Results 11 to 20 of about 831 (147)

Uptake of Risk‐Reducing Salpingo‐Oophorectomy and Gynaecologic Surveillance Among Germline BRCA Pathogenic Variants Carriers [PDF]

Cancer Medicine
Introduction Risk‐reducing salpingo‐oophorectomy (RRSO) is recommended by international guidelines in women with BRCA1/2 germline pathogenic variants (PV) to prevent ovarian cancer.
Alessandra Inzoli, Serena Negri, Cristina Dell'Oro, Clarissa Costa, Liliana Marchetta, Mariaclara Boccadutri, Simona Fumagalli, Gaia Roversi, Elena Maria Sala, Chiara Celi, Valentina Rossi, Robert Fruscio   +11 more
doaj   +3 more sources

The impact of public insurance on RRSO for HBOC in Japan: a nationwide data study. [PDF]

J Hum Genet
Abstract In Japan, risk management based on genetic disposition, such as risk-reducing surgery for hereditary breast and ovarian cancer (HBOC), is covered by public insurance only for some cancer patients. However, non-cancer clients are forced to pay a high co-payment.
Matsumoto M, Den H, Miura S, Harada A, Nomura H, Arai M, Kumamaru H, Nakamura S, Sekine M, Miura K.   +9 more
europepmc   +3 more sources

Impact of graphical display on the intention to undergo risk-reducing salpingo-oophorectomy and mastectomy in individuals positive for BRCA pathogenic variant [PDF]

Scientific Reports
The BRCA1/2 pathogenic variant (PV) increases the risk of breast and ovarian cancer; thus, risk-reducing salpingo-oophorectomy (RRSO) and mastectomy (RRM) are recommended.
Yoon-Jung Choi, Younju Park, Boyoung Park, Heejung Chae, So-Youn Jung, Kum Hei Ryu, Myong Cheol Lim, Soo Jin Park, Yoon Jung Chang, Sun-Young Kong   +9 more
doaj   +2 more sources

Validation of machine learning-based models to predict and explain the risk of ovarian cancer: a multicentric study on BRCA-mutated patients undergoing risk-reducing salpingo-oophorectomy [PDF]

Frontiers in Oncology
ObjectiveBRCA-mutated women are recommended to undergo bilateral risk-reducing salpingo-oophorectomy (RRSO) after childbearing, due to the lack of effective methods that could be able to early detect the occurrence of ovarian cancer.
Vera Loizzi, Vera Loizzi, Maria Colomba Comes, Francesca Arezzo, Adriana Ionelia Apostol, Adriana Ionelia Apostol, Samantha Bove, Annarita Fanizzi, Robert Fruscio, Robert Fruscio, Vanesa Gregorc, Francesco Legge, Rosanna Mancari, Claudia Marchetti, Claudia Marchetti, Serena Negri, Serena Negri, Giorgia Russo, Laura Vertechy, Giovanni Scambia, Giovanni Scambia, Raffaella Massafra, Gennaro Cormio, Gennaro Cormio   +23 more
doaj   +2 more sources

Reassessing CAC Risk Post-RRSO: The Overlooked Role of Hormone Therapy. [PDF]

JACC CardioOncol
Li B, Wang Y, Chen R.
europepmc   +4 more sources

Uptake of Risk-Reducing Surgeries in an International Real-World Cohort of Hispanic Women [PDF]

JCO Global Oncology
PURPOSEWomen with pathogenic variants (PVs) in breast cancer (BC) and ovarian cancer (OC) associated genes are candidates for cancer risk-reducing strategies. Limited information is available regarding risk-reducing surgeries (RRS) among Hispanics.
Yanin Chavarri-Guerra, Ana Ferrigno-Guajardo, Cynthia Villarreal-Garza, Bertha Alejandra Martinez-Cannon, Julio Abugattas-Saba, Annette C. Fontaine, Darling J. Horcasitas, Pamela Mora-Alferez, Gary W. Unzeitig, Sandra Brown, Alejandro Mohar-Betancourt, Bita Nehoray, Azucena Del Toro-Valero, Adrian Daneri-Navarro, Pamela Ganschow, Ian Komenaka, Yenni Rodriguez, Gubidxa Gutierrez Seymour, Leonora Valdez, Kathleen R. Blazer, Shellie Ellis, Jeffrey N. Weitzel   +21 more
doaj   +2 more sources

Effect of risk-reducing salpingo-oophorectomy on the quality of life in Korean BRCA mutation carriers

Asian Journal of Surgery, 2021
Summary: Background: This study aimed to compare the quality of life (QOL), psychosocial status, sexual function, and menopausal symptoms between the risk-reducing salpingo-oophorectomy (RRSO) and non-RRSO groups comprising BRCA mutation carriers and to
Sumin Chae, Eun-Kyu Kim, Ye Rang Jang, Angela Soeun Lee, Seul Ki Kim, Dong Hoon Suh, Kidong Kim, Jae Hong No, Yong-Beom Kim, Sung-Won Kim, Eunyoung Kang   +10 more
doaj   +1 more source

Factors associated with the decision to undergo risk-reducing salpingo-oophorectomy among women at high risk for hereditary breast and ovarian cancer: a systematic review [PDF]

Korean Journal of Women Health Nursing, 2020
Purpose This systematic review aims to identify factors associated with risk-reducing salpingo-oophorectomy (RRSO), including the uptake rate and decision timing, among women at high risk for hereditary breast and ovarian cancer (HBOC).
Sun-young Park, Youlim Kim, Sue Kim
doaj   +1 more source

Role of Routine Peritoneal Biopsies During Risk Reducing Salpingo-Oophorectomy (RRSO) [PDF]

Geburtshilfe und Frauenheilkunde, 2021
Abstract Objective The objective of this retrospective study was to assess the role of routine peritoneal biopsies during risk reducing salpingo-oophorectomy (RRSO). Methods Data of 204 women who underwent RRSO between January 1, 2014 and February 20, 2020 at Charité – Universitätsmedizin Berlin, Campus Mitte were retrospectively ...
Pross, Therese, Karsten, Maria Margarete, Blohmer, Jens-Uwe, Speiser, Dorothee   +3 more
openaire   +2 more sources

Impact of the coverage of risk-reducing salpingo-oophorectomy by the national insurance system for women with BRCA pathogenic variants in Japan

Scientific Reports, 2023
To determine the impact of the coverage of risk-reducing salpingo-oophorectomy (RRSO) and mastectomy (RRM) as well as genetic testing for BRCA pathogenic variants by the national insurance system in Japan. We compared the clinical background of women who
Hidetaka Nomura, Akiko Abe, Atsushi Fusegi, Teruyuki Yoshimitsu, Satoki Misaka, Atsushi Murakami, Tsuyoshi Matsumoto, Shiho Tsumura, Motoko Kanno, Yoichi Aoki, Sachiho Netsu, Makiko Omi, Terumi Tanigawa, Sanshiro Okamoto, Kohei Omatsu, Mayu Yunokawa, Hiroyuki Kanao, Eri Habano, Hiromi Arakawa, Keika Kaneko, Arisa Ueki, Yurie Haruyama, Hitoshi Inari, Takayuki Ueno   +23 more
doaj   +1 more source