Results 21 to 30 of about 56,276 (174)

RRM domain of ALS/FTD-causing FUS characteristic of irreversible unfolding spontaneously self-assembles into amyloid fibrils

open access: yesScientific Reports, 2017
526-residue FUS functions to self-assemble into reversible droplets/hydrogels, which could be further solidified into pathological fibrils. FUS is intrinsically prone to aggregation, composed of N-terminal low-sequence complexity (LC); RNA-recognition ...
Yimei Lu, Liangzhong Lim, Jianxing Song
doaj   +1 more source

Lactation and test day random regression models for genetic evaluation of Murrah buffaloes

open access: yesIndian Journal of Animal Sciences, 2019
In this study the variance components, genetic parameters and breeding values for 305 day or less milk yield were estimated using lactation model and random regression models for the first three lactations in Murrah buffaloes.
MOHD BAQIR   +6 more
doaj   +1 more source

Rapid response mechanism in conflict-affected settings of Cameroon: lessons learned from a multisector intervention for internally displaced persons

open access: yesJournal of Global Health Reports, 2023
The Northwest and Southwest regions of Cameroon have experienced armed conflict over the last seven years, characterized by mass displacement and limited access to health care and social amenities. In response, an emergency intervention programme called "
Lundi-Anne Omam, Alain Metuge
doaj   +1 more source

Structural insights into a regulatory mechanism of FIR RRM1–FUSE interaction

open access: yesOpen Biology, 2023
FUBP-interacting repressor (FIR) is a suppressor of transcription of the proto-oncogene MYC. FIR binds to the far upstream element (FUSE) of the MYC promoter.
Xiaomin Ni   +3 more
doaj   +1 more source

Isolated pseudo-RNA-recognition motifs of SR proteins can regulate splicing using a noncanonical mode of RNA recognition [PDF]

open access: yes, 2013
Serine/arginine (SR) proteins, one of the major families of alternativesplicing regulators in Eukarya, have two types of RNA-recognition motifs (RRMs): a canonical RRM and a pseudo-RRM.
Allain, F. H. T.   +8 more
core   +1 more source

Rapid response manufacturing (RRM) [PDF]

open access: yes, 1997
US industry is fighting to maintain its competitive edge in the global market place. Today markets fluctuate rapidly. Companies, to survive, have to be able to respond with quick-to-market, improved, high quality, cost efficient products. The way products are developed and brought to market can be improved and made more efficient through the proper ...
Cain, W. D., Waddell, W. L.
openaire   +2 more sources

Effect of salt loading on baroreflex sensitivity in reduced renal mass hypertension

open access: yesClinical and Experimental Hypertension, 2017
Background: High dietary salt, as well as renal mass reduction, is known to decrease baroreflex sensitivity in rats. However, the effect of high salt intake on baroreflex sensitivity is unknown in reduced renal mass (RRM) hypertension; therefore, the aim
Besim Özaykan   +2 more
doaj   +1 more source

The repeated replacement method: a pure Lagrangian meshfree method for computational fluid dynamics. [PDF]

open access: yesPLoS ONE, 2012
In this paper we describe the repeated replacement method (RRM), a new meshfree method for computational fluid dynamics (CFD). RRM simulates fluid flow by modeling compressible fluids' tendency to evolve towards a state of constant density, velocity, and
Wade A Walker
doaj   +1 more source

Redshift Space Distortion of the 21cm Background from the Epoch of Reionization I: Methodology Re-examined [PDF]

open access: yes, 2012
The peculiar velocity of the intergalactic gas responsible for the cosmic 21cm background from the epoch of reionization and beyond introduces an anisotropy in the three-dimensional power spectrum of brightness temperature fluctuations.
Adshead   +59 more
core   +3 more sources

Biological effects of a de novo designed myxoma virus peptide analogue: evaluation of cytotoxicity on tumor cells.

open access: yesPLoS ONE, 2011
BackgroundThe Resonant Recognition Model (RRM) is a physico-mathematical model that interprets protein sequence linear information using digital signal processing methods.
Taghrid S Istivan   +5 more
doaj   +1 more source

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