Results 181 to 190 of about 76,658 (267)

Initial Distance‐Dependent Mean Force Drives Synaptic Vesicle Motion Toward Fusion Sites in Stimulated Hippocampal Neurons

Advanced Science, EarlyView.
Synaptic vesicle (SV) motion and exocytosis dynamics in the presynaptic terminals of live neurons are intimately linked to synaptic transmission during neuronal activity. In this work, it is revealed that, during electrical stimulation, SVs located farther from their fusion sites exhibit greater straightness and experience larger mean forces directed ...
Gyunam Park, Ji‐Hyun Kim, Hunki Lee, Chungwon Park, Sidong Chen, Luke Bates, Jaeyoung Sung, Hyokeun Park   +7 more
wiley   +1 more source

Physics-informed transformers for electronic quantum states. [PDF]

Nat Commun
Sobral JA, Perle M, Scheurer MS.
europepmc   +1 more source

AI‐Optimized Vanadium Oxide Multilayers for More Than 20‐fold Enhancement in Bolometric Performance

Advanced Science, EarlyView.
Machine‐learning‐optimized WxV1‐xOy multilayer thin films with graded doping achieve a high TCR (7.3 % K−1), reduced hysteresis, and low noise under CMOS‐compatible growth conditions. This approach overcomes the long‐standing trade‐off in microbolometers between linear response and performance, offering a universal bolometric parameter greatly enhanced
Jin‐Hyun Choi, Hyoung‐Taek Lee, Jeonghoon Kim, Miju Park, Seungjoon Sun, Gye‐Hyeon Kim, Myung‐Ho Kwon, Hyeong‐Ryeol Park, Changhee Sohn   +8 more
wiley   +1 more source

Unraveling the mesoscale resting-state functional connectivity of ocular dominance columns in humans using high-resolution functional MRI. [PDF]

Commun Biol
Schmidt ME, Aganj I, Stockmann J, Bilgic B, Chang Y, Hoge WS, Kirilina E, Weiskopf N, Nasr S.   +8 more
europepmc   +1 more source

HiST: Histological Images Reconstruct Tumor Spatial Transcriptomics via MultiScale Fusion Deep Learning

Advanced Science, EarlyView.
HiST, a multiscale deep learning framework, reconstructs spatially resolved gene expression profiles directly from histological images. It accurately identifies tumor regions, captures intratumoral heterogeneity, and predicts patient prognosis and immunotherapy response.
Wei Li, Dong Zhang, Eryu Peng, Shijun Shen, Hamid Alinejad‐Rokny, Yao Liu, Junke Zheng, Cizhong Jiang, Youqiong Ye   +8 more
wiley   +1 more source

MIDAS: rapid, multiplexed molecular profiling for integrated host-pathogen analysis. [PDF]

Nat Commun
Lim YJ, Asadi Tokmedash M, Allen M, Gruich C, Choi JH, Kim C, Falkowski N, Goldsmith B, Stringer KA, Dickson RP, Bong KW, Min J.   +11 more
europepmc   +1 more source

Real‐Time In Vivo Monitoring of Anastomotic Intestinal Ischemia Using Implantable Resorbable Organic Sensors

Advanced Science, EarlyView.
Resorbable impedance sensors are successfully implanted into porcine small intestinal anastomoses. Impedance was recorded for 2 hours prior, and 2 hours following ischemia induction, and a significant drop in tissue impedance was observed. Abstract Anastomotic failure remains one of the most severe complications in gastrointestinal surgery.
Dennis Wahl, Finn Jaekel, Julia Henne, Richard Kantelberg, Daniel C. Freund, Eberhard Grambow, Brigitte Vollmar, Amelie R. Zitzmann, Hans Kleemann, Jochen Hampe, Sebastian Hinz, Clemens Schafmayer, Karl Leo   +12 more
wiley   +1 more source

Highly Secure In Vivo DNA Data Storage Driven by Genomic Dynamics

Advanced Science, EarlyView.
Integrated computational‐biological programming enables secure in vivo data storage by generating code tables from either genomes or gene regulatory networks, expanding the encryption key space by over 100 orders of magnitude. Storing code tables within synthetic genes, genomes, or gene regulatory networks adds an additional layer of security by ...
Jiaxin Xu, Yu Wang, Haibo Zhou, Mingen Li, Yang Wang, Lingwei Wang, Hui Mei, Junbiao Dai, Shanze Chen, Xiaoluo Huang   +9 more
wiley   +1 more source

Flexible Self-Powered Respiration Sensor Inspired by Fish Lateral Line Systems. [PDF]

Research (Wash D C)
Ma G, Zhang M, Shi G, Gu C, Shen H, Ba K, Zhang Y, Wang D, Liu X, Yu B, Han Z, Ren L.   +11 more
europepmc   +1 more source

SUPER: Upcycling Genetic Parts for Precise Gene Expression Control, Leakage Minimization, and Genetic Circuit Stability

Advanced Science, EarlyView.
To precisely modulate natural and synthetic regulatory parts, SUPER is introduced as a sophisticated and tunable controller of genetic devices without requiring sequence modification on the target. SUPER enhances dynamic range of RNA‐, chemical‐, temperature‐, and protein‐responsive biosensors up to 1011%, and converts biosensors to cover an expanded ...
Taeyang Heo, Dongwon Park, Woosub Shin, Jongmin Kim   +3 more
wiley   +1 more source