Results 41 to 50 of about 37,268 (291)

Population pharmacokinetics and pharmacodynamics of canagliflozin in paediatric patients with type 2 diabetes mellitus

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Canagliflozin was recently approved in type 2 diabetes mellitus (T2DM) patients ≥10 and <18 years old as a single agent dosed once daily (QD) or in a fixed‐dose combination with metformin dosed twice daily (BID). We characterize canagliflozin pharmacokinetics in paediatric patients with T2DM, compare estimated individual and simulated ...
Nele Goeyvaerts, Per Olsson Gisleskog, Martine Neyens, Juan José Perez Ruixo, Saberi Rana Ali, Iolanda Cirillo, Oliver Ackaert   +6 more
wiley   +1 more source

sj-docx-5-rse-10.1177_07419325221143965 – Supplemental material for Culturally Adapted Social, Emotional, and Behavioral Support for Black Male Learners

, 2023
Supplemental material, sj-docx-5-rse-10.1177_07419325221143965 for Culturally Adapted Social, Emotional, and Behavioral Support for Black Male Learners by Aaron Rachelle Campbell, Mary Rose Sallese, Julie L. Thompson, Constance J.
Julie L. Thompson (2982369), Constance J. Fournier (14420866), Aaron Rachelle Campbell (14136439), Mary Rose Sallese (10913426), Meghan Allen (10704325)   +4 more
core   +1 more source

Relationship between continuous infusion meropenem PK/PD target attainment and C‐reactive protein dynamics in onco‐haematologic patients with febrile neutropenia

British Journal of Clinical Pharmacology, EarlyView.
Aim Meropenem is a second‐line antimicrobial agent in the treatment of febrile neutropenia in onco‐haematological patients. A population pharmacokinetic/pharmacodynamic (PK/PD) analysis for assessing the relationship between meropenem exposure and C‐reactive protein (C‐RP) over time was conducted.
Chun Liu, Pier Giorgio Cojutti, J. G. Coen van Hasselt, Michele Bartoletti, Maddalena Giannella, Pierluigi Zinzani, Pierluigi Viale, Federico Pea   +7 more
wiley   +1 more source

MERIDA HRES: A new high‐resolution reanalysis dataset for Italy

Meteorological Applications
Power utilities are increasingly emphasizing the need for high‐resolution reanalysis datasets to develop resilience plans for protecting and managing infrastructure against extreme weather events.
Francesca Viterbo, Simone Sperati, Bruno Vitali, Filippo D'Amico, Francesco Cavalleri, Riccardo Bonanno, Matteo Lacavalla   +6 more
doaj   +1 more source

Nordic-RSE: Developing an international RSE community

, 2021
This presentation was produced for the CodeRefinery project that was supported by the Nordic e-Infrastructure Collaboration (NeIC), which is part of NordForsk.
openaire   +1 more source

Extrapolation and pharmacokinetic protocol design optimization for ceftriaxone as an exemplar for the development of antibiotics for children

British Journal of Clinical Pharmacology, EarlyView.
Aim Ceftriaxone is a cephalosporin commonly used for the treatment of acute, severe infections; however, there are conflicting data on its disposition properties in children, making it a suitable case study for the evaluation of the appropriateness of extrapolation approaches based on exposure matching principles for paediatric patients and exploring ...
Daniel Valente Neves, Umberto Villani, Salvatore D'Agate, Sean Oosterholt, Ricardo de Carvalho Cavalli, Fabio Carmona, Vera Lucia Lanchote, Oscar Della Pasqua   +7 more
wiley   +1 more source

Critical Review and Analytical Energetic Assessment of Key-parameters for Industry 4.0 Development in Italy through a Cross-comparison with the EU Digitalization Scenarios

Journal of Sustainable Development of Energy, Water and Environment Systems
The term Industry 4.0 has been coined in Germany in 2011 and since then, it has officially started the so-called fourth industrial revolution. In the herein presented review, the industrial digitalization process of Italy is explored and cross-compared ...
Giulia Bellini, Francesca Bazzocchi, Marco Borgarello, Simone Maggiore, Stefano Moscarelli   +4 more
doaj   +1 more source

Entrepreneuriat responsable : relecture du comportement entrepreneurial au prisme de la culture et la spiritualité

Revue Marocaine de l'Entrepreneuriat, de l'Innovation et du Management, 2019
La compréhension des spécificités des processus entrepreneuriaux passe inéluctablement par le recours à une variété de registres sociaux et culturels, y compris spirituels.
Anas HATTABOU, Abderrahman AHMIMID, Soufiane CHRAIBI   +2 more
doaj   +1 more source

sj-docx-1-rse-10.1177_07419325221143965 – Supplemental material for Culturally Adapted Social, Emotional, and Behavioral Support for Black Male Learners

, 2023
Supplemental material, sj-docx-1-rse-10.1177_07419325221143965 for Culturally Adapted Social, Emotional, and Behavioral Support for Black Male Learners by Aaron Rachelle Campbell, Mary Rose Sallese, Julie L. Thompson, Constance J.
Julie L. Thompson (2982369), Constance J. Fournier (14420866), Aaron Rachelle Campbell (14136439), Mary Rose Sallese (10913426), Meghan Allen (10704325)   +4 more
core   +1 more source

Pharmacometric evaluation of pre‐referral rectal artesunate in children with severe malaria

British Journal of Clinical Pharmacology, EarlyView.
Aims Parenteral artesunate is the preferred first‐line treatment for severe malaria. Pre‐referral rectal artesunate suppositories are recommended where parenteral treatment is inaccessible. In this study, we compared dihydroartemisinin exposure and model‐predicted early parasite clearance following rectal artesunate and intravenous artesunate in ...
Ayorinde Adehin, Marie A. Onyamboko, Caterina Fanello, Nicholas J. White, Nicholas P. J. Day, Richard M. Hoglund, Joel Tarning   +6 more
wiley   +1 more source