Results 241 to 250 of about 696,870 (312)

Structures of Naked Mole-Rat, Tuco-Tuco, and Guinea Pig Ribosomes–Is rRNA Fragmentation Linked to Translational Fidelity? [PDF]

Cristina Gutierrez‐Vargas, Swastik De, Suvrajit Maji, Zheng Liu, Zhonghe Ke, Martina Nieß, Andrei Seluanov, Vera Gorbunova, Joachim Frank   +8 more
openalex   +1 more source

DR5 Governs Compound Exocytosis in Colonic Goblet Cells via TATA‐Box Binding Protein‐Dependent Bestrophin‐2 Transcriptional Regulation

Advanced Science, EarlyView.
DR5 knockout exhibits a thinner colonic mucus layer, leading to mild dysbiosis, increased susceptibility to Citrobacter rodentium invasion, and exacerbated epithelial injury. Mechanistically, DR5 binds transcription factor TBP, which regulates the expression of gene Best2 via its promoter.
Ying Wang, Xinyun Li, Yong Wang, Chuhe Yang, Xiaopei Gao, Ke Zhu, Yihang Ren, Jingxin Li, Chuanyong Liu, Bing Xue   +9 more
wiley   +1 more source

Pre-rRNAs control mitosis by maintaining chromosomal segregation through protecting SMC2 from AURKA-mediated phosphorylation. [PDF]

Cell Death Dis
Sun S, Su K, Jiang Y, Wang Y, Hu Y, Wang C, Zhao Z, Zhang C, Xing B, Du X.   +9 more
europepmc   +1 more source

In Situ Assembly of Transformable Monopeptide on Activated Neutrophils Attenuates NETs‐Induced Hepatocellular Carcinoma Metastasis by Disrupting NE Nuclear Translocation

Advanced Science, EarlyView.
Activated neutrophils release extracellular traps (NETs) that promote tumor metastasis. FTP‐NPs are develpoed, a peptidic nanomaterial that binds NE on neutrophil membranes, forming NE‐fibril clusters that deactivate NE and prevent NETs formation. This strategy reduces metastasis and enhances the anti‐tumor immune response by targeting NE subcellular ...
Yichi Chen, Yijun Wang, Haitao Shang, Jiayue Qiu, Ruotian Zhang, Yuxiang Xiong, Tong Wang, Fengyi Wang, Anbang Wu, Xin Lin, Bolin Wu, Chen Huang, Wen Cheng, Lu Zhang   +13 more
wiley   +1 more source

NEMESISdb: A full length 16S rRNA gene dataset for the detection of human, fish, and crustacean potentially pathogenic bacteria. [PDF]

Data Brief
Tran SH, Restrepo-Ortiz CX, Vu DQ, Troussellier M, Bettarel Y, Bouvier T, Bui VN, Minh NH, Hoang TD, Nguyen QH, Auguet JC.   +10 more
europepmc   +1 more source

NOX2‐Driven Oxidative Stress Promotes EndMT and Uncouples Angiogenesis–Osteogenesis at the Bone–Implant Interface in Diabetes

Advanced Science, EarlyView.
NOX2‐driven oxidative stress disrupts angiogenesis–osteogenesis coupling at the diabetic bone–implant interface. Pharmacologic inhibition and endothelial‐specific NOX2 knockout restore type‐H endothelium, suppress EndMT, and improve osseointegration.
Zimei Wu, Qiaodan Hou, Yang Liu, Tingting Chen, Kunkun Yang, Luyao Li, Lin Wang   +6 more
wiley   +1 more source

Post mortem laboratory detection of Helicobacter spp. in swine. [PDF]

Vet Res Commun
Krepelková Z, Karaffová V, Bárdová K, Andrašková S, Novotný J.   +4 more
europepmc   +1 more source

Novel Variant and Known Mutation in 23S rRNA Gene of Mycoplasma pneumoniae, Northern Vietnam, 2023

Dinh Dung Nguyen, Nhan Thi Ho, Lynn G. Dover, Anh Hang Mai Vo, Ha Thi Thanh Ly, Phuong Mai Doan, H. T. Nguyen, Nguyen Thi Thao Luu, An Nhat Pham, Huyen Thi Thanh Tran   +9 more
openalex   +1 more source

Kinetic behavior of 30S rRNA intermediate labeled in developing embryonic cells of Xenopus laevis.

, 1987
Koichiro Shiokawa, Yuchang Fu
openalex   +2 more sources

Fe‐S Protein FDX1 Triggers Tumor‐Intrinsic Innate Immunity via Mitochondrial Nucleic Acids Release to Orchestrate Ferroptosis in CCRCC

Advanced Science, EarlyView.
Restoration of the mitochondrial Fe–S protein FDX1 suppresses clear cell renal cell carcinoma by coupling ferroptosis with tumor‐intrinsic innate immune activation. FDX1 induces mitochondrial dysfunction and mtDNA/mt‐dsRNA release, activating cGAS–STING and RIG‐I/MDA5–MAVS signaling to elicit type I interferon responses, thereby promoting antigen ...
Xing Huang, Shaoqing Yu, Wenjie Wei, Wen Tao, Tianwei Cai, Lequan Wen, Jiali Ye, Chi Zhang, Huayi Feng, Senming Cao, Baojun Wang, Xin Ma, Yan Huang, Xu Zhang   +13 more
wiley   +1 more source