Results 1 to 10 of about 13,405 (223)

Cross species extrapolation of the disruption of thyroid hormone synthesis by oxyfluorfen using in vitro data, physiologically based pharmacokinetic (PBPK), and thyroid hormone kinetics models

open access: yesCurrent Research in Toxicology, 2023
The thyroid hormones play key roles in physiological processes such as regulation of the metabolic and cardiac systems as well as the development of the brain and surrounding sympathetic nervous system.
Rhylee Decrane   +4 more
doaj   +1 more source

Application of an Accessible Interface for Pharmacokinetic Modeling and In Vitro to In Vivo Extrapolation

open access: yesFrontiers in Pharmacology, 2022
Regulatory toxicology testing has traditionally relied on in vivo methods to inform decision-making. However, scientific, practical, and ethical considerations have led to an increased interest in the use of in vitro and in silico methods to fill data ...
David E. Hines   +5 more
doaj   +1 more source

RTP

open access: yesProceedings of the 2013 ACM SIGMOD International Conference on Management of Data, 2013
In the cloud services industry, a key issue for cloud operators is to minimize operational costs. In this paper, we consider algorithms that elastically contract and expand a cluster of in-memory databases depending on tenants' behavior over time while maintaining response time guarantees.We evaluate our tenant placement algorithms using traces ...
Jan Schaffner   +6 more
openaire   +3 more sources

Assessment of safety and tolerability of remogliflozin etabonate (GSK189075) when administered with total daily dose of 2000 mg of metformin

open access: yesBMC Pharmacology and Toxicology, 2021
Background Patients with type 2 diabetes mellitus (T2DM) are characterized by an elevated glycemic index and are at a higher risk for complications such as cardiovascular disease, nephropathy, retinopathy and peripheral neuropathy.
Robert Dobbins   +8 more
doaj   +1 more source

Incidence and survival of skin melanoma in Puglia: A comparison with the rest of Italy [PDF]

open access: yesJournal of Health and Social Sciences, 2016
Introduction: There is a wide heterogeneity in incidence, prevalence, mortality and survival of skin melanoma through the world and in Italy as well. In this study we investigated, for the first time, incidence, mortality and survival of skin melanoma in
Anna Maria Nannavecchia   +9 more
doaj   +1 more source

Organo-Silica Membrane Prepared from TEOS-TEVS Modified with Organic-Acid Catalyst for Brackish Water Desalination

open access: yesJurnal Rekayasa Kimia & Lingkungan, 2021
The sol gel process is one of the processes used in the manufacture of thin films on membranes because it can control the pore size in the resulting silica matrix.
Muthia Elma   +9 more
doaj   +1 more source

Room Temperature Phosphorescent (RTP) Thermoplastic Elastomers with Dual and Variable RTP Emission, Photo‐Patterning Memory Effect, and Dynamic Deformation RTP Response

open access: yesAdvanced Science, 2022
Room temperature phosphorescent (RTP) polymers have advantages of strength, toughness, and processing and application flexibility over organic small molecular crystals, but the current RTP polymers are all from rigid plastics and involve chemical linkage
Yuefa Zhang   +7 more
doaj   +1 more source

Lisboa, 1975. A correspondência da Embaixada alemã sobre o refúgio concedido a quatro oficiais golpistas

open access: yesEstudos do Século XX, 2021
Os oficiais golpistas derrotados em 11 de março de 1975 foram em parte afastados dos seus cargos, em parte detidos ou, em menor número, refugiaram-se na vizinha Espanha.
António Louçã
doaj   +1 more source

Formation Process and Properties of Ohmic Contacts Containing Molybdenum to AlGaN/GaN Heterostructures

open access: yesAdvances in Electrical and Electronic Engineering, 2016
Properties of wide bandgap semiconductors as chemical inertness to harsh conditions and possibility of working at high temperature ensure possible applications in the field as military, aerospace, automotive, engine monitoring, flame detection and solar ...
Wojciech Macherzynski   +4 more
doaj   +1 more source

A Study for Expanding Application Sites for Rotigotine Transdermal Patch

open access: yesParkinson's Disease, 2020
The rotigotine transdermal patch (RTP) is a dopamine agonist used to treat Parkinson’s disease (PD). Some PD patients cannot continue RTP treatment due to application site reactions.
Hitoshi Kujirai   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy