Results 21 to 30 of about 32,704 (143)
Journal of Clinical Virology, 2020 Respiratory syncytial virus (RSV) immunoprophylaxis (IP) has been shown to reduce RSV hospitalization rates in high-risk infants; however, it is unclear whether RSV IP is associated with increased risk of non-RSV disease, particularly non-RSV hospitalizations.
Leonard R. Krilov +3 more
openaire +3 more sources
Single-Dose Nirsevimab for Prevention of RSV in Preterm Infants.
New England Journal of Medicine, 2020 BACKGROUND Respiratory syncytial virus (RSV) is the most common cause of lower respiratory tract infection in infants, and a need exists for prevention of RSV in healthy infants.
M. P. Griffin +11 more
semanticscholar +1 more source
BMC Infectious Diseases, 2021 Background Respiratory syncytial virus (RSV) is the main cause of infant and child hospitalizations. The study objective is to estimate the RSV-associated hospitalizations and economic burden in young children in France to inform future preventive ...
C. Demont +8 more
semanticscholar +1 more source
Health Science Reports, 2018 A study of infant bronchiolitis–coded episodes described the proportion of events attributable to respiratory syncytial virus (RSV) and demonstrated that episodes occurring during the peak months of winter viral season, among younger infants, and among those with higher levels of care, were more likely to be attributable to RSV.
openaire +3 more sources
RSV Replication, Transmission, and Disease Are Influenced by the RSV G Protein
Viruses, 2022 It is important to understand the features affecting virus replication, fitness, and transmissibility as they contribute to the outcome of infection and affect disease intervention approaches. Respiratory syncytial virus (RSV) is a major contributor to respiratory disease, particularly in the infant and elderly populations.
Harrison C. Bergeron, Ralph A. Tripp
openaire +3 more sources
medRxiv, 2021 Wastewater based epidemiology (WBE) uses concentrations of infectious agent targets in wastewater to infer infection trends in the contributing community.
B. Hughes +6 more
semanticscholar +1 more source
Immunity to RSV in Early-Life [PDF]
Frontiers in Immunology, 2014 Respiratory Syncytial Virus (RSV) is the commonest cause of severe respiratory infection in infants, leading to over 3 million hospitalizations and around 66,000 deaths worldwide each year. RSV bronchiolitis predominantly strikes apparently healthy infants, with age as the principal risk factor for severe disease. The differences in the immune response
Lambert, L +3 more
openaire +6 more sources
The Global Epidemiology of RSV in Community and Hospitalized Care: Findings From 15 Countries
Open Forum Infectious Diseases, 2021 Background Respiratory syncytial virus (RSV) is one of the leading causes of acute respiratory tract infections. To optimize control strategies, a better understanding of the global epidemiology of RSV is critical.
Lisa Staadegaard +33 more
semanticscholar +1 more source
De novo protein design enables the precise induction of RSV-neutralizing antibodies
Science, 2020 TopoBuilding precision vaccines To induce strong and targeted neutralizing antibody (nAb) responses against vaccine targets, one strategy has been to use computationally designed immunogens. However, the structural complexity of many known neutralization
F. Sesterhenn +31 more
semanticscholar +1 more source
Vaccines, 2023 RSV is divided into two antigenic subtypes, RSV A and RSV B, which is largely based on the variation in the G protein, while the fusion protein F is more conserved and a target for antibody-mediated neutralization. Here we evaluate the breadth of the protective immune responses across RSV A and RSV B subtypes, induced by vaccines based on the RSV A ...
Freek Cox +12 more
openaire +3 more sources