Results 21 to 30 of about 14,100 (262)

Structural insights into a regulatory mechanism of FIR RRM1–FUSE interaction

open access: yesOpen Biology, 2023
FUBP-interacting repressor (FIR) is a suppressor of transcription of the proto-oncogene MYC. FIR binds to the far upstream element (FUSE) of the MYC promoter.
Xiaomin Ni   +3 more
doaj   +1 more source

Design of 1-Bit Digital Reconfigurable Reflective Metasurface for Beam-Scanning

open access: yesApplied Sciences, 2017
A 1-bit digital reconfigurable reflective metasurface (RRM) with 20 × 20 cells is presented, fabricated and measured for beam-scanning performance in this paper.
Shuncheng Tian, Haixia Liu, Long Li
doaj   +1 more source

Effect of salt loading on baroreflex sensitivity in reduced renal mass hypertension

open access: yesClinical and Experimental Hypertension, 2017
Background: High dietary salt, as well as renal mass reduction, is known to decrease baroreflex sensitivity in rats. However, the effect of high salt intake on baroreflex sensitivity is unknown in reduced renal mass (RRM) hypertension; therefore, the aim
Besim Özaykan   +2 more
doaj   +1 more source

Biological effects of a de novo designed myxoma virus peptide analogue: evaluation of cytotoxicity on tumor cells.

open access: yesPLoS ONE, 2011
BackgroundThe Resonant Recognition Model (RRM) is a physico-mathematical model that interprets protein sequence linear information using digital signal processing methods.
Taghrid S Istivan   +5 more
doaj   +1 more source

From RDM to RRM

open access: yes, 2023
Based on Research Data Management (RDM) and the FAIR data principles, we will focus on the reproducibility of results and in particular measures to make scientific experiments including all their artifacts transparent and available in an appropriate manner along the research data lifecycle.
openaire   +3 more sources

The repeated replacement method: a pure Lagrangian meshfree method for computational fluid dynamics. [PDF]

open access: yesPLoS ONE, 2012
In this paper we describe the repeated replacement method (RRM), a new meshfree method for computational fluid dynamics (CFD). RRM simulates fluid flow by modeling compressible fluids' tendency to evolve towards a state of constant density, velocity, and
Wade A Walker
doaj   +1 more source

Rapid response mechanism in conflict-affected settings of Cameroon: lessons learned from a multisector intervention for internally displaced persons

open access: yesJournal of Global Health Reports, 2023
The Northwest and Southwest regions of Cameroon have experienced armed conflict over the last seven years, characterized by mass displacement and limited access to health care and social amenities. In response, an emergency intervention programme called "
Lundi-Anne Omam, Alain Metuge
doaj   +1 more source

A Lagrangian meshfree method applied to linear and nonlinear elasticity. [PDF]

open access: yesPLoS ONE, 2017
The repeated replacement method (RRM) is a Lagrangian meshfree method which we have previously applied to the Euler equations for compressible fluid flow.
Wade A Walker
doaj   +1 more source

Crystal structure of the RNA recognition motif of yeast translation initiation factor eIF3b reveals differences to human eIF3b. [PDF]

open access: yesPLoS ONE, 2010
BACKGROUND: The multi-subunit eukaryotic initiation factor3 (eIF3) plays a central role in the initiation step of protein synthesis in eukaryotes. One of its large subunits, eIF3b, serves as a scaffold within eIF3 as it interacts with several other ...
Sohail Khoshnevis   +2 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy