Results 131 to 140 of about 193,591 (315)

Assessment of the radiological situation near a mothballed uranium mining facility in North-East Kazakhstan

open access: yesScientific Reports
In this study, we present radiometric measurements near the mothballed Grachevskoye uranium mining facility (MUMF) and the settlement of Saumalkol, located in northeast Kazakhstan.
Sergey Subbotin   +7 more
doaj   +1 more source

Population Pharmacokinetics and Transfer of Gabapentin When Used as a Pain Adjunct for Cesarean Deliveries

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 551-560, March 2025.
ABSTRACT Enhanced Recovery After Surgery (ERAS) protocols for cesarean deliveries (CDs) utilize multimodal pain management strategies that often include gabapentin. While gabapentin is excreted in breast milk, its pharmacokinetics in immediately postpartum lactating women are not known. This observational pharmacokinetic study (NCT05099484) enrolled 21
Rebecca Silvola   +9 more
wiley   +1 more source

Disease–Drug–Drug Interaction of Imatinib in COVID‐19 ARDS: A Pooled Population Pharmacokinetic Analysis

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 583-595, March 2025.
ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said   +10 more
wiley   +1 more source

A new Wind Atlas to support the expansion of the Italian wind power fleet

open access: yesWind Energy
As a contribution to national strategic energy planning, recent developments in meteorological modeling and wind generation technologies have improved the representation of the spatio‐temporal features of wind.
Simone Sperati   +11 more
doaj   +1 more source

Tritium content in vegetation cover at nuclear test locations at the “Sary-Uzen” site in the Semipalatinsk Test Site

open access: yesEcotoxicology and Environmental Safety
Numerous areas of the Semipalatinsk Test Site (STS) were subjected to radioactive contamination, including tritium. The tritium content in plants was determined in free water (TFWT) and in the organic component (OBT). It has been established that the OBT
N.V. Larionova   +9 more
doaj   +1 more source

Analysis of C4 Concentrations to Predict Impact of Patient‐Reported Diarrhea Associated With the Ileal Bile Acid Transporter Inhibitor Linerixibat

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 596-605, March 2025.
ABSTRACT Linerixibat, an ileal bile acid transporter (IBAT) inhibitor, is being evaluated for the treatment of pruritus in primary biliary cholangitis (PBC). Diarrhea is commonly reported with this drug class as IBAT inhibition redirects bile acids (BA) to the colon.
Fernando Carreño   +4 more
wiley   +1 more source

Modeling of Disease Progression of Type 2 Diabetes Using Real‐World Data: Quantifying Competing Risks of Morbidity and Mortality

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 606-615, March 2025.
ABSTRACT Type 2 diabetes (T2D) is a progressive metabolic disorder that could be an underlying cause of long‐term complications that increase mortality. The assessment of the probability of such events could be essential for mortality risk management. This work aimed to establish a framework for risk predictions of macrovascular complications (MVC) and
Hanna Kunina   +2 more
wiley   +1 more source

Strategic Spatial Segregation in Silicon Photoelectrodes: Decoupling Catalytic and Optical Functions for High‐Efficiency Solar Water Splitting

open access: yesSmall Structures, Volume 6, Issue 5, May 2025.
A novel spatial segregation strategy for silicon photoelectrodes is demonstrated, where catalyst wires surrounded by tapered microwires effectively decouple competing optical and catalytic requirements. This architectural innovation enables optimal light absorption and catalytic activity while maintaining efficient charge transport, achieving 96.5 ...
Soohyeok Park   +9 more
wiley   +1 more source

Comparative evaluation of noninvasive DNA sampling and line transect surveys for spring density estimation of black grouse and capercaillie

open access: yesWildlife Biology, EarlyView.
Reliable abundance estimates provide essential information in ecology, conservation and management of many wild grouse populations. In this 3‐year study, we comparatively evaluate the suitability of traditional line transect distance sampling of flushed birds versus a spatial capture–recapture survey with noninvasive DNA samples for individual ...
Henrik Brøseth   +2 more
wiley   +1 more source

Leaf photoprotection and water relations traits reveal novel axes of coordination and trade‐offs in leaf function

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Plants can express considerable plasticity in leaf functional traits, but that plasticity may be constrained by coordination and trade‐offs among multiple functions.
Bailey H. McNichol   +3 more
wiley   +1 more source

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