Results 81 to 90 of about 28,414 (236)

Exception from Informed Consent and Waiver of Informed Consent for Comparative Effectiveness Trials in Emergency Care Research

Ethics &Human Research, Volume 48, Issue 1, Page 31-41, January–February 2026.
ABSTRACT For many of the decisions made in the clinical care setting, clinicians lack evidence to inform which treatment would result in the best patient outcomes. This problem is particularly common in emergency care, a field in which the condition of the patient and the urgent nature of the treatment often preclude research conducted using ...
Jonathan D. Casey, Matthew W. Semler, Jeremy Brown, Clifton W. Callaway, Stephanie C. DeMasi, Neal W. Dickert, Luke Gelinas, Francis X. Guyette, Ann R. Johnson, Wesley H. Self, Todd W. Rice, Stephanie R. Morain   +11 more
wiley   +1 more source

Identifying factors relevant in the assessment of return-to-work efforts in employees on long-term sickness absence due to chronic low back pain: a focus group study

BMC Public Health, 2012
Background Efforts undertaken during the return to work (RTW) process need to be sufficient to prevent unnecessary applications for disability benefits.
Muijzer Anna, Geertzen Jan H, de Boer Wout E, Groothoff Johan W, Brouwer Sandra   +4 more
doaj   +1 more source

Longitudinal Outcome Evaluations of Interdisciplinary Multimodal Pain Treatment Programs for Patients With Chronic Primary Musculoskeletal Pain: A Living Systematic Review

European Journal of Pain, Volume 30, Issue 1, January 2026.
ABSTRACT Background and Objectives Interdisciplinary Multimodal Pain Treatment (IMPT), grounded in the biopsychosocial model, is strongly recommended for patients with chronic primary pain. A base review found that IMPT participation leads to sustained improvements in wellbeing, but substantial heterogeneity in program dose and content limited ...
Elise Cnockaert, Kirsty Musch, Stefan Elbers, Albère Köke, Jessica Van Oosterwijck, Ivan Huijnen, Rob Smeets   +6 more
wiley   +1 more source

Therapeutic Effects of Nizubaglustat in a Mouse Model of GM2 Gangliosidosis

Journal of Inherited Metabolic Disease, Volume 49, Issue 1, January 2026.
ABSTRACT Nizubaglustat is a novel selective inhibitor of glucosylceramide synthase (GCS) and the non‐lysosomal glucocerebrosidase (NLGase, GbA2) with brain penetrant properties. It is currently in clinical development as an oral treatment for rare lysosomal storage diseases with neurological involvement. One such disease group called GM2 gangliosidosis,
Kyle Landskroner, Kshitiz Singh, Melissa Mitchell, Jagdeep S. Walia   +3 more
wiley   +1 more source

Association of socioeconomic status on return to work following primary total hip arthroplasty: a Danish population-based cohort study on 9,431 patients from 2008–2018

Acta Orthopaedica
Background and purpose: Return to work (RTW) following primary total hip arthroplasty (THA) is important for patients and society. We aimed to investigate the association between markers of socioeconomic status (SES) and RTW after primary THA, and ...
Peter Alsing, Julie B Pajaniaye, Martin G Stisen, Søren Overgaard, Erzsébet Horváth-Puhó, Inger Mechlenburg, Alma B Pedersen   +6 more
doaj   +1 more source

Return to Work after a Stroke in Working Age Persons; A Six-Year Follow Up. [PDF]

PLoS ONE, 2017
Stroke is one of the most common and resource intensive diseases for society. Stroke in the working age population is increasing in different parts of the world.
Emma Westerlind, Hanna C Persson, Katharina S Sunnerhagen   +2 more
doaj   +1 more source

On the social induction of Alzheimer's disease: An index theorem aging model for amyloid formation [PDF]

, 2011
The central 'risk factor' for Alzheimer's disease (AD) is age. From first principles, we construct a mathematical model of protein folding and its in vivo regulation that gives this result in a natural manner.
Deborah Wallace, Rodrick Wallace
core   +1 more source

Instantaneous noise-based logic

, 2010
We show two universal, Boolean, deterministic logic schemes based on binary noise timefunctions that can be realized without time-averaging units. The first scheme is based on a new bipolar random telegraph wave scheme and the second one makes use of the
Khatri, Sunil, Kish, Laszlo B., Peper, Ferdinand   +2 more
core   +1 more source

A Redox‐Active Tetrathiafulvalene‐Based 3D Covalent Organic Framework with scu Topology for Controllable Charge Transport

Small Science, Volume 6, Issue 1, January 2026.
This article presents the designed construction of a high‐connectivity, electrochemically tunable 3D covalent organic framework (TU‐48) with a scu‐c topology, incorporating tetrathiafulvalene‐based building blocks to enable multidimensional charge transport and achieve enhanced electrical conductivity through redox modulation and iodine doping.
Tsukasa Irie, Jonas F. Pöhls, Saikat Das, Jin Sakai, Kohki Sasaki, Mika Nozaki, Yu Zhao, Luming Yang, Marina Bennati, Sourav Ghosh, Ranjit Thapa, Roland A. Fischer, R. Thomas Weitz, Qianrong Fang, Yuichi Negishi   +14 more
wiley   +1 more source

Barriers and facilitators of return to work for loss of income claimants: Healthcare workers’ perspectives

African Journal of Disability
Background: Road traffic accidents (RTAs) are a global and public health concern affecting a third of the world’s population mainly in low- to middle-income countries, particularly affecting young people.
Gofaone L. Modise, Catharina J.E. Uys, Eileen du Plooy   +2 more
doaj   +1 more source