Consideration of Easygard Post Design on the Base of Advances Concurrent Engineering Tool [PDF]
The essence of CE is the integration of product design and process planning into one common activity. Concurrent design helps improve the quality of early design decisions and has a tremendous impact on life-cycle cost of the product.
Alexander Sharmazanashvili +1 more
core +1 more source
Multimodal Cross‐Attentive Graph‐Based Framework for Predicting In Vivo Endocrine Disruptors
A multimodal cross‐attentive graph neural network integrates molecular graphs with androgen and estrogen adverse outcome pathway (AOP)–anchored in vitro assay signals to predict in vivo endocrine disruption. By fusing information on Tier‐1 AOP logits with chemical structures, the framework achieves high accuracy and provides assay‐traceable ...
Eder Soares de Almeida Santos +6 more
wiley +1 more source
DYNAMIC ANALYSIS OF HDRB ISOLATED BRIDGES BASED ON SIMPLIFIED MECHANICAL MODEL
High damping rubber bearing( HDRB) as a kind of isolation bearing has the functions like bearing capacity,restoring force and damping( energy absorption).
ZHANG JuHui, CHEN Yang, YAO ZhaoWei
doaj
A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang +15 more
wiley +1 more source
Analysis of an all-metallic resilient-pad gas-lubricated thrust bearing [PDF]
A resilient-pad gas thrust bearing that does not contain any elastomers in the bearing assembly is described and analyzed. The bearing consists of sector-shaped pads mounted asymmetrically on resilient foil beams. The effects of bearing design parameters
Anderson, W. J.
core +1 more source
Novel Vascular‐Adaptive Liquid Metal Microspheres Enable Visualized Arterial Embolization Therapy
We present drug‐loaded liquid metal microspheres (X‐MEN) as a novel agent for image‐guided arterial embolization. With inherent radiopacity and superior deformability, X‐MEN enables real‐time monitoring and conforms tightly to irregular vessels. This approach ensures precise, long‐lasting embolization without recanalization, addressing critical ...
Chenyu Shen +14 more
wiley +1 more source
Status of Designs of Lunar Surface Vehicles [PDF]
This report summarizes the activities of the various organizations that have been giving some thought and design effort to producing a lunar surface traversing vehicle. It is a state-of-the-art rather than a technical report.
Bliss, P. H.
core +1 more source
Physics‐Embedded Neural Network: A Novel Approach to Design Polymeric Materials
Traditional black‐box models for polymer mechanics rely solely on data and lack physical interpretability. This work presents a physics‐embedded neural network (PENN) that integrates constitutive equations into machine learning. The approach ensures reliable stress predictions, provides interpretable parameters, and enables performance‐driven, inverse ...
Siqi Zhan +8 more
wiley +1 more source
Bioinspired Adaptive Leg‐Claw Enables Robust Perching and Grasping for UAVs
Inspired by owl limb morphology and bat roosting behavior, this study presents a bioinspired adaptive leg‐claw mechanism that enables UAVs to perform robust and versatile perching and grasping. The design integrates a four‐link tibial structure, tension‐driven deformable feet, and active control, enabling stable perching on various branches and ...
Tianyu Cheng +6 more
wiley +1 more source
The Faraday Scalpel: Electrochemical Nerve Lesioning Mechanisms Studied in Invertebrate Models
Direct‐current produces nerve lesioning through discrete electrochemical reactions. Using hypoxia‐sensitive locust nerves and hypoxia‐tolerant leech nerves, we map three injury pathways: cathodic oxygen reduction, cathodic alkalization, and anodic chloride oxidation. These findings establish electrochemical lesioning—the “Faraday Scalpel”—as a precise,
Petra Ondráčková +5 more
wiley +1 more source

