Results 11 to 20 of about 127,985 (250)

Global molecular diversity of RSV – the “INFORM RSV” study [PDF]

BMC Infectious Diseases, 2020
Abstract Background Respiratory syncytial virus (RSV) is a global cause of severe respiratory morbidity and mortality in infants. While preventive and therapeutic interventions are being developed, including antivirals, vaccines and monoclonal antibodies, little is known about the global molecular epidemiology of RSV.
Langedijk, Annefleur C., Lebbink, Robert Jan, Naaktgeboren, Christiana, Evers, Anouk, Viveen, Marco C., Greenough, Anne, Heikkinen, Terho, Stein, Renato T., Richmond, Peter, Martinón-Torres, Federico, Nunes, Marta, Hosoya, Mitsuaki, Keller, Christian, Bauck, Monika, Cohen, Robert, Papenburg, Jesse, Pernica, Jeffrey, Hennus, Marije P., Jin, Hong, Tabor, David E., Tovchigrechko, Andrev, Ruzin, Alexey, Abram, Michael E., Wilkins, Deidre, Wildenbeest, Joanne G., Kragten-Tabatabaie, Leyla, Coenjaerts, Frank E J, Esser, Mark T., Bont, Louis J.   +28 more
  +10 more sources

Evaluation of Recombinant Live-Attenuated Respiratory Syncytial Virus (RSV) Vaccines RSV/ΔNS2/Δ1313/I1314L and RSV/276 in RSV-Seronegative Children [PDF]

The Journal of Infectious Diseases, 2022
Abstract Background This United States-based study compared 2 candidate vaccines: RSV/ΔNS2/Δ1313/I1314L, attenuated by NS2 gene-deletion and temperature-sensitivity mutation in the polymerase gene; and RSV/276, attenuated by M2-2 deletion. Methods
Cunningham, Coleen K, Karron, Ruth A, Muresan, Petronella, Kelly, Matthew S, McFarland, Elizabeth J, Perlowski, Charlotte, Libous, Jennifer, Oliva, Jennifer, Jean-Philippe, Patrick, Moye, Jack, Schappell, Elizabeth, Barr, Emily, Rexroad, Vivian, Johnston, Benjamin, Chadwick, Ellen G, Cielo, Mikhaela, Paul, Mary, Deville, Jaime G, Aziz, Mariam, Yang, Lijuan, Luongo, Cindy, Collins, Peter L, Buchholz, Ursula J, Team, the International Maternal Pediatric Adolescent AIDS Clinical Trials 2018 Study   +23 more
openaire   +3 more sources

RSV and non-RSV illness hospitalization in RSV immunoprophylaxis recipients: A systematic literature review

Journal of Clinical Virology, 2020
Respiratory syncytial virus (RSV) immunoprophylaxis (IP) has been shown to reduce RSV hospitalization rates in high-risk infants; however, it is unclear whether RSV IP is associated with increased risk of non-RSV disease, particularly non-RSV hospitalizations.
Adam, Bloomfield, John P, DeVincenzo, Christopher S, Ambrose, Leonard R, Krilov   +3 more
openaire   +2 more sources

Multicenter clinical evaluation of the Luminex Aries Flu A/B & RSV assay for pediatric and adult respiratory tract specimens [PDF]

, 2017
Influenza A and B viruses and respiratory syncytial virus (RSV) are three common viruses implicated in seasonal respiratory tract infections and are a major cause of morbidity and mortality in adults and children worldwide. In recent years, an increasing
Buller, Richard S, Dunbar, Sherry, Juretschko, Stefan, Mahony, James, Manji, Ryhana, Rao, Arundhati, Walker, Kimberly   +6 more
core   +2 more sources

SARS-CoV-2 Vaccines: A Brief Review

Pediatric Respirology and Critical Care Medicine, 2020
SARS-CoV-2 has immensely changed the landscape in how vaccines are researched and developed. The timeline truncated for the propose of meeting the grave demand. Children stand to benefit from herd immunity for multiple reasons. Protection from SARS-CoV-2
Brandon Chatani, Daniel K. Ng
doaj   +1 more source

Molecular Detection of Upper Respiratory Tract Viral Infection with RSV, HPIV & Adenovirus among SARS-CoV2 Negative patients with respiratory illness admitted in tertiary care hospital in Eastern India

Archives of Pharmaceutical Sciences Ain Shams University, 2023
Background: The most prevalent disease-causing agents in humans are respiratory viruses, which have a global influence on morbidity and death. The Adenovirus, respiratory syncytial virus (RSV), and parainfluenza viruses (HPIV) are the dominant ...
Nivedita Mukherjee , Swati Nayek, Sanjoy Mondal, Tanusri Biswas, Arghya Nath   +4 more
doaj   +1 more source

RSV awareness, risk perception, causes, and terms: Perspectives of pregnant and lactating women in Kenya to inform demand generation efforts for maternal RSV vaccines

Human Vaccines & Immunotherapeutics, 2023
Respiratory syncytial virus (RSV) causes a substantial proportion of acute lower respiratory tract infections (LRTI) among infants. In low- and middle-income countries, RSV may be responsible for approximately 40% of all hospital admissions of infants ...
Rupali J. Limaye, Berhaun Fesshaye, Prachi Singh, Ruth A. Karron   +3 more
doaj   +1 more source

Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state [PDF]

, 2017
Human respiratory syncytial virus (RSV) is the main cause of lower respiratory tract infections in young children. The RSV fusion protein (F) is highly conserved and is the only viral membrane protein that is essential for infection.
Chen, Man, Gilman, Morgan SA, Graham, Barney S, Kabeche, Stephanie C, Kanekiyo, Masaru, Mas, Vicente, McLellan, Jason S, Melero, José A, Rossey, Iebe, Saelens, Xavier, Schepens, Bert, Sedeyn, Koen, Spitaels, Jan, Wrapp, Daniel   +13 more
core   +2 more sources

Oral administration of Clostridium butyricum rescues streptomycin-exacerbated respiratory syncytial virus-induced lung inflammation in mice

Virulence, 2021
Changes in the intestinal microbiota indirectly impact the health of mucosa distal to the intestine, particularly the respiratory tract. However, the effects of intestinal microbiota dysbiosis on the regulation of respiratory syncytial virus (RSV ...
Wenwen Zhu, Jia Wang, Na Zhao, Rui Zheng, Dalu Wang, Weiwei Liu, Beixing Liu   +6 more
doaj   +1 more source

Kinetics of the neutralizing antibody response to respiratory syncytial virus infections in a birth cohort [PDF]

, 2013
The kinetics of respiratory syncytial virus (RSV) neutralizing antibodies following birth, primary and secondary infections are poorly defined. The aims of the study were to measure and compare neutralizing antibody responses at different time points in ...
Cane, Patricia, Medley, Graham, Mutunga, M. N., Nokes, D. James, Okiro, Emelda A., Sande, Charles J.   +5 more
core   +1 more source