de novo designed myxoma virus peptide analogue: evaluation of cytotoxicity on tumor cells.

open access: yesPLoS ONE, 2011
BackgroundThe Resonant Recognition Model (RRM) is a physico-mathematical model that interprets protein sequence linear information using digital signal processing methods.
Taghrid S Istivan   +5 more
doaj   +1 more source

Rapid response mechanism in conflict-affected settings of Cameroon: lessons learned from a multisector intervention for internally displaced persons

open access: yesJournal of Global Health Reports, 2023
The Northwest and Southwest regions of Cameroon have experienced armed conflict over the last seven years, characterized by mass displacement and limited access to health care and social amenities. In response, an emergency intervention programme called "
Lundi-Anne Omam, Alain Metuge
doaj   +1 more source

Heavy-Quark Diffusion and Hadronization in Quark-Gluon Plasma [PDF]

open access: yes, 2011
We calculate diffusion and hadronization of heavy quarks in high-energy heavy-ion collisions implementing the notion of a strongly coupled quark-gluon plasma in both micro- and macroscopic components. The diffusion process is simulated using relativistic
D. Griffiths   +9 more
core   +3 more sources

Crystal structure of the RNA recognition motif of yeast translation initiation factor eIF3b reveals differences to human eIF3b. [PDF]

open access: yesPLoS ONE, 2010
BACKGROUND: The multi-subunit eukaryotic initiation factor3 (eIF3) plays a central role in the initiation step of protein synthesis in eukaryotes. One of its large subunits, eIF3b, serves as a scaffold within eIF3 as it interacts with several other ...
Sohail Khoshnevis   +2 more
doaj   +1 more source

Highly tunable repetition-rate multiplication of mode-locked lasers using all-fibre harmonic injection locking

open access: yes, 2018
Higher repetition-rate optical pulse trains have been desired for various applications such as high-bit-rate optical communication, photonic analogue-to-digital conversion, and multi- photon imaging.
Jeon, Chan-Gi   +3 more
core   +2 more sources

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