Results 21 to 30 of about 831 (147)

Long-Term Morbidity and Health After Early Menopause Due to Oophorectomy in Women at Increased Risk of Ovarian Cancer: Protocol for a Nationwide Cross-Sectional Study With Prospective Follow-Up (HARMOny Study)

JMIR Research Protocols, 2021
BackgroundBRCA1/2 mutation carriers are recommended to undergo risk-reducing salpingo-oophorectomy (RRSO) at 35 to 45 years of age. RRSO substantially decreases ovarian cancer risk, but at the cost of immediate menopause.
Terra, Lara, Hooning, Maartje J, Heemskerk-Gerritsen, Bernadette A M, van Beurden, Marc, Roeters van Lennep, Jeanine E, van Doorn, Helena C, de Hullu, Joanne A, Mom, Constantijne, van Dorst, Eleonora B L, Mourits, Marian J E, Slangen, Brigitte F M, Gaarenstroom, Katja N, Zillikens, M Carola, Leiner, Tim, van der Kolk, Lizet, Collee, Margriet, Wevers, Marijke, Ausems, Margreet G E M, van Engelen, Klaartje, Berger, Lieke PV, van Asperen, Christi J, Gomez-Garcia, Encarna B, van de Beek, Irma, Rookus, Matti A, Hauptmann, Michael, Bleiker, Eveline M, Schagen, Sanne B, Aaronson, Neil K, Maas, Angela H E M, van Leeuwen, Flora E   +29 more
doaj   +1 more source

Elevated Bone Turnover Markers after Risk-Reducing Salpingo-Oophorectomy in Women at Increased Risk for Breast and Ovarian Cancer. [PDF]

PLoS ONE, 2017
Risk-reducing salpingo-oophorectomy (RRSO) reduces ovarian cancer risk in BRCA1/2 mutation carriers. Premenopausal RRSO is hypothesized to increase fracture risk more than natural menopause.
Ingrid E Fakkert, Eveline van der Veer, Elske Marije Abma, Joop D Lefrandt, Bruce H R Wolffenbuttel, Jan C Oosterwijk, Riemer H J A Slart, Iris G Westrik, Geertruida H de Bock, Marian J E Mourits   +9 more
doaj   +1 more source

Salpingectomy With Delayed Oophorectomy Versus Salpingo-Oophorectomy in BRCA1/2 Carriers: Three-Year Outcomes of a Prospective Preference Trial. [PDF]

BJOG
ABSTRACT Objective To compare menopause‐related quality of life (QoL) after risk‐reducing salpingectomy (RRS) versus risk‐reducing salpingo‐oophorectomy (RRSO) until 3 years of post‐surgery. Design A prospective study (TUBA study) with treatment allocation based on patients' preference.
Van Bommel MHD, Steenbeek MP, Inthout J, Van Garderen T, Harmsen MG, Arts-De Jong M, Maas AHEM, Prins JB, Bulten J, Van Doorn HC, Mourits MJE, Tros R, Zweemer RP, Gaarenstroom KN, Slangen BFM, Brood-Van Zanten MMA, Vos MC, Piek JMJ, van Lonkhuijzen LRCW, Apperloo MJA, Coppus SFPJ, Hoogerbrugge N, Hermens RPMG, De Hullu JA.   +23 more
europepmc   +2 more sources

Risk-reducing salpingo-oophorectomy, natural menopause, and breast cancer risk: an international prospective cohort of BRCA1 and BRCA2 mutation carriers

