Results 21 to 30 of about 1,860 (177)

Canonical WNT/β-Catenin Signaling Activated by WNT9b and RSPO2 Cooperation Regulates Facial Morphogenesis in Mice

Frontiers in Cell and Developmental Biology, 2020
The R-spondin (RSPO) family of proteins potentiate canonical WNT/β-catenin signaling and may provide a mechanism to fine-tune the strength of canonical WNT signaling.
Yong-Ri Jin, Xiang Hua Han, Katsuhiko Nishimori, Dan Ben-Avraham, Youn Jeong Oh, Jae-won Shim, Jae-won Shim, Jeong Kyo Yoon, Jeong Kyo Yoon   +8 more
doaj   +1 more source

Governing sustainability in the Thai palm oil-supply chain: the role of private actors

Sustainability: Science, Practice, & Policy, 2022
Private actors are essential partners in the sustainability governance of commodity-supply chains such as palm oil. However, their actual contribution to promoting sustainability is also contested.
Somjai Nupueng, Peter Oosterveer, Arthur P. J. Mol   +2 more
doaj   +1 more source

Evaluating the effectiveness of palm oil certification in delivering multiple sustainability objectives

Environmental Research Letters, 2018
Industrial oil palm plantations in South East Asia have caused significant biodiversity losses and perverse social outcomes. To address concerns over plantation practices and in an attempt to improve sustainability through market mechanisms, civil ...
Courtney L Morgans, Erik Meijaard, Truly Santika, Elizabeth Law, Sugeng Budiharta, Marc Ancrenaz, Kerrie A Wilson   +6 more
doaj   +1 more source

Effect of RSPO3 on inhibiting the growth of colorectal cancer transplanted tumors and increasing NK cell infiltration in vivo

Zhongguo aizheng zazhi, 2023
Background and purpose: The occurrence and development of colorectal cancer involve the activation of multiple oncogenes and the inactivation of tumor suppressor genes.
Cong ZHOU, Lina HE, Xiaojiao CHENG, Tinglei HUANG, Shuiping TU   +4 more
doaj  

Deforestation spillovers from oil palm sustainability certification

Environmental Research Letters, 2020
Environmental policies that impose restrictions within one location may be undermined or reinforced by ‘spillover effects,’ the movement of actors, processes, or knowledge to other locations.
Robert Heilmayr, Kimberly M Carlson, Jason Jon Benedict   +2 more
doaj   +1 more source

Integrating Reinforcement Learning With Explainable Artificial Intelligence for Real‐Time Clinical Decision Support in Dynamic Healthcare Environments

Advanced Intelligent Systems, EarlyView.
A hybrid Reinforcement Learning–Explainable AI framework integrates SHAP and LIME explanations directly into a Deep Q‐Network inference loop for real‐time ICU decision support. Trained on 18 142 mechanically ventilated stays from the eICU database, the system attains 93.0% decision accuracy, 20% fewer errors than RL alone, and a 91% clinician trust ...
Jannatul Ferdaus Disha, MD Faiaz Zaman Dehan, Kazi Md. Tanvir Anzum   +2 more
wiley   +1 more source

Assessing the potential additionality of certification by the Round table on Responsible Soybeans and the Roundtable on Sustainable Palm Oil

Environmental Research Letters, 2016
Multi-stakeholder roundtables offering certification programs are promising voluntary governance mechanisms to address sustainability issues associated with international agricultural supply chains.
Rachael D Garrett, Kimberly M Carlson, Ximena Rueda, Praveen Noojipady   +3 more
doaj   +1 more source

Single-cell time-course transcriptomic analysis reveals epithelial remodeling in human gastric corpus organoids after WNT pathway perturbation [PDF]

Organoid
Background WNT signaling is essential for gastric epithelial stem cell homeostasis. However, the temporal transcriptional dynamics following WNT/RSPO perturbation in human gastric organoids remain unclear.
Na-Yeon Kim, Seung-Pyo Hong, Dakyung Lee, Kyunghyuk Park, Bukyoung Cha, Taekyung Lee, Jong-Il Kim   +6 more
doaj   +1 more source

Zero Deforestation Commitments and Industry 4.0 Enabling Technologies: An Analysis of Their Role in Mitigating Deforestation

Business Strategy and the Environment, EarlyView.
ABSTRACT This study examines the role of corporate zero‐deforestation commitments (ZDCs) and Industry 4.0 (I4.0) enabling technologies in mitigating deforestation. Drawing on data from 110 companies included in the Forest 500 dataset, the research explores whether sustainability commitments and digital innovation influence firms' deforestation ...
Valentina Beretta, Eugenia Parodi, Celine Buschmann   +2 more
wiley   +1 more source

Managing fire risk during drought: the influence of certification and El Niño on fire-driven forest conversion for oil palm in Southeast Asia [PDF]

Earth System Dynamics, 2017
Indonesia and Malaysia have emerged as leading producers of palm oil in the past several decades, expanding production through the conversion of tropical forests to industrial plantations.
P. Noojipady, P. Noojipady, D. C. Morton, W. Schroeder, K. M. Carlson, C. Huang, H. K. Gibbs, D. Burns, N. F. Walker, S. D. Prince   +9 more
doaj   +1 more source