Results 51 to 60 of about 2,622 (248)
Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology
Advanced Science, EarlyView.Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto +11 more
wiley +1 more source
Angewandte Chemie, EarlyView.Electrochemical measurements as single aqueous microdroplets collide with electrode interfaces reveal nanoscale wetting dynamics. By tuning electrostatic repulsion, we control contact formation and probe surface interactions well beyond the optical diffraction limit.
Kathryn J. Vannoy +2 more
wiley +2 more sources
A near miss case of ruptured non-communicating rudimentary horn pregnancy in primigravida
Middle East Fertility Society Journal, 2017 Rudimentary horn pregnancy is a rare site of ectopic pregnancy. Diagnosis of rudimentary horn pregnancy requires a high index of suspicion as it can be easily missed during routine ultrasound scan.
Ahmed M. Abbas +4 more
doaj +1 more source
Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits
Advanced Science, EarlyView.A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao +8 more
wiley +1 more source
Substituent‐Based Modulation of Self‐Assembly and Immunogenicity of Amphipathic Peptides
Advanced Science, EarlyView.This study systematically investigates how positional and subtle changes, such as substituents on the phenyl ring attached to short amphipathic peptides, influence their self‐assembly, fibril morphology, and immunogenic responses. ABSTRACT Self‐assembled peptide‐based biomaterials provide versatile platforms for biomedical uses, featuring customizable ...
Anirban Das +13 more
wiley +1 more source
Angewandte Chemie, EarlyView.A large variety of chemistry‐based ubiquitin probes have been developed. ABSTRACT Ubiquitin (Ub) and ubiquitin‐like proteins (Ubls) orchestrate diverse cellular processes through reversible post‐translational modification of target proteins. Their conjugation is governed by a cascade of E1 activating, E2 conjugating, and E3 ligating enzymes, while ...
Saibal Chanda, Wenshe Ray Liu
wiley +2 more sources
A 22-Week Ruptured Rudimentary Uterine Horn Pregnancy
Gynecology Obstetrics & Reproductive Medicine, 2010 Rudimentary horn pregnancy is a rare but serious obstetric event. We presented a case of rudimentary horn pregnancy ruptured at 22 weeks. Rudimentary horn excision was performed during exploration.
Ayşe Nur Evrenos +3 more
doaj
Advanced Science, EarlyView.This study introduces a novel metamaterial absorber integrating water as a lossy medium with patterned indium tin oxide (ITO) films to achieve simultaneous optical transparency and ultra‐wideband electromagnetic absorption over 0.52‐40 GHz. It effectively overcomes the limitations of conventional opaque and bulky shielding materials, offering a ...
Xiaojun Huang +5 more
wiley +1 more source
Advanced Science, EarlyView.Photonic time crystals (PTCs) are systems in which electromagnetic parameters are modulated periodically in time, producing momentum bandgaps via temporal scattering rather than spatial Bragg processes. This review examines the theoretical frameworks, modeling, and computational tools for time‐varying media, and summarizes experimental demonstrations ...
Ranjan Kumar Patel +3 more
wiley +1 more source
Recurrence of Uterine Rupture in a Pseudo-Unicornuate Uterus at 17 Weeks of Amenorrhea: Case Report and Literature Review [PDF]
Libyan Journal of Medicine, 2009 Pregnancy in a rudimentary horn is a very rare condition. It is responsible for several complications.Prognosis is reserved because the natural evolution generally leads to a cataclysmic uterine ruptureat the beginning of the second trimester ...
Banani A +6 more
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