Results 91 to 100 of about 2,622 (248)

Cost‐utility analysis of nusinersen–risdiplam switch in patients with spinal muscular atrophy in Croatia: A discrete event simulation model

British Journal of Clinical Pharmacology, EarlyView.
Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić, Ivana Stević, Elvira Meni Maria Gkrinia, Dinko Vitezić, Slobodan Janković   +4 more
wiley   +1 more source

Marine silicon for biomedical sustainability

BMEMat, EarlyView.
Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han, Zhibo Yang, Wei Xia, Chengtie Wu   +3 more
wiley   +1 more source

Reading hominin life history in fossil bones and teeth: methods to test hypotheses regarding its evolution

Biological Reviews, EarlyView.
ABSTRACT Human life history is derived compared to that of our closest living relatives, the great apes. It has been suggested that these derived traits are causally related to aspects of our ecology, social behaviour and cognitive abilities. However, resolving this requires that we know the evolutionary trajectory of our distinctive pattern of growth,
Paola Cerrito, Judith M. Burkart, Carel van Schaik   +2 more
wiley   +1 more source

An Unexpected Near Term Pregnancy in a Rudimentary Uterine Horn

Case Reports in Obstetrics and Gynecology, 2013
Unicornuate uterus occurs due to a complete or partial nondevelopment of one Mullerian duct; sometimes it is associated with a rudimentary horn, which can communicate or not with uterine cavity or contain functional endometrium.
Elisabete Gonçalves, João Pedro Prata, Sandra Ferreira, Rita Abreu, Jorge Mesquita, Agostinho Carvalho, Paula Pinheiro   +6 more
doaj   +1 more source

National Environmental Policies and Corporate Green Innovation: The Mirroring Versus Substitution Hypotheses

Business Strategy and the Environment, EarlyView.
ABSTRACT Drawing on comparative institutional theory, we study the nature and magnitude of the effects of national environmental policies on corporate green innovation in developed versus emerging markets. Using a sample of 1831 listed firms in 34 countries from 2002 to 2020, we find that national environmental policies increase corporate green ...
Ivan Miroshnychenko, Knut Haanaes, Julia Binder   +2 more
wiley   +1 more source

Medical Management of Problematic Sexual Arousal for People With a Sexual Conviction in England and Wales: Challenges, Learning and Progress

Criminal Behaviour and Mental Health, EarlyView.
ABSTRACT Background In England and Wales, the primary treatments for individuals convicted of sexual offences are psychological. However, medication to manage problematic sexual arousal (MMPSA) is gaining importance as an alternative. This article reviews the current evidence surrounding the MMPSA approach.
Belinda Winder, D. Grubin, M. Underwood, Z. Antoniadis, M. Carvalheiro, E. Marshall, C. Norman, R. Bourne, A. Kaul   +8 more
wiley   +1 more source

Form and load transfer aspects of foundation systems: Case‐based implementation and adaptation for buildings

Deep Underground Science and Engineering, EarlyView.
Upon conceptualization of structural behavior, foundations in terms of their form are divided into linear (1D), planar (2D), and volumetric (3D). Regarding the load transfer mechanisms, linear foundation systems are considered vector‐acting, planar foundations are divided into section and surface‐acting, and volumetric ones are recognized as block ...
Abolfazl Eslami, Amirhossein Ebrahimipour, Meysam Imani, Reza Imam, Pinqiang Mo   +4 more
wiley   +1 more source

Embryonic cerebrospinal fluid pressure in fetal mice in utero: External factors pressurize the intraventricular space

Developmental Dynamics, EarlyView.
Abstract Background Previous experiments inducing leakage of embryonic cerebrospinal fluid (CSF) suggest the necessity of intraventricular CSF pressure (PCSF) for brain morphogenesis. Nevertheless, how embryonic PCSF occurs is unclear, especially in utero. Results Using a Landis water manometer, we measured PCSF in fetal mice isolated from the amniotic
Koichiro Tsujikawa, Reina Muramatsu, Takaki Miyata   +2 more
wiley   +1 more source

Neural Network–Assisted Metasurface Retroreflector With Wide‐Angle Adaptivity

Electron, EarlyView.
This work proposes a wide‐angle, multi‐polarization, self‐sensing, and self‐adaptive intelligent metasurface retroreflector, with a planar profile and ultrathin thickness. By integrating a pre‐trained artificial neural network (ANN), the metasurface retroreflector can recognize the incident angle and promptly adapt to changes in the incoming wave.
Jing Ning, Xunfan Wang, Kun Duan, Weixu Yang, Junming Zhao, Tian Jiang, Ke Chen, Yijun Feng   +7 more
wiley   +1 more source

Epilepsy surgery: From bench to the clinics

Epilepsia Open, EarlyView.
Abstract Objective Recent advances in epilepsy surgery in patients with intractable epilepsy make it possible to study the mechanism of epilepsy in human brains. However, the true extent and propagation of each epileptogenic area from the epileptogenic focus in each patient is still difficult to perform “epilepsy cure” by surgery.
Tatsuya Tanaka
wiley   +1 more source