Results 171 to 180 of about 582,607 (300)

Gut microbial signatures and immunotherapy outcomes in NSCLC and melanoma: a systematic review and meta-analysis. [PDF]

BMC Cancer
Essa MEA, Noori H, Butler J, Ahmed AA.
europepmc   +1 more source

Systematic Engineering of Proteases in Saccharopolyspora Spinosa Reveals Synergistic Enhancement of Spinosad Biosynthesis via Substrate Flux Optimization

Advanced Science, EarlyView.
ARTP mutagenesis yielded Saccharopolyspora spinosa mutant D184 with improved extracellular nitrogen utilization. An integrated workflow of protease genetic manipulation, multi‐omics, and rational synergy design pinpointed a pepP‐clpP‐htpX synergistic triangular combination.
Duo Jin, Wangqiong Chen, Danlu Yang, Qing Liu, Baolong Bai, Zirui Dai, Xirong Liu, Zirong Zhu, Jie Rang, Liqiu Xia   +9 more
wiley   +1 more source

Exploring lactic acid bacteria from fresh fruits, vegetables, and edible flowers: from biodiversity valorisation to food applications. [PDF]

World J Microbiol Biotechnol
Presutto E, Capozzi V, de Chiara MLV, Drider D, Spano G, Fragasso M.   +5 more
europepmc   +1 more source

Repeated Disuse Atrophy Imprints a Molecular Memory in Skeletal Muscle: Transcriptional Resilience in Young Adults and Susceptibility in Aged Muscle

Advanced Science, EarlyView.
Repeated disuse imprints a molecular memory in skeletal muscle, conferring transcriptional resilience in young adults but exaggerated susceptibility in aged muscle, driven by epigenetic regulation of aerobic metabolism, mitochondrial and NAD+ pathways.
Daniel C. Turner, Truls Raastad, Max Ullrich, Stian F. Christiansen, Hazel Sutherland, James Boot, Eva Wozniak, Charles Mein, Emilie Dalbram, Jonas T. Treebak, Daniel J. Owens, David C. Hughes, Sue C. Bodine, Jonathan C. Jarvis, Adam P. Sharples   +14 more
wiley   +1 more source

MitoNGS: an online platform to analyze fish metabarcoding data in high resolution. [PDF]

Mol Biol Evol
Zhu T, Sato Y, Fukunaga T, Miya M, Iwasaki W, Yoshizawa S.   +5 more
europepmc   +1 more source

Glucuronolactone Promotes Mucin Sulfation to Alleviate Deoxynivalenol‐Induced Intestinal Injury via Microbiota‐Dependent and ‐Independent AHR Activation

Advanced Science, EarlyView.
Glucuronolactone (GLU) as a natural metabolite of glucose, increases Lactobacillus amylovorus abundance and luminal IAA level to activate AHR signaling. In addition, GLU itself can directly elevate AHR signaling activity independently of microbiota and IAA.
Chenbin Cui, Beibei Zhang, Jiaxi Tang, Jing Hou, Yueqin Qiu, Kaiguo Gao, Li Wang, Zongyong Jiang, Xuefen Yang   +8 more
wiley   +1 more source

A Comparative Analysis of DNA Metabarcoding and Morphological Identification in Diatoms Reveals Similar Patterns of Environmental Response. [PDF]

Ecol Evol
Gonzalez-Saldias F, Gomà J, Garcés-Pastor S, Wangensteen OS, Pèlachs A, Pérez-Haase A.   +5 more
europepmc   +1 more source

Maize Anther Development Involves Translated Open Reading Frames From 3′ Untranslated Regions

Advanced Science, EarlyView.
This study examined the translation activity across ten stages of maize anther development, integrating transcriptome and small‐peptide data. It linked mutations in translated 3' ORFs to anther sterility, exemplified by Zm00001eb417050_3' ORF (known as APV1). In addition, the data indicated that maize anthers could assimilate CO2 through the stomata in
Chunyu Wang, Yuechao Wu, Shunxi Wang, Han Liu, Siqi Jiang, Yingjia Han, Liuji Wu, Tao Zhang, Mei Zhang   +8 more
wiley   +1 more source

To multicellularity and back again: Description of two new coccoid genera (Portococcus gen. nov. and Pseudanabaenococcus gen. nov.) in the basal "filamentous" order Pseudanabaenales, Cyanobacteria. [PDF]

J Phycol
Strunecký O, Kozlíková-Zapomělová E, Jezberová J, Morais J, Lemus MAT, Štenclová L, Johansen JR, Čapková K, Vasconcelos VMO, Mareš J.   +9 more
europepmc   +1 more source

Illuminating Mitochondrial RNA G‐Quadruplexes as Structural Brakes on RNA Granule Assembly and OXPHOS

Advanced Science, EarlyView.
A new fluorescent probe, MitoQUMA, brings mitochondrial RNA G‐quadruplexes (mtRNA G4s) into view in live cells. This tool reveals that excessive mtRNA G4 formation halts mitochondrial RNA granule (MRG) assembly, opposite to the phase‐separation role of cytoplasmic RNA G4s. A chemical genetic screen further identifies a Wnt/β‐catenin–GRSF1–mtRNA G4 axis
Gui‐Xue Tang, Jia‐Tong Yan, Mao‐Lin Li, Cui Zhou, Jian Wang, Shuo‐Bin Chen, Zhi‐Shu Huang, Jia‐Heng Tan   +7 more
wiley   +1 more source