Results 21 to 30 of about 612,628 (246)

AS DOENÇAS CRÔNICAS E O DESEJO DE MORTE

open access: yesHematology, Transfusion and Cell Therapy, 2023
A OMS define como doenças crônicas as patologias crônicas de lento desenvolvimento e uma longa duração, podendo acompanhar a pessoa durante toda a vida, requerendo tratamentos duradouros e complexos.
RS Mendes
doaj   +1 more source

DIGITAL MAPPING OF SOIL SALINITY IN KAMPE-OMI IRRIGATION SCHEME

open access: yesAfrican Journal on Land Policy and Geospatial Sciences, 2022
Soil salinity being a problem of irrigated agriculture reduces the productivity of agricultural land adversely. Detection of soil salinity by conventional means of soil survey requires a great deal of time, but remote sensing data and GIS techniques ...
Olumuyiwa Idowu Ojo
doaj   +1 more source

Association between VDR Gene Polymorphisms (rs 1544410, rs 7975232, rs 2228570, rs 731236 and rs 11568820) and Susceptibility to Breast Cancer in a Sample of Southeastern Iranian Population

open access: yesInternational Journal of Cancer Management, 2017
Background: Vitamin D receptor (VDR) is a key nuclear receptor that is associated with the risk and progression of breast cancer (BC). Objectives: The present study investigated the Fok1, Bsm1, Taq1 and Cdx2 polymorphisms in the VDR gene and susceptibility to BC in a sample of Southeastern Iranian population.
Seyed Mehdi Hashemi   +5 more
openaire   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Evaluation of Land Use Changes before and after Iraq and Iran's War (Case Study: Ilam Watershed) [PDF]

open access: yesجغرافیا و پایداری محیط, 2013
Having suitable information about land use changes is very important in planning and management of lands. Therefore, among the various methods to study these changes, satellite images, RS and GIS technologies were selected to detect these changes.
Norodin Rostami   +2 more
doaj  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

ADOECER: UMA DURA REALIDADE

open access: yesHematology, Transfusion and Cell Therapy, 2023
Para a compreensão do processo saúde-doença torna-se relevante o entendimento do conceito de saúde. A OMS conceitua saúde como sendo um estado de completo bem-estar físico, mental e social.
RS Mendes
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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