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Evolution of rRNA and origin of mitochondria
Nature, 1981The origin of mitochondria has remained a matter of discussion and speculation since Altmann first proposed the endosymbiont hypothesis in 18901. Mitochondria may have arisen by the invasion of aerobic2,3 or anaerobic photosynthetic4 bacteria into ancestral protokaryotic cells, or in a non-symbiotic fashion by compartmentalization of episomal DNA5,6 ...
Heinrich G. Köchel, Hans Küntzel
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Guiding ribose methylation of rRNA
Trends in Biochemical Sciences, 1997Eukaryotic rRNAs contain a complex set of ribose-methylated nucleotides. Why are these nucleotides modified and how are they selected? A large family of small nucleolar RNAs (snoRNAs) with long complementarities to sites of rRNA methylation has been recently found to guide such modifications, opening up a direct approach to the study of their elusive ...
Jean-Pierre Bachellerie +1 more
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Trends in Cell Biology, 2001
The understanding of the functional organization of a compartmentalized organelle such as the nucleus constitutes one of the major challenges in cell biology today. An essential step towards this goal is the study of the spatial dynamics of RNA synthesis and maturation.
Thierry Cheutin +3 more
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The understanding of the functional organization of a compartmentalized organelle such as the nucleus constitutes one of the major challenges in cell biology today. An essential step towards this goal is the study of the spatial dynamics of RNA synthesis and maturation.
Thierry Cheutin +3 more
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Alternating polarity in rRNA genes
Cell Biology International Reports, 1978Spread nucleolar material from A. exigua exhibits an unusual arrangement of rDNA cistrons. The cistrons form head-to-head "diamond-shaped" doublets with a short spacer separating the members of the doublet. Single cistrons are usually terminal and arrange tail-to-tail with the adjacent doublet, suggesting the possibility of a repeating unit with a tail-
G. Richter +5 more
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Thermodynamics of aminoglycoside–rRNA recognition
Biopolymers, 2003Abstract2‐Deoxystreptamine (2‐DOS) aminoglycosides are a family of structurally related broad‐spectrum antibiotics that are used widely in the treatment of infections caused by aerobic Gram‐negative bacilli. Their antibiotic activities are ascribed to their abilities to bind a highly conserved A site in the 16 S rRNA of the 30 S ribosomal subunit and ...
Daniel S. Pilch +3 more
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Molecular Biology Reports, 1996
RNase MRP is a ribonucleoprotein enzyme with a structure similar to RNase P. It is required for normal processing of precursor rRNA, cleaving it in the Internal Transcribed Spacer 1.
Lasse Lindahl, Janice M. Zengel
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RNase MRP is a ribonucleoprotein enzyme with a structure similar to RNase P. It is required for normal processing of precursor rRNA, cleaving it in the Internal Transcribed Spacer 1.
Lasse Lindahl, Janice M. Zengel
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The 5S rRNA and the rRNA intergenic spacer of the two varieties ofCryptococcus neoformans
Medical Mycology, 1995The intergenic spacers (IGS) separating the 23S-like and 16S-like rDNAs of the two varieties of the human pathogenic fungus Cryptococcus neoformans were amplified, cloned and sequenced. The C. neoformans var. neoformans IGS was 2421 nt with 5S rRNA at positions 1228-1345 3' of the 23S-like rRNA. The C. neoformans var.
J.R. Warner +6 more
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Synthesis of rRNA in sea urchin embryos
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1971Abstract The analysis of nucleolar RNA of sea urchin gastrulae after in vivo labeling with 32 P, [ 3 H]uridine or l -[ Me - 3 H]methionine has revealed two peaks of radioactivity due to RNA's heavier than the mature rRNA, one of about 33 S and 2.58 · 10 6 daltons and the other one of 28 S and 1.58 · 10 6 daltons.
Gabriella Sconzo +5 more
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rRNA Biogenesis in Trypanosomes
2011rRNA processing is a complex and essential process that starts in the nucleolus, continues in the nucleoplasm, and is completed in the cytoplasm. The process involves the concerted action of the small nucleolar RNAs that direct cleavage at distinct sites in the intergenic spaces and modify the rRNA by 2′-O-methylation and pseudouridylation. The process
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