Breast Cancer Research, 2020
Background The effect of risk-reducing salpingo-oophorectomy (RRSO) on breast cancer risk for BRCA1 and BRCA2 mutation carriers is uncertain. Retrospective analyses have suggested a protective effect but may be substantially biased.
Nasim Mavaddat, Antonis C. Antoniou, Thea M. Mooij, Maartje J. Hooning, Bernadette A. Heemskerk-Gerritsen, GENEPSO, Catherine Noguès, Marion Gauthier-Villars, Olivier Caron, Paul Gesta, Pascal Pujol, Alain Lortholary, EMBRACE, Daniel Barrowdale, Debra Frost, D. Gareth Evans, Louise Izatt, Julian Adlard, Ros Eeles, Carole Brewer, Marc Tischkowitz, Alex Henderson, Jackie Cook, Diana Eccles, HEBON, Klaartje van Engelen, Marian J. E. Mourits, Margreet G. E. M. Ausems, Linetta B. Koppert, John L. Hopper, Esther M. John, Wendy K. Chung, Irene L. Andrulis, Mary B. Daly, Saundra S. Buys, kConFab Investigators, Javier Benitez, Trinidad Caldes, Anna Jakubowska, Jacques Simard, Christian F. Singer, Yen Tan, Edith Olah, Marie Navratilova, Lenka Foretova, Anne-Marie Gerdes, Marie-José Roos-Blom, Flora E. Van Leeuwen, Brita Arver, Håkan Olsson, Rita K. Schmutzler, Christoph Engel, Karin Kast, Kelly-Anne Phillips, Mary Beth Terry, Roger L. Milne, David E. Goldgar, Matti A. Rookus, Nadine Andrieu, Douglas F. Easton, on behalf of IBCCS, kConFab, BCFR   +62 more
doaj   +1 more source

Impact of lower co-payments on risk-reducing salpingo-oophorectomy and BRCA testing in Japan

Archives of Public Health, 2023
Background In April 2020, insurance coverage for risk-reducing salpingo-oophorectomy (RRSO) for breast cancer patients with hereditary breast and ovarian cancer (HBOC) syndrome and BRCA testing were started in Japan.
Katsuyuki Konnai, Hiroyuki Fujiwara, Masakazu Kitagawa, Reina Wakabayashi, Asuna Yumori, Tsuguto Notomi, Ryo Onose, Hisamori Kato, Hiroto Narimatsu   +8 more
doaj   +1 more source

Risk reduction strategies for BRCA1/2 hereditary ovarian cancer syndromes: a clinical practice guideline

Hereditary Cancer in Clinical Practice, 2021
Objective The purpose of this guideline is to make recommendations regarding the care of women who harbour a pathogenic or likely pathogenic variant in BRCA1 and BRCA2.
Michelle Jacobson, Nadia Coakley, Marcus Bernardini, Kelly-Ann Branco, Laurie Elit, Sarah Ferguson, Raymond Kim   +6 more
doaj   +1 more source

Germline , variants in a patient with breast and ovarian cancer at risk for familial cancer syndrome: Is there a role for risk-reducing salpingo-oophorectomy? [PDF]

Obstetrics & Gynecology Science, 2020
A 50-year-old non-Hispanic white Caucasian female was diagnosed with breast cancer and was subsequently found to possess the tumorigenic ataxia telangiectasia mutated (ATM) and PALB2 variants but not the BRCA1 and BRCA2 variants.
Semiramis L. Carbajal-Mamani, Merry J. Markham, Joaquín Santolaya-Forgas, Jacqueline C. Castagno, Joel Cardenas-Goicoechea   +4 more
doaj   +1 more source

Czy RRSO prawidłowo pokazuje rzeczywisty koszt kredytu ponoszony przez dłużnika?

Studia i Prace Kolegium Zarządzania i Finansów, 2023
Rzeczywista Roczna Stopa Oprocentowania (RRSO) jest najbardziej popularnym we wszystkich państwach UE i jednocześnie najważniejszym miernikiem określającym całkowity koszt długu, który ma ułatwić wybór najlepszego (najtańszego) produktu kredytowego.
Piotr Prewysz-Kwinto, Magdalena Redo
openaire   +1 more source

Risk-reducing Salpingo-oophorectomy consults and practices during the COVID-19 pandemic

Gynecologic Oncology Reports, 2022
Objective: Investigate the impact of the COVID-19 pandemic on risk-reducing salpingo-oophorectomies (RRSO) consults. Methods: Survey sent out to 1,127 full members of the Society of Gynecologic Oncology in August 2021.
A.E. O'Mara, C. Benedict, A.W. Kurian, S.K. Wagner, E. Diver   +4 more
doaj   +1 more source

Risk Assessment and Fertility Counseling for Hereditary Gynecological Cancer Syndromes. [PDF]

Cancer Med
ABSTRACT Objective To review the genetic basis, clinical characteristics, and management strategies of hereditary gynecologic cancers associated with hereditary cancer syndromes. Methods Literature on germline mutations, inheritance patterns, clinical manifestations, and fertility preservation strategies was reviewed.
Zhao M, Teng XM, Yan Q, Hao F.
europepmc   +2 more sources