Results 11 to 20 of about 164,355 (372)

Nirsevimab for Prevention of Hospitalizations Due to RSV in Infants.

New England Journal of Medicine, 2023
BACKGROUND The safety of the monoclonal antibody nirsevimab and the effect of nirsevimab on hospitalizations for respiratory syncytial virus (RSV)-associated lower respiratory tract infection when administered in healthy infants are unclear. METHODS In
S. Drysdale, Katrina Cathie, F. Flamein, M. Knuf, Andrea M Collins, Helen C Hill, Friedrich Kaiser, Robert Cohen, Didier Pinquier, C. Felter, N. C. Vassilouthis, Jing Jin, Mathieu Bangert, K. Mari, R. Nteene, Sophie Wague, M. Roberts, P. Tissières, S. Royal, S. Faust   +19 more
semanticscholar   +1 more source

Efficacy and Safety of an mRNA-Based RSV PreF Vaccine in Older Adults.

New England Journal of Medicine, 2023
BACKGROUND Respiratory syncytial virus (RSV) can cause substantial morbidity and mortality among older adults. An mRNA-based RSV vaccine, mRNA-1345, encoding the stabilized RSV prefusion F glycoprotein, is under clinical investigation.
Eleanor Wilson, Jaya Goswami, A. Baqui, P. A. Doreski, Gonzalo Perez-Marc, Khalequ Zaman, Jorge Monroy, Christopher J A Duncan, Mugen Ujiie, Mika Rämet, Lina Pérez-Breva, A. Falsey, Edward E. Walsh, Rakesh Dhar, Lauren Wilson, Jiejun Du, Parinaz Ghaswalla, Archana Kapoor, Lan Lan, Shraddha Mehta, Runa Mithani, C. A. Panozzo, Alana K. Simorellis, B. Kuter, Florian Schödel, Wenmei Huang, Caroline Reuter, Karen Slobod, S. Stoszek, Christine A. Shaw, Jacqueline Miller, R. Das, Grace L Chen   +32 more
semanticscholar   +1 more source

Respiratory infections in children and adolescents in Germany during the COVID-19 pandemic [PDF]

Journal of Health Monitoring, 2023
Background: Before the COVID-19 pandemic, acute respiratory infections (ARIs) in children were mainly characterised by three pathogens: respiratory syncytial viruses (RSV), influenza viruses and rhinoviruses.
Udo Buchholz, Ann-Sophie Lehfeld, Kristin Tolksdorf, Wei Cai, Janine Reiche, Barbara Biere, Ralf Dürrwald, Silke Buda   +7 more
doaj   +1 more source

Adjusting for Case Under-Ascertainment in Estimating RSV Hospitalisation Burden of Older Adults in High-Income Countries: a Systematic Review and Modelling Study

Infectious Disease and Therapy, 2023
Introduction Previous studies suggest diagnostic testing characteristics (i.e. variations in clinical specimens and diagnostic tests) can contribute to underestimation of RSV disease burden.
You Li, D. Kulkarni, Elizabeth Begier, P. Wahi-Singh, B. Wahi-Singh, Bradford J Gessner, H. Nair   +6 more
semanticscholar   +1 more source

Clinico demographic profiling of the Respiratory syncytial virus (RSV) infected children admitted in tertiary care hospital in North India

Journal of Family Medicine and Primary Care, 2021
Background: Acute bronchiolitis is fatal disease involving lower respiratory tract of infants and children of paediatric age group. Respiratory Syncytial Virus (RSV) is responsible for causing more than 70% hospital admissions of children aged less than ...
Charu Singh, Suresh Kumar Angurana, Ishani Bora, Neha Jain, Kanwalpreet Kaur, Subhabrata Sarkar   +5 more
doaj   +1 more source

Efficacy and Safety of an Ad26.RSV.preF-RSV preF Protein Vaccine in Older Adults.

New England Journal of Medicine, 2023
BACKGROUND Respiratory syncytial virus (RSV) can cause serious lower respiratory tract disease in older adults, but no licensed RSV vaccine currently exists.
A. Falsey, Kristi Williams, E. Gymnopoulou, S. Bart, J. Ervin, A. R. Bastian, J. Menten, E. de Paepe, Sjouke Vandenberghe, Eric K. H. Chan, J. Sadoff, M. Douoguih, Benoît Callendret, C. Comeaux, E. Heijnen   +14 more
semanticscholar   +1 more source

Durability of neutralizing RSV antibodies following nirsevimab administration and elicitation of the natural immune response to RSV infection in infants

Nature Medicine, 2023
The prolonged persistence at elevated levels of nirsevimab, an RSV-specific monoclonal antibody, likely accounts for the observed protection from severe disease throughout an RSV season, while it does not prevent the induction of a natural immune ...
Deidre Wilkins, Yuan Yuan, Yue Chang, A. Aksyuk, Beatriz Seoane Núñez, U. Wählby-Hamrén, Tianhui Zhang, M. Abram, Amanda Leach, T. Villafana, M. Esser   +10 more
semanticscholar   +1 more source

Rates of Medically Attended RSV Among US Adults: A Systematic Review and Meta-analysis

Open Forum Infectious Diseases, 2022
Background Adult respiratory syncytial virus (RSV) vaccines are in the late stages of development. A comprehensive synthesis of adult RSV burden is needed to inform public health decision-making. Methods We performed a systematic review and meta-analysis
J. McLaughlin, F. Khan, Elizabeth Begier, D. Swerdlow, L. Jodar, A. Falsey   +5 more
semanticscholar   +1 more source

DYNAMICS OF CHILDHOOD RESPIRATORY INFECTIONS DURING THE COVID-19 PANDEMIC: THE EFFECT OF QUARANTINE АND BEYOND

Central Asian Journal of Medical Hypotheses and Ethics, 2021
Monitoring epidemic processes and the dynamics of the spread of infectious diseases is essential for predicting their distribution and effective planning in healthcare.
Snezhina Lazova, Tsvetelina Velikova
doaj   +1 more source

Effects of COVID-19 Infection Control Strategies on Seasonal Influenza Virus Epidemiology and Evolution [PDF]

Journal of Health Sciences and Surveillance System, 2023
This article has no abstract.
Amir Emami
doaj   +1 more source